Results 21 to 30 of about 204,146 (354)
The antiinflammatory and electrophysiological effects of fingolimod on penicillin-induced rats
Background The fact that inflammation triggers epileptic seizures brings to mind the antiepileptic properties of anti-inflammatory drugs. Objective To investigate the electrophysiological and anti-inflammatory effects of fingolimod on an ...
Canan Akünal Türel+4 more
doaj +1 more source
In clinical microbiology, matrix-assisted laser desorption ionization–time-of-flight mass spectrometry (MALDI-TOF MS) is frequently employed for rapid microbial identification.
Chia-Ru Chung+6 more
doaj +1 more source
Staphylococcus aureus methicillin-resistance mechanisms [PDF]
Background/Aim. In many hospitals in the world and in our country, the spread of methicillin-resistant Staphylococcus aureus (MRSA) is so wide that nowdays vancomycin is recommended for empiric treatment of staphylococcal life threatening infections ...
Petrović-Jeremić Ljiljana+3 more
doaj +1 more source
Pitfalls in the Immunochemical Determination of β-Lactam Antibiotics in Water
Contamination of waters with pharmaceuticals is an alarming problem as it may support the evolution of antimicrobial resistance. Therefore, fast and cost-effective analytical methods for potential on-site analysis are desired in order to control the ...
Alexander Ecke, Rudolf J. Schneider
doaj +1 more source
Documented penicillin allergies have been associated with an increased risk of adverse outcomes. The goal of this project was to assess the effectiveness and feasibility of a pharmacist-led penicillin allergy “de-labeling” process that does not involve ...
You-Chan Song+3 more
doaj +1 more source
Delabelling multiple antibiotic allergy: Practical issues
With the growing incidence of multi-drug resistant organisms, delabelling incorrect antibiotic allergies has become an integral part of antimicrobial stewardship worldwide.
Philip Hei Li, Bernard Yu-Hor Thong
doaj +1 more source
Prompt Engineering for Transformer-based Chemical Similarity Search Identifies Structurally Distinct Functional Analogues [PDF]
Chemical similarity searches are widely used in-silico methods for identifying new drug-like molecules. These methods have historically relied on structure-based comparisons to compute molecular similarity. Here, we use a chemical language model to create a vector-based chemical search.
arxiv +1 more source
Perioperative infection prophylaxis and risk factor impact in colon surgery [PDF]
Background: A prospective observational study was undertaken in 2,481 patients undergoing elective colon resection in 114 German centers to identify optimal drug and dosing modalities and risk factors for postoperative infection.
Kohler, L.+5 more
core +1 more source
The rate of invasive group B Streptococcus (GBS) infections is steadily increasing, particularly in older persons and in adults with diabetes and other comorbidities.
Corinne Ruppen+8 more
doaj +1 more source
Association between Antibiotic Prescribing in Pregnancy and Cerebral Palsy or Epilepsy in Children Born at Term: A Cohort Study Using The Health Improvement Network. [PDF]
Between 19%-44% pregnant women are prescribed antibiotics during pregnancy. A single, large randomised-controlled-trial (ORACLE Childhood Study II) found an increased risk of childhood cerebral palsy and possibly epilepsy following prophylactic ...
Gilbert, R, Meeraus, WH, Petersen, I
core +7 more sources