Results 141 to 150 of about 23,204,048 (210)

Oral and Inhaled Fosamprenavir Reverses Pepsin‐Induced Damage in a Laryngopharyngeal Reflux Mouse Model

The Laryngoscope, 2022
More than 20% of the US population suffers from laryngopharyngeal reflux. Although dietary/lifestyle modifications and alginates provide benefit to some, there is no gold standard medical therapy.
Nikki Johnston, Tina L Samuels, C. Goetz, L. Arnold, Brian C. Smith, Donna E. Seabloom, B. Wuertz, F. Ondrey, T. Wiedmann, N. Vuksanovic, N. Silvaggi, A. Mackinnon, James Miller, J. Bock, J. Blumin   +14 more
semanticscholar   +1 more source

Bovine pepsinogen and pepsin. IV. A new method of purification of the pepsin

Biochimica et Biophysica Acta (BBA) - Enzymology, 1971
A new purification procedure for bovine pepsin (EC 3.4.4.1) based on affinity chromatography, is more rapid, and gives a higher yield and activity than previous procedures. It may be used for purification of other pepsins and of pepsinogen. Pepsinogen is extracted from gastric mucosa, fractionated with ammonium sulfate, and activated to pepsin.
B, Nevaldine, B, Kassell
openaire   +2 more sources

The interaction of the green tea polyphenol (catechin) with pepsin: Insights from spectroscopic to molecular dynamics studies

Journal of Molecular Liquids, 2021
Pepsin is an aspartic proteinase that plays an essential role in controlling many biological processes, therapy, and pharmaceutical research. Catechins belong to the group of polyphenols that are the most basic chemical composition of green tea.
Elham Raeessi-Babaheydari, S. Farhadian, B. Shareghi   +2 more
semanticscholar   +1 more source

Pepsin as a Marker of Extraesophageal Reflux

Annals of Otology, Rhinology & Laryngology, 2010
Diagnosis of extraesophageal reflux (EER) currently relies on tools designed for diagnosis of gastroesophageal reflux. Such tools lack the sensitivity and reproducibility to detect the less frequent and mildly acidic reflux associated with upper airway disease. Pepsin has been posited to be a reliable biological marker of EER. Our aim was to present a
Tina L, Samuels, Nikki, Johnston
openaire   +2 more sources

A useful spectrophotometric rate assay for pepsin

Analytical Biochemistry, 1971
Abstract Phenyl sulfite is a specific substrate for pepsin, whose hydrolysis can be followed spectrophotometrically. This compound is superior to peptide substrates in its ease of synthesis and its ability to be monitered spectrophotometrically. The sulfite assay is therefore the method of choice for both routine and detailed assays of pepsin.
T P, Stein, T W, Reid, D, Fahrney
openaire   +2 more sources

Pepsin mediated synthesis of blue fluorescent copper nanoclusters for sensing of flutamide and chloramphenicol drugs

, 2021
Herein, we introduced a facile one-step green route for the synthesis of pepsin protected ultra-small blue fluorescent copper nanoclusters (pespsin-CuNCs) for the detection of flutamide and chloramphenicol drugs.
S. Borse, Z. Murthy, T. Park, S. K. Kailasa   +3 more
semanticscholar   +1 more source

Pepsin as a Marker for Pulmonary Aspiration

American Journal of Critical Care, 2002
• Background Although assessment for aspiration of small volumes of gastric contents in tube-fed patients receiving mechanical ventilation is important, available methods for this purpose are not wholly satisfactory. A potential method is immunoassay of tracheal secretions for the gastric enzyme pepsin.
Norma A, Metheny, Yie-Hwa, Chang, Jing Song, Ye, Sharon J, Edwards, Julie, Defer, Thomas E, Dahms, Barbara J, Stewart, Kathleen S, Stone, Ray E, Clouse   +8 more
openaire   +2 more sources

Digestion of food proteins: the role of pepsin

Critical reviews in food science and nutrition
The nutritive value of a protein is determined not only by its amino acid composition, but also by its digestibility in the gastrointestinal tract. The interaction between proteins and pepsin in the gastric stage is the first step and plays an important ...
Mengxiao Yang, Zhi Yang, David W. Everett, E. Gilbert, Harjinder Singh, A. Ye   +5 more
semanticscholar   +1 more source

Chicken Pepsin as a Rennet Substitute

Canadian Institute of Food Science and Technology Journal, 1984
Abstract Semi-purified chicken pepsin was prepared from proventriculae at a yield of 33% of the original pepsin activity using a procedure based on the method described by Bohak (1970) . Cheddar cheese was produced using the chicken pepsin preparation, and with calf rennet as a control, in two trials.
C.J. Findlay, D.W. Stanley, D.B. Emmons
openaire   +1 more source

Interaction behavior between five flavonoids and pepsin: Spectroscopic analysis and molecular docking

, 2021
Baicalin, myricetin, rutin, hesperidin and isoliquiritin are five classic flavonoids. Being both dietary and biologically active compounds, the accurate and full basic data for clarifying the binding mechanisms of the five flavonoids to pepsin remain ...
Jie Yu, Xiangrong Li, Hongyi Liu, Yanru Peng, Xuezhen Wang, Yongtao Xu   +5 more
semanticscholar   +1 more source