Penicillin Resistance of Nonvaccine Type Pneumococcus before and after PCV13 Introduction, United States [PDF]
Introduction of 13-valent pneumococcal conjugate vaccine in the United States was not associated with a significant change in prevalence of penicillin resistance in nonvaccine type serotypes because of the variable success of highly resistant serotypes ...
Cheryl P. Andam+5 more
doaj +3 more sources
Antimicrobial Resistance with Streptococcus pneumoniae in the United States, 1997–98 [PDF]
From November 1997 to April 1998, 1,601 clinical isolates of Streptococcus pneumoniae were obtained from 34 U.S. medical centers. The overall rate of strains showing resistance to penicillin was 29.5%, with 17.4% having intermediate resistance. Multidrug
Gary V. Doern+4 more
doaj +5 more sources
Association between treatment failure in patients with early syphilis and penicillin resistance-related gene mutations of Treponema pallidum: Protocol for a multicentre nested case–control study [PDF]
BackgroundThe widespread occurrence of syphilis remains a global public health problem. Although penicillin has been recommended as the first-line therapy for syphilis for more than 70 years, treatment failure occurs in 10–20% of patients with early ...
Hong-Fei Mi+5 more
doaj +2 more sources
Long-term effects of penicillin resistance and fitness cost on pneumococcal transmission dynamics in a developed setting [PDF]
Background: The increasing prevalence of penicillin non-susceptible pneumococci (PNSP) throughout the world threatens successful treatment of infections caused by this important bacterial pathogen. The rate at which PNSP clones spread in the community is
Diana Tilevik
doaj +2 more sources
Clinical outcome of pneumococcal meningitis during the emergence of pencillin-resistant
Background Prior to the availability of generic third-generation cephalosporins, penicillins were widely used for treatment of pneumococcal meningitis in developing countries despite concerns about rising levels of penicillin resistance among ...
Gouveia Edilane L+11 more
doaj +4 more sources
Analysis of Whole-Genome Sequences for the Prediction of Penicillin Resistance and β-Lactamase Activity in
Penicillin (PEN) is a low-cost option for anthrax treatment, but naturally occurring resistance has been reported. β-Lactamase expression (bla1, bla2) in Bacillus anthracis is regulated by a sigma factor (SigP) and its cognate anti-sigma factor (RsiP ...
A. S. Gargis+11 more
doaj +4 more sources
Sub-inhibitory concentrations of vancomycin prevent quinolone-resistance in a penicillin-resistant isolate of Streptococcus pneumoniae [PDF]
BACKGROUND: The continuous spread of penicillin-resistant pneumococci represents a permanent threat in the treatment of pneumococcal infections, especially when strains show additional resistance to quinolones.
Cottagnoud, Marianne+5 more
core +5 more sources
Penicillin Resistance in Gonorrhoea [PDF]
A. J. King
openalex +4 more sources
Penicillin allergy as an instrumental variable for estimating antibiotic effects on resistance [PDF]
Antibiotic resistance is influenced by prior antibiotic use, but precise causal estimates are limited. This study uses penicillin allergy as an instrumental variable (IV) to estimate the causal effect of antibiotics on resistance.
Yaki Saciuk+3 more
doaj +2 more sources
Penicillin resistance in pneumococci [PDF]
D. Felmingham
openalex +4 more sources