Analyzing pepsin degradation assay conditions used for allergenicity assessments to ensure that pepsin susceptible and pepsin resistant dietary proteins are distinguishable. [PDF]
PLoS ONE, 2017 The susceptibility of a dietary protein to proteolytic degradation by digestive enzymes, such as gastric pepsin, provides information on the likelihood of systemic exposure to a structurally intact and biologically active macromolecule, thus informing on
Rong Wang +8 more
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PLoS ONE, 2020 Pepsin plays an important role in laryngopharyngeal reflux (LPR), a risk factor for the development of hypopharyngeal squamous cell carcinomas (HPSCC). However, the role of pepsin in HPSCC is not clear.
Kai Niu +8 more
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The In Vitro Effect of Acidic-Pepsin on Nuclear Factor KappaB Activation and Its Related Oncogenic Effect on Normal Human Hypopharyngeal Cells. [PDF]
PLoS ONE, 2016 Extra-esophageal carcinogenesis has been widely discussed in relation to the chronic effects of laryngopharyngeal reflux and most prominently with pepsin historically central to this discussion.
Clarence T Sasaki +2 more
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Sensors, 2020 Salivary pepsin is a promising marker for the non-invasive diagnosis of laryngopharyngeal reflux (LPR). For reliable results regarding pepsin in saliva, it is critical to standardize the collection, storage, and pre-processing methods.
Young Ju Lee +5 more
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Variability and accuracy of multiple saliva pepsin measurements in laryngopharyngeal reflux patients
Journal of Otolaryngology - Head and Neck Surgery, 2023 Objective To study the variability and diagnostic value of multiple salivary pepsin measurements in the detection of laryngopharyngeal reflux (LPR).
Jerome R. Lechien, Francois Bobin
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Extra-Esophageal Pepsin from Stomach Refluxate Promoted Tonsil Hypertrophy. [PDF]
PLoS ONE, 2016 Gastroesophageal reflux is associated with numerous pathologic conditions of the upper aerodigestive tract. Gastric pepsin within reflux contributes to immunologic reactions in the tonsil.
Jin Hyun Kim +7 more
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Extraction and characterization of pepsin enzyme from the skipjack vicera (Katsuwonus pelamis) [PDF]
BIO Web of ConferencesPepsin is one of the digestive enzymes often used in various fields, especially for industry. Pepsin can be extracted from fish viceras. The aim of this research is to extract pepsin from the stomach of skipjack tuna, purify it, and to characterize ...
Muttaqin Roisul Adi Brilianto +6 more
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Effect of pH and protein composition on proteolysis of goat milk proteins by pepsin and pancreatin.
Food Research International, 2023 The roles of protein composition, pH and enzymes in goat milk protein hydrolysis is still unclear and the proteolysis of low abundant goat milk proteins has received limited attention.
K. Hettinga +5 more
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High Ionic Strength Enhances the Anti-Pepsin Activity of Titanium Dioxide Nanoparticles
Nano Biomedicine and Engineering, 2016 Gastro-esophageal reflux disease (GERD) is a state that evolves when there is a return of acid and pepsin enzyme into the esophagus. Inhibition of pepsin enzyme is one of the strategies used successfully for the treatment of GERD.
Hussein Kadhem Al-Hakeim +1 more
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Immobilization of Pepsin onto Chitosan Silica Nanobeads with Glutaraldehyde as Crosslink Agent
Bulletin of Chemical Reaction Engineering & Catalysis, 2014 Glutaraldehyde crosslinked chitosan - silica nanobeads have been used as a support in the immobiliza-tion process of pepsin. The effect of pH, pepsin concentration, and temperature on the characteristics of both free and immobilized pepsin had been ...
Sari Edi Cahyaningrum +1 more
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