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Antibiotic resistance in the environment, with particular reference to MRSA [PDF]
The introduction of β-lactam antibiotics (penicillins and cephalosporins) in the 1940s and 1950s probably represents the most dramatic event in the battle against infection in human medicine.
Aarestrup+171 more
core +1 more source
Penicillin Resistant Staphylococci
Summary(1) In a study of the susceptibility of 115 strains of staphylococci to penicillin 16 or 13.9% were found to be resistant. (2) All strains resistant to penicillin produced penicillinase; none of the susceptible strains had this property. (3) Many of the penicillinase-producing staphylococci produce coagulase indicating the importance of the ...
Catherine C. Dietz, Amedeo Bondi
openaire +3 more sources
Effect of Penicillin Resistance ofStreptococcus pneumoniaeon the Presentation, Prognosis, and Treatment of Pneumococcal Endocarditis in Adults [PDF]
We performed a clinical study of pneumococcal endocarditis (PE) in adults at 15 major Spanish hospitals during a 21-year period (1978-1998). During this time, 63 patients had PE due to Streptococcus pneumoniae diagnosed. Of the 63 isolates recovered from
Estebán Martínez+11 more
openalex +2 more sources
The most frequent reason for antimicrobial use in dairy herds is mastitis and knowledge about mastitis-causing pathogens and their antimicrobial susceptibility should guide treatment decisions.
Suvi Taponen+2 more
doaj +1 more source
Clinical resistance and decreased susceptibility in Streptococcus suis isolates from clinically healthy fattening pigs [PDF]
Streptococcus suis (S. suis) has often been reported as an important swine pathogen and is considered as a new emerging zoonotic agent. Consequently, it is important to be informed on its susceptibility to antimicrobial agents.
Boyen, Filip+5 more
core +1 more source
Prompt Engineering for Transformer-based Chemical Similarity Search Identifies Structurally Distinct Functional Analogues [PDF]
Chemical similarity searches are widely used in-silico methods for identifying new drug-like molecules. These methods have historically relied on structure-based comparisons to compute molecular similarity. Here, we use a chemical language model to create a vector-based chemical search.
arxiv +1 more source
In this study, penicillin, oxacillin, and macrolide-lincosamide-streptogramin (MLS) resistance in S. aureus strains that were isolated from bovine mastitis cases, and human patients were investigated.
Gulaydin Ozgul+4 more
doaj +1 more source
β-Lactam antibiotics are the drugs of choice to treat pneumococcal infections. The spread of β-lactam-resistant pneumococci is a major concern in choosing an effective therapy for patients.
Yuan Li+10 more
semanticscholar +1 more source
Background Pneumococcal diseases remain a major cause of morbidity and mortality worldwide. Updated data on drug-resistance from different populations may be important to recognize changes in disease patterns.
Raga-Luria Xavier+8 more
doaj +1 more source
Resistance to β-Lactams in Neisseria ssp Due to Chromosomally Encoded Penicillin-Binding Proteins
Neisseria meningitidis and Neisseria gonorrhoeae are human pathogens that cause a variety of life-threatening systemic and local infections, such as meningitis or gonorrhoea.
A. Zapun, C. Morlot, M. Taha
semanticscholar +1 more source