Penicillin Resistance of Nonvaccine Type Pneumococcus before and after PCV13 Introduction, United States [PDF]
Introduction of 13-valent pneumococcal conjugate vaccine in the United States was not associated with a significant change in prevalence of penicillin resistance in nonvaccine type serotypes because of the variable success of highly resistant serotypes ...
Cheryl P. Andam +5 more
doaj +3 more sources
Loss of Pde1 function acts as an evolutionary gateway to penicillin resistance in Streptococcus pneumoniae. [PDF]
Significance Streptococcus pneumoniae is an important bacterial pathogen responsible for many serious infections worldwide. Infections are often treated with penicillin antibiotics.
Kobras CM +8 more
europepmc +2 more sources
: Staphylococcus aureus is a major pathogen in humans and animals. In cattle, it is one of the most important agents of mastitis, causing serious costs in the dairy industry.
I. Ivanovic +6 more
doaj +2 more sources
Effects of Pneumococcal Conjugate Vaccine on Genotypic Penicillin Resistance and Serotype Changes, Japan, 2010-2017. [PDF]
To clarify year-to-year changes in capsular serotypes, resistance genotypes, and multilocus sequence types of Streptococcus pneumoniae, we compared isolates collected from patients with invasive pneumococcal disease before and after introductions of 7 ...
Ubukata K +9 more
europepmc +2 more sources
The effect of MurM and a branched cell wall structure on penicillin resistance in Streptococcus pneumoniae [PDF]
The aminoacyltransferase MurM is an important penicillin resistance determinant in Streptococcus pneumoniae. This enzyme attaches a serine or alanine to the side chain of lysine, the third residue of the pentapeptide of lipid II, resulting in branched ...
Ragnhild Sødal Gjennestad +7 more
doaj +2 more sources
Association between treatment failure in patients with early syphilis and penicillin resistance-related gene mutations of Treponema pallidum: Protocol for a multicentre nested case–control study [PDF]
BackgroundThe widespread occurrence of syphilis remains a global public health problem. Although penicillin has been recommended as the first-line therapy for syphilis for more than 70 years, treatment failure occurs in 10–20% of patients with early ...
Hong-Fei Mi +5 more
doaj +2 more sources
Penicillin-Binding Proteins in Streptococcus agalactiae and Their Association with Reduced Penicillin Susceptibility: An Overview [PDF]
Streptococcus agalactiae are bacteria that can cause a range of infections, some of them life-threatening. Currently, antimicrobial resistance has become a global problem that puts public health at risk.
Leonardo Nagao Ferreira +3 more
doaj +2 more sources
Analysis of Whole-Genome Sequences for the Prediction of Penicillin Resistance and β-Lactamase Activity in
Penicillin (PEN) is a low-cost option for anthrax treatment, but naturally occurring resistance has been reported. β-Lactamase expression (bla1, bla2) in Bacillus anthracis is regulated by a sigma factor (SigP) and its cognate anti-sigma factor (RsiP ...
A. S. Gargis +11 more
doaj +4 more sources
Surveillance of nasopharyngeal pneumococcus has proven to be a valuable tool for the monitoring of antibiotic resistance. We reviewed the latest information on colonization rate and penicillin resistance by making a MEDLINE search, using the terms ...
Déa M. Cardozo +3 more
doaj +2 more sources
Penicillin dust exposure and penicillin resistance among pharmaceutical workers in Tehran, Iran. [PDF]
Farshad AA +4 more
europepmc +2 more sources

