Results 1 to 10 of about 486,095 (301)

The effect of MurM and a branched cell wall structure on penicillin resistance in Streptococcus pneumoniae [PDF]

Journal of Bacteriology
The aminoacyltransferase MurM is an important penicillin resistance determinant in Streptococcus pneumoniae. This enzyme attaches a serine or alanine to the side chain of lysine, the third residue of the pentapeptide of lipid II, resulting in branched ...
Ragnhild Sødal Gjennestad, Maria Victoria Heggenhougen, Anja Ruud Winther, Johanne Moldstad, Vegard Eldholm, Morten Kjos, Leiv Sigve Håvarstein, Daniel Straume   +7 more
doaj   +2 more sources

Association between treatment failure in patients with early syphilis and penicillin resistance-related gene mutations of Treponema pallidum: Protocol for a multicentre nested case–control study [PDF]

Frontiers in Medicine, 2023
BackgroundThe widespread occurrence of syphilis remains a global public health problem. Although penicillin has been recommended as the first-line therapy for syphilis for more than 70 years, treatment failure occurs in 10–20% of patients with early ...
Hong-Fei Mi, Xu Shen, Xiao-Qing Chen, Xiao-Luo Zhang, Wu-Jian Ke, Yao Xiao   +5 more
doaj   +2 more sources

Penicillin Resistance of Nonvaccine Type Pneumococcus before and after PCV13 Introduction, United States [PDF]

Emerging Infectious Diseases, 2017
Introduction of 13-valent pneumococcal conjugate vaccine in the United States was not associated with a significant change in prevalence of penicillin resistance in nonvaccine type serotypes because of the variable success of highly resistant serotypes ...
Cheryl P. Andam, Colin J. Worby, Ryan Gierke, Lesley McGee, Tamara Pilishvili, William P. Hanage   +5 more
doaj   +2 more sources

Analysis of Whole-Genome Sequences for the Prediction of Penicillin Resistance and β-Lactamase Activity in Bacillus anthracis [PDF]

mSystems, 2018
Penicillin (PEN) is a low-cost option for anthrax treatment, but naturally occurring resistance has been reported. β-Lactamase expression (bla1, bla2) in Bacillus anthracis is regulated by a sigma factor (SigP) and its cognate anti-sigma factor (RsiP ...
A. S. Gargis, H. P. McLaughlin, A. B. Conley, C. Lascols, P. A. Michel, J. E. Gee, C. K. Marston, C. B. Kolton, L. M. Rodriguez-R, A. R. Hoffmaster, L. M. Weigel, D. Sue   +11 more
doaj   +4 more sources

Serogroup Y Clonal Complex 23 Meningococcus in China Acquiring Penicillin Resistance from Commensal Neisseria lactamica Species. [PDF]

Antimicrob Agents Chemother, 2022
Shao Y, Chen M, Luo J, Li D, Yuan L, Yang X, Wang M, Chen M, Guo Q.   +8 more
europepmc   +3 more sources

Impact of the revised penicillin susceptibility breakpoints for Streptococcus pneumoniae on antimicrobial resistance rates of meningeal and non-meningeal pneumococcal strains

Annals of Saudi Medicine, 2013
BACKGROUND AND OBJECTIVES: In January 2008, the Clinical Laboratory Standard Institute (CLSI) revised the Streptococcus pneumoniae breakpoints for penicillin to define the susceptibility of meningeal and nonmeningeal isolates.
Badria R. Al-Waili, Sahar Al-Thawadi, Sami Al Hajjar   +2 more
doaj   +2 more sources

Study of Invasive Pneumococcal Infection in Adults with Reference to Penicillin Resistance.

J Lab Physicians, 2017
Muley VA, Ghadage DP, Yadav GE, Bhore AV.   +3 more
europepmc   +2 more sources

Beta-Lactamase Repressor BlaI Modulates Staphylococcus aureus Cathelicidin Antimicrobial Peptide Resistance and Virulence. [PDF]

, 2015
BlaI is a repressor of BlaZ, the beta-lactamase responsible for penicillin resistance in Staphylococcus aureus. Through screening a transposon library in S.
Gallo, Richard L, Haste, Nina M, Kristian, Sascha A, Meharena, Hiruy S, Nizet, Victor, Olson, Joshua, Pence, Morgan A   +6 more
core   +18 more sources

Penicillin resistance in bovine Staphylococcus aureus: Genomic evaluation of the discrepancy between phenotypic and molecular test methods

Journal of Dairy Science, 2023
: Staphylococcus aureus is a major pathogen in humans and animals. In cattle, it is one of the most important agents of mastitis, causing serious costs in the dairy industry.
I. Ivanovic, R. Boss, A. Romanò, E. Guédon, Y. Le-Loir, M. Luini, H.U. Graber   +6 more
doaj   +1 more source

Meningococcal Antibiotic Resistance: Molecular Characterization of Isolates from Patients with Invasive Meningococcal Disease (IMD) in Greece

Antibiotics, 2023
For effective case management and chemoprophylaxis of Invasive Meningococcal Disease (IMD), prompt antibiotic treatment is required. N. meningitidis is usually susceptible to antibiotics, but reduced susceptibility to penicillin, ciprofloxacin, and ...
Ioanna Spiliopoulou, Athanasia Xirogianni, Stelmos Simantirakis, Georgina Tzanakaki   +3 more
doaj   +1 more source