Results 211 to 220 of about 3,009,633 (302)

Pathogenic Variants in HEPACAM Alter Protein Localization and Interactome in Astrocytes of the Developing Mouse Cortex

open access: yesGlia, Volume 74, Issue 11, November 2026.
Pathogenic variants alter hepaCAM protein distribution. Astrocyte‐specific hepaCAM TurboID reveals KCNQ2 as a new interaction partner. Pathogenic variants alter hepaCAM association with key transmembrane proteins. ABSTRACT Megalencephalic leukoencephalopathy with subcortical cysts (MLC) is a rare leukodystrophy characterized by early‐onset macrocephaly,
Robert W. Lewis   +10 more
wiley   +1 more source

Resolution and Quantitation of Ribonucleosides and Deoxyribonucleosides in Digested Genomic DNA by UHPLC–MS/MS

open access: yesBiomedical Chromatography, Volume 40, Issue 10, October 2026.
ABSTRACT Deoxyuridine (dUrd) is often misincorporated into genomic DNA in cancer patients receiving antimetabolite chemotherapy. This activates base excision repair and recruits ataxia telangiectasia‐mutated and Rad3‐related (ATR), which coordinates DNA repair with nucleotide metabolism by facilitating ribonucleotide reductase (RNR) activity ...
Joshua J. Deppas   +5 more
wiley   +1 more source

The 9th Edition of the UICC TNM Classification of Malignant Tumours: Updates and Rationale for Change

open access: yesInternational Journal of Cancer, Volume 159, Issue 7, Page 1588-1601, 1 October 2026.
ABSTRACT The standard for assessing and recording the extent of the tumour, a necessity for most malignancies, is the Tumour Node Metastases (TNM) classification. The Union for International Cancer Control (UICC) TNM committee has defined this since the early 1950s.
James D. Brierley   +8 more
wiley   +1 more source

The Hidden Hazards of Vaping

open access: yesThe Laryngoscope, Volume 136, Issue 10, Page 4333-4335, October 2026.
A 31 year old male presented with a penetrating oropharyngeal injury following a motor vehicle collision and was found to have a retained metallic foreign body suspected to be part of a vape pen. The foreign body was abutting the carotid artery and was removed via a combined transoral and transcervical approach.
Ayaantuu F. Usman, Sobia F. Khaja
wiley   +1 more source

Optimization of Analytical Performances and Routine Laboratory Implementation of NPM1 Mutation Detection by Digital PCR in the Diagnosis and Monitoring of NPM1 ‐Mutated Acute Myeloid Leukemias

open access: yesInternational Journal of Laboratory Hematology, Volume 48, Issue 5, Page 1149-1157, October 2026.
ABSTRACT Introduction Quantification and monitoring of NPM1 mutations represent a key tool in the management of acute myeloid leukemia (AML), offering strong prognostic value and serving as a marker of minimal residual disease (MRD). Digital PCR (dPCR) provides absolute quantification with high sensitivity and specificity, offering advantages over ...
Chloé Ferrari   +10 more
wiley   +1 more source

Exploring advancements in the management of penile cancer in the era of artificial intelligence and machine learning: a narrative review. [PDF]

open access: yesAnn Med Surg (Lond)
Ali RN   +8 more
europepmc   +1 more source

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