Results 141 to 150 of about 804,907 (316)
, 2008 Objectives: To phenotypically and genotypically characterize 11 strains (isolated in four different centres) exhibiting penicillin MIC of 8-32 mg/L among isolates of the SPICE project. Nine isolates were from Romania (9/162; 5.56%) and two from Poland (2/
Gracia, Matilde +11 more
core +1 more source
The Soviet Military Microbiologists’ Contribution to the Victory in the Great Patriotic War
Вестник войск РХБ защитыHighlights Branch of the 48 Central Research Institute (Kirov) of the Ministry of Defence of the Russian Federation was one of the leading research institutions in the Soviet Union that dealt with dangerous and hazardоus contagious diseases and tried to ...
A. S. Tumanov +6 more
doaj +1 more source
Aging and Cancer, EarlyView.Natural products target the aging kidney in diabetic nephropathy by restoring the AMPK–SIRT1–Nrf2 axis, reducing oxidative stress, inflammation, fibrosis, and cellular senescence while enhancing mitochondrial biogenesis and antioxidant defenses.
Sherif Hamidu +8 more
wiley +1 more source
High-content aminoglycoside disks for determining aminoglycoside-penicillin synergy against Enterococcus faecalis [PDF]
, 1988 We investigated the use of high-content aminoglycoside disks for determining Enterococcus faecalis susceptibility to aminoglycoside-penicillin synergy.
Torres, C. [0000-0003-3709-1690] +1 more
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Epilepsy‐Associated Variants of a Single SCN1A Codon Exhibit Divergent Functional Properties
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Pathogenic variants in SCN1A, which encodes the voltage‐gated sodium channel NaV1.1, are associated with multiple epilepsy syndromes exhibiting a range of clinical severity. SCN1A variants are reported in different syndromes, including Dravet syndrome, which is associated with loss‐of‐function, whereas neonatal/infantile‐onset ...
Lanie N. Liebovitz +3 more
wiley +1 more source
The enzymology of Streptococcus pneumoniae peptidoglycan polymerisation [PDF]
Bacterial cell survival depends on intact peptidoglycan, an extensive cell wall polymer of alternating N-acetylglucosamine and N-acetylmuramic acid residues, cross-linked by short peptides.
Abrahams, Katherine A.
core
Antimicrobial‐associated encephalopathy due to ampicillin
Clinical Case ReportsKey Clinical Message Because the β‐lactam ring has a molecular structure similar to that of gamma‐aminobutyric acid (GABA) neurotransmitters, it binds to GABA A receptors and inhibits GABAergic transmission, causing AAE.
Naoya Mizutani, Tsuneaki Kenzaka
doaj +1 more source
The Critical Role of Penicillin in Syphilis Treatment and Emerging Resistance Challenges
DiseasesSyphilis, a global healthcare burden, is a sexually transmitted infection caused by the spirochete Treponema pallidum, a spiral-shaped, Gram-negative obligate human pathogen.
Arun Kumar Jaiswal +4 more
doaj +1 more source
ALDOA Promotes Glycolysis and NLRP3/GSDMD Pyroptosis to Accelerate ALS Progression
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Amyotrophic lateral sclerosis (ALS) is characterized by progressive motor neuron degeneration. Glycolytic dysregulation is implicated in disease progression, yet the underlying mechanisms remain unclear. This study investigates how Aldolase A (ALDOA) drives ALS progression through glycolysis‐mediated motor neuron pyroptosis.
Kaixin Yan +9 more
wiley +1 more source