Results 61 to 70 of about 5,528 (259)

Large verrucous penis cancer in a young patient in the Brazilian Amazon: Case report and discussion on the region's reality

Urology Case Reports, 2019
Introduction: Penile cancer is a rare malignant tumour top in urology, especially in developed countries or in a favourable cultural habit. However, in developing countries or with a low socio-economic population, the incidence increases considerably, as
Francisco Marcos da Silva Barroso, Cristiano Silveira Paiva, Flavio Antunes de Sousa, Gualter Ferreira de Andrade Júnior, Roger Arthur da Cunha Alves, Ketlen Gomes da Costa, Rafaelle Taynah Soares da Silva, Juan Eduardo Rios Rodriguez, Evandro Aulice de Peder Júnior   +8 more
doaj  

Clinicopathologic Characteristics and Treatment Outcomes of Penile Cancer [PDF]

The World Journal of Men's Health, 2017
Purpose: The aim of this study was to assess the clinicopathologic characteristics of penile cancer, including patterns of therapy, oncologic results, and survival.
Jong Kil Nam, Dong Hoon Lee, Sung Woo Park, Sung Chul Kam, Ki Soo Lee, Tae Hyo Kim, Taek Sang Kim, Cheol Kyu Oh, Hyun Jun Park, Tae Nam Kim   +9 more
doaj   +1 more source

High‐Efficiency Carriers’ Separation Strategy Based Ultrasmall‐Bandgap CuWO4 Sono‐Enhances GSH Antagonism for Cuproptosis Cascade Immunotherapy

Advanced Science, EarlyView.
This study prepares copper tungstate (CuWO4, CWO) nanoparticles for synergistic sono‐enhanced cuproptosis‐based cancer therapy. With an ultrasmall bandgap (1.71 eV), CWO facilitates efficient charge carrier separation under ultrasound, enhancing the generation of reactive oxygen species and the controlled release of Cu2+ ions cascade amplify oxidative ...
Lichao Zhu, Zhisheng Guo, Yu Luo, Haiyan Huang, Kexin Zhang, Bingbing Duan, Renmiao Peng, Haochen Yao, Chao Liang, Kaiyang Wang   +9 more
wiley   +1 more source

An Explainable Multimodal Artificial Intelligence Model Integrating Histopathological Microenvironment and EHR Phenotypes for Germline Genetic Testing in Breast Cancer

Advanced Science, EarlyView.
This study presents an explainable multimodal AI model, MAIGGT (Multimodal Artificial Intelligence Germline Genetic Testing), that combines whole‐slide histopathology with clinical data for accurate germline BRCA1/2 mutation prescreening. By integrating digital pathology and EHR phenotypes, MAIGCT enables cost‐effective, scalable hereditary breast ...
Zijian Yang, Changyuan Guo, Jiayi Li, Yalun Li, Lei Zhong, Pengming Pu, Tongxuan Shang, Lin Cong, Yongxin Zhou, Guangdong Qiao, Ziqi Jia, Hengyi Xu, Heng Cao, Yansong Huang, Tianyi Liu, Jian Liang, Jiang Wu, Dongxu Ma, Yuchen Liu, Ruijie Zhou, Xiang Wang, Jianming Ying, Meng Zhou, Jiaqi Liu   +23 more
wiley   +1 more source

Sebaceous carcinoma of the penis: As aggressive as it is rare

Urology Annals, 2019
Malignant neoplasm of the penis is a rare cancer in industrialized countries but is not uncommon in India. Nearly 95% of penile cancer is squamous cell carcinoma. Malignant neoplasms of the sebaceous glands, which are mostly confined to the head and neck
Ranil Johann Boaz, Chandan Phukan, S Mandeep, Antony Devasia   +3 more
doaj   +1 more source

Loss of STARD7 Triggers Metabolic Reprogramming and Cell Cycle Arrest in Breast Cancer

Advanced Science, EarlyView.
Breast cancer cells undergo metabolic and transcriptomic reprogramming to support aberrant cell proliferation. Their mitochondria rely on the transfer of phosphatidylcholine from the endoplasmic reticulum to their membranes by STARD7, a candidate upregulated in breast cancer, to be functional.
Ewelina Dondajewska, Paula Allepuz‐Fuster, Chloé Maurizy, Alexandre Hego, Sandra Ormenese, Quentin Lion, Arnaud Blomme, Pierre Close, Arnaud Lavergne, Latifa Karim, Marc Thiry, Ivan Nemazanyy, Roopesh Krishnankutty, Jair Marques Jr, Alex von Kriegsheim, Nathaniel F. Henneman, Ganna Panasyuk, Kateryna Shostak, Alain Chariot   +18 more
wiley   +1 more source

The Report of Two Cases of Metastasis to the Corpora Covernosa from Transitional Cell Carcinoma of the Bladder

پزشکی بالینی ابن سینا, 1999
Tow cases were studied and followed. Both of the cases were diagnosed    as   having    secondary   metastasis  of   penis  ( Primary  cancer  in  urinary    bladder).      Both  cases  were  operated  by  T.U.R  technique.  Both  patients returned   
Hooshang Bab-Al-Havaejee
doaj  

Anthocyanins Prevent Mastitis Exacerbation by Inhibiting PANoptosis Activation

Advanced Science, EarlyView.
PANoptosis activation is an effective therapeutic target during mastitis progression, and Gasdermin D activation is key factor contributing to blood milk barrier damage during mastitis, while cyanidin 3‐O‐galactoside can inhibit these targets to exert a protective effect. Therefore, the extraction of key active ingredients from plants for the treatment
Rui Feng, Lin Guo, Fan Wang, Qian Zhang, Guoyan Wang, Hefei Huang, Wei Du, Hong An, Yue Yang, Henghui Miao, Peng Zheng, Tingting Chu, Dengke Zhang, Xiaoxue Yan, Xiaoyu Mi, Qian Ma, Weilin Gao, Yushan Li, Song Li, Yong Zhang, Zhenliang Zhu, Yu Wang, Jun Liu, Xu Liu   +23 more
wiley   +1 more source

Cirugía de Mohs: Aplicación de la técnica a neoplasias del pene [PDF]

Actas Urológicas Españolas, 2007
La cirugía de Mohs es una técnica quirúrgica que permite la extirpación en capas de tumores cutáneos con los más elevados porcentajes de curación. Al mismo tiempo permite el máximo ahorro de tejido sano. Todo ello es posible gracias a la supervisión microscópica que posibilita analizar el 100% de los bordes tumorales de cada una de las capas y así ...
Cuevas, J., de Eusebio, E., Díez, E., Castiñeira, I.   +3 more
openaire   +4 more sources

CXCL13 Expression Promotes CAR T Cell Antitumor Activity and Potentiates Response to PD‐1 Blockade

Advanced Science, EarlyView.
This study demonstrates that engineering CAR T cells to express CXCL13 enhances their antitumor efficacy and significantly improves responsiveness to PD‐1 immune checkpoint blockade. CXCL13 promotes T cell persistence, and resistance to early exhaustion via the AKT‐mTOR pathway.
Yang Zhou, Wenli Zhao, Yihan Zhu, Hongyan Liu, Yicheng Sun, Zhengrong Gong, Xuanyi Li, Ziying Liu, Kang Wen, Yicheng Wang, Jie Ren, Ruipei Xiao, Ling Jiang, Yanfeng Hu, Enguang Bi, Xiaoyong Zhang   +15 more
wiley   +1 more source