Results 41 to 50 of about 170,743 (345)

Spectrophotometric method for assay of penicillins

, 1987
Ninhydrin in 0.2 M citrate buffer (pH 5) containing SnCl2 is proposed as a new reagent for Spectrophotometric determination of penicillins and analysis of their pharmaceutical formulations.
Hiremath, R.C., Mayanna, S.M.
core   +1 more source

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

FEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz, Mihály Mérey, Rebeka Vásárhelyi, Ramóna Pék, Victor Imburchia, László Henn, Adrián Kószó, Nicholas D. Lakin, Ivan Ahel, Sébastien Huet, Ágnes Czibula, Gyula Timinszky   +11 more
wiley   +1 more source

Penicillins: update for clinical practice

Revista Médica de Minas Gerais, 2023
Introduction: The discovery of penicillins is one of the milestones in the history of health care. These drugs are among the most prescribed antimicrobials in the world, with applicability even today in different diseases and infectious complications ...
Rodrigo Siqueira-Batista, Marcos Mauricio Reis Alves, Márcio Antônio Gaspar Lara, Andréia Patrícia Gomes, Jorge Luiz Dutra Gazineo, Luciene Muniz Braga   +5 more
doaj   +1 more source

An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane

FEBS Letters, EarlyView.
Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa, Akira Hattori, Masafumi Tsujimoto, Toshihide Kobayashi   +3 more
wiley   +1 more source

Causal treatment of acute and chronic tonsillar disease

Медицинский совет, 2014
Bacterial lesion in the oropharynx is a pressing issue in otorhinolaryngology. After flu and acute respiratory infections, sore throat and chronic tonsillitis are the most common human diseases, the prevalence of which, as well as a high probability of a
A. I. Kryukov, A. V. Gurov, G. N. Izotova, O. A. Guseva   +3 more
doaj   +1 more source

Physicochemical Properties of Some Semisynthetic Penicillins

, 1972
Variation in the structure of the sidechain of penicillins has been shown to be associated with changes in the physicochemical properties of the substances.
Ian M. Rollo
core   +1 more source

Septin 9 PB domains coordinate centrosome positioning and microtubule acetylation to control epithelial polarity

FEBS Letters, EarlyView.
Septin 9 polybasic domains couple phosphoinositide‐rich membrane binding to centrosome positioning, Golgi organization, and microtubule acetylation to control epithelial polarity. Their loss disrupts this axis, causing centrosome mispositioning, Golgi fragmentation, reduced microtubule acetylation, and polarity inversion via upregulation of the ...
Ting ting Cai, Mohyeddine Omrane, Nassima Benzoubir, Didier Samuel, Ama Gassama‐Diagne   +4 more
wiley   +1 more source

Clinical characteristics and risk factors for escalation to anaphylaxis from non‐severe drug hypersensitivity reaction

Clinical and Translational Allergy
Background Drug hypersensitivity reaction (DHR) poses significant challenges in clinical practice, with some patients experiencing more severe reactions upon re‐exposure.
Hyo‐In Rhyou, Sung‐Ryeol Kim, Jae‐Woo Jung, Sae‐Hoon Kim, Ji‐Hyang Lee, Hye Jung Park, Kyung‐Hee Park, Hee‐Sun Park, Eun‐Hee Chung, Gil‐Soon Choi, Sujeong Kim, Min‐Suk Yang, Jung‐Yeon Shim, Young‐Il Koh, Da‐Woon Sim, Jae‐Hyun Lee, Young‐Hee Nam, Hye‐Ryun Kang   +17 more
doaj   +1 more source

The significance of E. coli treatment in perinatal period [PDF]

Hospital Pharmacology, 2016
Introduction: Bacteriuria of pregnancy is a common condition. Case report: Patient, 30-years, pregnant woman. During pregnancy, E. coli infection recurred in 4 times, applied Cephalexin and Ceftriaxone.
Ljubić Aleksandar D., Nikolić Ljubinka I., Stefanović Slobodanka B., Popović Zoran, Bojanić Nebojša N., Anojcić Petar, Marković Srdjan Z., Mijajlović Miloš S., Kastratović Dragana A.   +8 more
doaj   +1 more source

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

Molecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat, Aslihan Kucuk, Omer Erdogan, Samed Ozer, Bensu Kozan, Tugba Cuceli, Erkan Gumus, Evrim Cevik, Ozge Cevik   +8 more
wiley   +1 more source