Dose optimization of β-lactams antibiotics in pediatrics and adults: A systematic review
Background: β-lactams remain the cornerstone of the empirical therapy to treat various bacterial infections. This systematic review aimed to analyze the data describing the dosing regimen of β-lactams.Methods: Systematic scientific and grey literature ...
Abdul Haseeb +18 more
doaj +1 more source
Antimicrobial use in European acute care hospitals: results from the second point prevalence survey (PPS) of healthcare-associated infections and antimicrobial use, 2016 to 2017 [PDF]
Antimicrobial agents used to treat infections are life-saving. Overuse may result in more frequent adverse effects and emergence of multidrug-resistant microorganisms.
Aghdassi, S. +69 more
core +7 more sources
Identification of New Drug Candidates Against \u3cem\u3eBorrelia burgdorferi\u3c/em\u3e Using High-Throughput Screening [PDF]
Lyme disease is the most common zoonotic bacterial disease in North America. It is estimated that .300,000 cases per annum are reported in USA alone. A total of 10%–20% of patients who have been treated with antibiotic therapy report the recrudescence of
Babar, Mustafeez Mujtaba +9 more
core +3 more sources
Misconceptions about Antibiotics in general practice
No abstract available.
Johan Dippenaar
doaj +1 more source
Antibacterial prophylaxis of surgical site infections in oral surgery: not only and not always systemic antibiotics [PDF]
Antibacterial prophylaxis is a set of treatment measures, including antibiotic prophylaxis, under surgeon’s responsibility. If local measures are always to be applied, antibiotic prophylaxis administration needs a careful case selection in order to avoid
Pippi, Roberto
core +1 more source
Knowledge of amoxicillin (AMX) pharmacokinetics (PK) and tissue residues in fish, which is necessary for prudent drug use, remains limited. The study aimed to explore the PK characteristics of AMX in Nile tilapia (Oreochromis niloticus) reared at 25 and ...
Tirawat Rairat +4 more
doaj +1 more source
Fungi - an Amalgam of Toxins and Antibiotics: a Mini- Review [PDF]
Fungi are eukaryotes with many functions. Earlier, fungi were classified in the plant kingdom but were later classified as a separate kingdom due to their unique cell walls. Fungi are heterotrophs like animals and are more closely related to animals. The
Ahmed, M. (Muddassir) +3 more
core
Consumption of antibiotics within ambulatory care in Malta [PDF]
Background: Antibiotic use is recognised as the most important driver for the development of antimicrobial resistance in community pathogens. Surveillance is therefore critical for improvement programmes.
Borg, Michael Angelo, Zarb, Peter
core
Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz +11 more
wiley +1 more source
Penicillins: update for clinical practice
Introduction: The discovery of penicillins is one of the milestones in the history of health care. These drugs are among the most prescribed antimicrobials in the world, with applicability even today in different diseases and infectious complications ...
Rodrigo Siqueira-Batista +5 more
doaj +1 more source

