Results 1 to 10 of about 442,503 (251)

Long-term effects of penicillin resistance and fitness cost on pneumococcal transmission dynamics in a developed setting [PDF]

open access: yesInfection Ecology & Epidemiology, 2016
Background: The increasing prevalence of penicillin non-susceptible pneumococci (PNSP) throughout the world threatens successful treatment of infections caused by this important bacterial pathogen. The rate at which PNSP clones spread in the community is
Diana Tilevik
doaj   +2 more sources

Association between treatment failure in patients with early syphilis and penicillin resistance-related gene mutations of Treponema pallidum: Protocol for a multicentre nested case–control study [PDF]

open access: yesFrontiers in Medicine, 2023
BackgroundThe widespread occurrence of syphilis remains a global public health problem. Although penicillin has been recommended as the first-line therapy for syphilis for more than 70 years, treatment failure occurs in 10–20% of patients with early ...
Hong-Fei Mi   +5 more
doaj   +2 more sources

Penicillin Resistance of Nonvaccine Type Pneumococcus before and after PCV13 Introduction, United States [PDF]

open access: yesEmerging Infectious Diseases, 2017
Introduction of 13-valent pneumococcal conjugate vaccine in the United States was not associated with a significant change in prevalence of penicillin resistance in nonvaccine type serotypes because of the variable success of highly resistant serotypes ...
Cheryl P. Andam   +5 more
doaj   +2 more sources

Analysis of Whole-Genome Sequences for the Prediction of Penicillin Resistance and β-Lactamase Activity in Bacillus anthracis [PDF]

open access: yesmSystems, 2018
Penicillin (PEN) is a low-cost option for anthrax treatment, but naturally occurring resistance has been reported. β-Lactamase expression (bla1, bla2) in Bacillus anthracis is regulated by a sigma factor (SigP) and its cognate anti-sigma factor (RsiP ...
A. S. Gargis   +11 more
doaj   +4 more sources

Penicillin resistance in pneumococci [PDF]

open access: bronzeJournal of Antimicrobial Chemotherapy, 2000
David Felmingham   +3 more
openaire   +4 more sources

Meningococcal Antibiotic Resistance: Molecular Characterization of Isolates from Patients with Invasive Meningococcal Disease (IMD) in Greece

open access: yesAntibiotics, 2023
For effective case management and chemoprophylaxis of Invasive Meningococcal Disease (IMD), prompt antibiotic treatment is required. N. meningitidis is usually susceptible to antibiotics, but reduced susceptibility to penicillin, ciprofloxacin, and ...
Ioanna Spiliopoulou   +3 more
doaj   +1 more source

Beta-Lactamase Repressor BlaI Modulates Staphylococcus aureus Cathelicidin Antimicrobial Peptide Resistance and Virulence. [PDF]

open access: yes, 2015
BlaI is a repressor of BlaZ, the beta-lactamase responsible for penicillin resistance in Staphylococcus aureus. Through screening a transposon library in S.
Gallo, Richard L   +6 more
core   +10 more sources

Restricted Sequence Variation in Streptococcus pyogenes Penicillin Binding Proteins

open access: yesmSphere, 2020
A recent clinical report has linked Streptococcus pyogenes β-lactam antibiotic resistance to mutation in the penicillin binding protein (PBP) PBP2x. To determine whether this is an isolated case or reflects a broader prevalence of mutations that might ...
Andrew Hayes   +4 more
doaj   +1 more source

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