Results 221 to 230 of about 35,459 (292)

Prioritising research on endocrine disruption in the marine environment: a global perspective

open access: yesBiological Reviews, Volume 101, Issue 2, Page 848-868, April 2026.
ABSTRACT A healthy ocean is a crucial life support system that regulates the global climate, is a source of oxygen and supports major economic activities. A vast and understudied biodiversity from micro‐ to macro‐organisms is integral to ocean health.
Patricia I. S. Pinto   +23 more
wiley   +1 more source

Real‐world persistence and dose titration of GLP‐1 receptor agonists in type 2 diabetes: A UK population‐based cohort study by obesity and cardiovascular disease status

open access: yesDiabetes, Obesity and Metabolism, Volume 28, Issue 4, Page 3386-3395, April 2026.
Abstract Aims Real‐world medication use varies across clinical trial and healthcare settings; therefore, we evaluated GLP‐1 receptor agonist (GLP‐1RA) persistence and dose titration among adults with type 2 diabetes in UK primary care, stratified by agent, obesity status, cardiovascular disease (CVD) history, and sex assigned at birth.
Franziska S. Ulrich   +3 more
wiley   +1 more source

Using Arts‐Based Methods to Involve People Living in Tower Hamlets With Multiple Long‐Term Conditions in the Development of Artificial Intelligence Tools in Healthcare Research

open access: yesHealth Expectations, Volume 29, Issue 2, April 2026.
ABSTRACT Background Including public contributors in the development of artificial intelligence (AI) systems in healthcare research is growing, however, traditional methods of participation fail to engage people from minoritised groups. This work explores how we can utilise art‐based methods to involve the perspectives of those not previously included ...
Elizabeth Remfry   +7 more
wiley   +1 more source

Pembrolizumab Plus Platinum-Based Chemotherapy for Patients With Advanced Penile Cancer: The Nonrandomized HERCULES (LACOG 0218) Clinical Trial.

open access: yesJAMA Oncol
Cotait Maluf F   +16 more
europepmc   +1 more source

Noradrenergic inhibition of definitive POMC neurons through direct and indirect mechanisms

open access: yesJournal of Neuroendocrinology, Volume 38, Issue 4, April 2026.
Norepinephrine and the α2‐adrenoceptor agonist UK 14,304 robustly inhibit definitive arcuate POMC neurons. Direct inhibition is mediated by ADRA2A‐dependent activation of potassium conductances, while additional indirect mechanisms also contribute. In vivo, inducible POMC‐specific Adra2a deletion minimally affects energy balance and modestly impairs ...
Olivier Lavoie   +6 more
wiley   +1 more source

Neutrophil-to-lymphocyte ratio predicts a poor prognosis for penile cancer with an immunosuppressive tumor microenvironment. [PDF]

open access: yesFront Immunol
Tan X   +18 more
europepmc   +1 more source

Evaluating the Efficacy of Polyphenol‐Enriched Plant Extracts and Pathway Modulators in the Bone Marrow to Suppress Breast Cancer Progression

open access: yesThe FASEB Journal, Volume 40, Issue 6, 31 March 2026.
The combined therapy decreased inflammatory and angiogenic signaling and altered bone marrow cell profiles linked to tumor dormancy, indicating a potential approach to limit disease progression and reduce relapse risk in breast cancer. ABSTRACT Disseminated tumor cells (DTCs) in the bone marrow can survive in a dormant state and later reawaken to drive
Hayarpi Javrushyan   +7 more
wiley   +1 more source

Impact of sarcopenia and fat distribution on outcomes in penile cancer. [PDF]

open access: yesSci Rep
Hartmann V   +10 more
europepmc   +1 more source

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