Results 21 to 30 of about 70,893 (311)

Drugs That Changed Society: History and Current Status of the Early Antibiotics: Salvarsan, Sulfonamides, and β-Lactams

Molecules, 2021
The appearance of antibiotic drugs revolutionized the possibilities for treatment of diseases with high mortality such as pneumonia, sepsis, plaque, diphtheria, tetanus, typhoid fever, and tuberculosis.
Søren Brøgger Christensen
doaj   +1 more source

ANTIBACTERIAL THERAPY OF INFECTIVE ENDOCARDITIS

Alʹmanah Kliničeskoj Mediciny, 2016
The article analyzes the influence of infective endocarditis etiology on the clinical course of the disease. The role of Staphylococci as common pathogens is emphasized. Streptococci have faded in importance, though, streptococcal endocarditis is still a
M. A. Gurevich, N. A. Kuz’menko
doaj   +1 more source

Retrospective analysis of adverse drug reaction reporting forms associated with penicillin family antibiotics (pcne-drp 9.0) based on drug-related approach

Фармация и фармакология (Пятигорск), 2020
A widespread use of β-lactam antibiotics such as penicillins in practical medicine, and its authorized use in special categories of patients (e.g. children, pregnant and lactating women, the elderly) requires a critical investigation of their safety as ...
A. V. Matveev, A. E. Krasheninnikov, E. A. Egorova, E. I. Koniaeva   +3 more
doaj   +1 more source

Pharmacokinetics, optimal dosages and withdrawal time of amoxicillin in Nile tilapia (Oreochromis niloticus) reared at 25 and 30 °C

Veterinary Quarterly
Knowledge of amoxicillin (AMX) pharmacokinetics (PK) and tissue residues in fish, which is necessary for prudent drug use, remains limited. The study aimed to explore the PK characteristics of AMX in Nile tilapia (Oreochromis niloticus) reared at 25 and ...
Tirawat Rairat, Yi-Ping Lu, Wan-Cih Ho, Hual-Jhong Ke, Chi-Chung Chou   +4 more
doaj   +1 more source

Medication Errors Associated with the Use of Penicillins [PDF]

Клиническая микробиология и антимикробная химиотерапия, 2016
Objective. To determine the prevalence of medication errors associated with the use of penicillin-group antibiotics through analysis of national spontaneous reporting database. Materials and Methods. The study involved examination of 1123 spontaneous
Kuzmina A.V., Polivanov V.A., Asetskaya I.L., Zyryanov S.K.   +3 more
doaj  

β-Lactam Allergy and Cross-Reactivity: A Clinician’s Guide to Selecting an Alternative Antibiotic

Journal of Asthma and Allergy, 2021
Cristiano Caruso,1 Rocco Luigi Valluzzi,2 Stefania Colantuono,1 Francesco Gaeta,1 Antonino Romano3,4 1Allergy Unit, Columbus Hospital, Fondazione Policlinico A.
Caruso C, Valluzzi RL, Colantuono S, Gaeta F, Romano A   +4 more
doaj  

Penicillins: update for clinical practice

Revista Médica de Minas Gerais, 2023
Introduction: The discovery of penicillins is one of the milestones in the history of health care. These drugs are among the most prescribed antimicrobials in the world, with applicability even today in different diseases and infectious complications ...
Rodrigo Siqueira-Batista, Marcos Mauricio Reis Alves, Márcio Antônio Gaspar Lara, Andréia Patrícia Gomes, Jorge Luiz Dutra Gazineo, Luciene Muniz Braga   +5 more
doaj   +1 more source

Crosstalk between the ribosome quality control‐associated E3 ubiquitin ligases LTN1 and RNF10

FEBS Letters, EarlyView.
Loss of the E3 ligase LTN1, the ubiquitin‐like modifier UFM1, or the deubiquitinating enzyme UFSP2 disrupts endoplasmic reticulum–ribosome quality control (ER‐RQC), a pathway that removes stalled ribosomes and faulty proteins. This disruption may trigger a compensatory response to ER‐RQC defects, including increased expression of the E3 ligase RNF10 ...
Yuxi Huang, Satoshi Hashimoto, Sota Ito, Chisato Kikuguchi, Miho Hoshi, Kiyoshi Yamaguchi, Yoichi Furukawa, Toru Suzuki, Toshifumi Inada   +8 more
wiley   +1 more source

Causal treatment of acute and chronic tonsillar disease

Медицинский совет, 2014
Bacterial lesion in the oropharynx is a pressing issue in otorhinolaryngology. After flu and acute respiratory infections, sore throat and chronic tonsillitis are the most common human diseases, the prevalence of which, as well as a high probability of a
A. I. Kryukov, A. V. Gurov, G. N. Izotova, O. A. Guseva   +3 more
doaj   +1 more source

Multiple ETS family transcription factors bind mutant p53 via distinct interaction regions

FEBS Letters, EarlyView.
Mutant p53 gain‐of‐function is thought to be mediated by interaction with other transcription factors. We identify multiple ETS transcription factors that can bind mutant p53 and found that this interaction can be promoted by a PXXPP motif. ETS proteins that strongly bound mutant p53 were upregulated in ovarian cancer compared to ETS proteins that ...
Stephanie A. Metcalf, Nicholas F. Downing, Kaitlyn M. Mills, Samuel C. Metcalfe, Alexander E. Kritzer, Lindsey D. Mayo, Peter C. Hollenhorst   +6 more
wiley   +1 more source