Results 51 to 60 of about 3,443,339 (411)

Evolving Antibiotic Resistance in Group B Streptococci Causing Invasive Infant Disease: 1970–2021 [PDF]

open access: yes, 2022
BACKGROUND: We sought to define the frequency of antibiotic resistance over time in a collection of invasive GBS isolates derived from infant early-onset disease (EOD), late-onset disease (LOD), and late-late onset disease (LLOD).
Baker, Carol J   +7 more
core   +2 more sources

An automatic approach to explore multi-reaction mechanism for medium-sized bimolecular reactions via collision dynamics simulations and transition state searches [PDF]

open access: yesarXiv, 2021
We develop a broadly-applicable computational method for the automatic exploration of the bimolecular multi-reaction mechanism. The current methodology mainly involves the high-energy Born-Oppenheimer molecular dynamics (BOMD) simulation and the successive reaction pathway construction.
arxiv  

Convection shapes the trade-off between antibiotic efficacy and the selection for resistance in spatial gradients [PDF]

open access: yes, 2017
Since penicillin was discovered about 90 years ago, we have become used to using drugs to eradicate unwanted pathogenic cells. However, using drugs to kill bacteria, viruses or cancer cells has the serious side effect of selecting for mutant types that survive the drug attack.
arxiv   +1 more source

Real-time Monitoring of Functional Data [PDF]

open access: yesarXiv, 2022
With the rise of Industry 4.0, huge amounts of data are now generated that are apt to be modelled as functional data. In this setting, standard profile monitoring methods aim to assess the stability over time of a completely observed functional quality characteristic. However, in some practical situations, evaluating the process state in real-time, i.e.
arxiv  

Impact of the revised penicillin susceptibility breakpoints for Streptococcus pneumoniae on antimicrobial resistance rates of meningeal and non-meningeal pneumococcal strains

open access: yesAnnals of Saudi Medicine, 2013
BACKGROUND AND OBJECTIVES: In January 2008, the Clinical Laboratory Standard Institute (CLSI) revised the Streptococcus pneumoniae breakpoints for penicillin to define the susceptibility of meningeal and nonmeningeal isolates.
Badria R. Al-Waili   +2 more
doaj   +1 more source

Transferable beta-lactamase. A new mechanism for in vitro penicillin resistance in Streptococcus faecalis.

open access: yesJournal of Clinical Investigation, 1983
Although enterococci are relatively resistant to penicillin, the mechanism of resistance is largely unknown and enzymatic inactivation does not play a role.
Barbara   +3 more
semanticscholar   +1 more source

Detection of pbp2b and ermB genes in clinical isolates of Streptococcus pneumoniae

open access: yesJournal of Infection in Developing Countries, 2008
Background: Streptococcus pneumoniae is a major human pathogen. The emergence of penicillin resistant strains since the 1970s has been life threatening and the evolution of the bacteria have enabled itself to develop resistance to many other antibiotics ...
Navindra Kumari,1 Parasakthi Navaratnam,2 Shamala Devi Sekaran.1
doaj   +3 more sources

Antibiotic susceptibility/resistant gene profiles of Group B streptococci isolates from pregnant women in a tertiary institution in Nigeria

open access: yesJournal of Clinical Sciences, 2016
Background: Penicillin is recommended as the first-line agent for intrapartum antibiotic prophylaxis (IAP). Although Group B Streptococcus (GBS) strains are generally susceptible to penicillin with only occasional resistance, they show varying resistance
Charles J Elikwu   +3 more
doaj   +1 more source

Sampling To Improve Predictions For Underrepresented Observations In Imbalanced Data [PDF]

open access: yesarXiv, 2021
Data imbalance is common in production data, where controlled production settings require data to fall within a narrow range of variation and data are collected with quality assessment in mind, rather than data analytic insights. This imbalance negatively impacts the predictive performance of models on underrepresented observations. We propose sampling
arxiv  

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