Results 261 to 270 of about 561,009 (296)

Penicillin-binding proteins of clostridia

Current Microbiology, 1993
The penicillin-binding protein (PBP) profiles of 33Clostridium perfringens and sixClostridium species isolated from clinically significant infections were analyzed. Three new PBPs—PBPs 2B, 4B, and 5B (84, 70, and 49 kDa respectively)—and a high-molecular-weight PBP 6 (45 kDa) were demonstrated in theC. perfringens isolates. In addition to PBPs 1 and 2,
Lynda Chalkley, Ingrid Van der Westhuyzen   +1 more
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Penicillin-binding proteins ofRhodospirillum rubrum

Current Microbiology, 1988
Four major pencillin-binding proteins (PBPs) were detected in membranes ofRhodospirillum rubrum labeled with radioiodinated penicillin X. These PBPs were localized primarily in the cytoplasmic membrane of aerobic cells, which had a higher content of PBPs relative to protein than did the outer membrane or a hybrid fraction containing both cytoplasmic ...
Charles R. Myers, Mary Lynne Perille Collins   +1 more
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Penicillin-binding proteins inStreptococcus mitis

Current Microbiology, 1992
The penicillin-binding protein (PBP) profiles of penicillin-susceptible and-resistant clinical isolates ofStreptococcus mitis varied even with strains with similar minimal inhibitory concentrations (MICs).S. mitis NCTC 10712 was used as a DNA recipient to investigate PBP alterations which could occur as a result of spontaneous mutation and intra- and ...
Elsa Potgieter, Hendrik J. Koornhof, Lynda J. Chalkley   +2 more
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Purification of Streptococcus faecium penicillin binding protein 5, a multifunctional penicillin-binding protein.

Microbiologica, 1986
Penicillin-binding protein 5 of Streptococcus faecium has been solubilized and partially separated from other membrane proteins by covalent affinity chromatography. PBP 5 was successively purified to homogeneity by resolution on SDS-polyacrylamide gel, elution and renaturation of penicillin-binding activity.
A. Grossato, Y. R. Cheng, E. Tonin, P. Jacques, FONTANA, Roberta   +4 more
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Penicillin-Binding Proteins of Gram-Negative Bacteria

Clinical Infectious Diseases, 1988
beta-Lactam antibiotics exert their antibacterial effects by inactivating the high-molecular-weight penicillin-binding proteins (PBPs) that are responsible for the final stages of peptidoglycan biosynthesis. The availability of the amino acid sequences of several low-molecular-weight PBPs, high-molecular-weight PBPs, and active-site serine beta ...
B G, Spratt, K D, Cromie
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A Method to Assay Penicillin-Binding Proteins

2008
Key enzymes that assemble the bacterial cell wall are also the target of the Beta-lactam class of antibiotics. The covalent binding of labeled penicillin to these proteins has been used in numerous studies in drug discovery, antibiotic mechanisms of action and resistance, and cell wall physiology.
Michael J, Pucci, Thomas J, Dougherty
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Penicillin-Binding Protein 5 of Escherichia coli

2013
Refereed/Peer ...
Malika Kumarasiri, Jed F. Fisher, Shahriar Mobashery   +2 more
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Penicillin-binding Protein

2006
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Penicillin-binding Proteins

RCSB Protein Data Bank, 2002
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Penicillin Binding Protein

RCSB Protein Data Bank
Gauri Patel, Helen Gao
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