Conquering the Synthesis and Functionalization of Bicyclo[1.1.1]pentanes. [PDF]
Shire BR, Anderson EA.
europepmc +1 more source
The Pharmacokinetics of Intravenous and Subcutaneous Ondansetron in Female Beagle Dogs
ABSTRACT The purpose of this study was to evaluate the pharmacokinetic profile of ondansetron following intravenous (IV) and subcutaneous (SC) administration in five healthy adult female Beagles. Dogs were administered ondansetron at 0.5 mg/kg IV and SC in a randomized crossover design.
Elena D. Landau +10 more
wiley +1 more source
Mechanism-Guided Development of Directed C-H Functionalization of Bicyclo[1.1.1]pentanes. [PDF]
Bunnell A +7 more
europepmc +1 more source
Predicting and Rationalizing Piezoelectricity in Racemic Bioorganic Molecular Crystals
Racemic molecular crystals, composed of equal mixtures of chiral enantiomeric components, are predicted to exhibit significant piezoelectric responses and favourable mechanical flexibility. This study identifies organic and bioorganic racemates as promising candidates for sustainable, lead‐free materials, enabling next‐generation applications in energy
Shubham Vishnoi, Sarah Guerin
wiley +2 more sources
Oxygen Attachment Dissociation of Protonated Reserpine and Its Analogs
ABSTRACT Rationale Carbon–carbon double bonds are ubiquitous structural motifs in natural products and pose a key challenge in locating their presence in analytes via MS‐based methods. Here, we use the alkaloid reserpine as a model system to examine whether OAD reactions can locate quaternary double bonds embedded in fused multicyclic structures ...
Jack G. Li +5 more
wiley +1 more source
Stereoselective Synthesis of Highly Functionalized Bicyclo[2.1.0]pentanes by Sequential [2 + 1] and [2 + 2] Cycloadditions. [PDF]
Keen B +5 more
europepmc +1 more source
In the presence of catalytic amounts of Pd nanoparticles generated from Pd2dba3/AgBF4, (E)‐β‐trimethylsilyl styrenes undergo with aryl iodides an exclusive Hiyama‐type C‐Si coupling pathway leading to trans‐stilbenes. Side arylation products are completely eliminated if performing the reaction in 1,3‐dimethyl‐2‐imidazolidinone (DMI), an environmentally
Nikolaos Koromilas +5 more
wiley +1 more source
Rapid Access to 3-Substituted Bicyclo[1.1.1]pentanes. [PDF]
Burton KI, MacMillan DWC.
europepmc +1 more source
Flavour Ester Synthesis by Immobilized Lipases: A Research Overview With Industrial Relevance
Research landscape of flavour ester synthesis by immobilized lipases, highlighting enzymatic routes, major research themes and aspects related to industrial relevance, including enzyme reuse, solvent‐free systems, process intensification and scale‐up potential.
Nicole Marasca +3 more
wiley +1 more source
Diastereoselective Cyclopropanation with Secondary Diazoacetamides to Access <i>endo</i>-Azabicyclo[3.1.0]hexane-6-carboxamides. [PDF]
Nguyen TH +4 more
europepmc +1 more source

