Results 51 to 60 of about 637,867 (346)

Emergence of Meropenem Resistance Among Cefotaxime Non-susceptible Streptococcus pneumoniae: Evidence and Challenges

open access: yesFrontiers in Microbiology, 2022
The principal causative agent of acute bacterial meningitis (ABM) in children and the elderly is Streptococcus pneumoniae, with a widespread increase in penicillin resistance.
Rosemol Varghese   +9 more
doaj   +1 more source

Surfactant-free purification of membrane protein complexes from bacteria: application to the staphylococcal penicillin-binding protein complex PBP2/PBP2a [PDF]

open access: yes, 2014
Surfactant-mediated removal of proteins from biomembranes invariably results in partial or complete loss of function and disassembly of multi-protein complexes. We determined the capacity of styrene-co-maleic acid (SMA) co-polymer to remove components of
Dafforn, Timothy R   +8 more
core   +3 more sources

Penicillin-binding proteins in Borrelia burgdorferi [PDF]

open access: yesJournal of Bacteriology, 1990
Penicillin-binding proteins were identified in Borrelia burgdorferi membranes. A 94-kilodalton penicillin-binding protein was the first to be labeled with tritiated penicillin and was the first band to disappear in a competition experiment. Its binding ability was destroyed when membranes were preboiled. In addition, several of these penicillin-binding
C, Urban   +4 more
openaire   +2 more sources

Designing a novel multi-epitope vaccine to evoke a robust immune response against pathogenic multidrug-resistant Enterococcus faecium bacterium

open access: yesGut Pathogens, 2022
Enterococcus faecium is an emerging ESKAPE bacterium that is capable of causing severe public health complications in humans. There are currently no licensed treatments or vaccinations to combat the deadly pathogen.
Jyotirmayee Dey   +8 more
doaj   +1 more source

Clinical characteristics, specific resistance patterns, and molecular mechanisms of carbapenem-resistant Morganella morganii isolates

open access: yesFrontiers in Cellular and Infection Microbiology
ObjectivesThe emergence and spread of carbapenem-resistant Morganella morganii (M. morganii) pose a serious global challenge. This study aimed to investigate the clinical characteristics, resistance patterns, and molecular mechanisms of carbapenem ...
Xiangkuo Zheng   +8 more
doaj   +1 more source

Studies on Resistance to Vegetative (Vip3A) and Crystal (Cry1A) Insecticidal Toxins of Bacillus thuringiensis in Heliothis virescens (Fabricius) [PDF]

open access: yes, 2009
Bacillus thuringiensis (Bt) toxins expressed in commercial transgenic crop varieties are all δ-endotoxins (Cry toxins) but the identification of novel vegetative insecticidal proteins (Vip toxins) has extended the range of insecticidal proteins derived
Pickett, Brian R, Pickett, Brian R
core   +1 more source

Escherichia coli EHEC Germany outbreak preliminary functional annotation using BG7 system [PDF]

open access: yes, 2011
We have annotated the European outbreak E. coli EHEC genome sequenced by BGI (6-2-2011) and assembled with MIRA by Nick Loman (6-2-2011 ). Our system BG7, Bacterial Genome annotation of Era7 Bioinformatics, predicts ORFs and annotates them based on ...
Eduardo Pareja   +4 more
core   +2 more sources

Penicillin-binding proteins of Haemophilus ducreyi [PDF]

open access: yesAntimicrobial Agents and Chemotherapy, 1989
The penicillin-binding protein (PBP) profile of Haemophilus ducreyi was determined by a whole-cell-labeling assay. Only two major PBPs, of molecular weights 90,000 (PBP 1) and 38,500 (PBP 2), were detected in six of eight strains studied. Competition binding experiments and the attendant morphological effects suggested that PBP 1 was either a ...
B C, Lee, L E, Bryan
openaire   +2 more sources

Integrative structural biology of the penicillin-binding protein-1 from Staphylococcus aureus, an essential component of the divisome machinery

open access: yesComputational and Structural Biotechnology Journal, 2021
The penicillin-binding proteins are the enzyme catalysts of the critical transpeptidation crosslinking polymerization reaction of bacterial peptidoglycan synthesis and the molecular targets of the penicillin antibiotics.
Siseth Martínez-Caballero   +12 more
doaj   +1 more source

Penicillin-binding proteins in Proteus species [PDF]

open access: yesJournal of Bacteriology, 1979
Penicillin-binding proteins in three species of Proteus, Proteus mirabilis, P. morganii, and P. rettgeri, were investigated by sodium dodecyl sulfate-polyacrylamide slab gel electrophoresis. Penicillin-binding proteins in these Proteus species were compared with those in Escherichia coli K-12.
S, Ohya   +3 more
openaire   +2 more sources

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