Results 21 to 30 of about 23,204,048 (210)

Pepsin activity as a function of pH and digestion time on caseins and egg white proteins under static in vitro conditions.

Food & Function, 2021
The activity of pepsin, the gastric protease, is generally considered to be negligible for pH ≥ 4, based on the results obtained with a few purified globular proteins.
Lea Salelles, Juliane Floury, Steven Le Feunteun   +2 more
semanticscholar   +1 more source

Reduced Pepsin A Processing of Sonic Hedgehog in Parietal Cells Precedes Gastric Atrophy and Transformation*

Journal of Biological Chemistry, 2007
Sonic hedgehog (Shh) is not only essential to the development of the gastrointestinal tract, but is also necessary to maintain the characteristic acid-secreting phenotype of the adult stomach.
Y. Zavros, Meghna Waghray, Arthur Tessier, Longchuan Bai, A. Todisco, Deborah L Gumucio, L. Samuelson, A. Dlugosz, J. Merchant   +8 more
semanticscholar   +1 more source

Effects of acids, pepsin, bile acids, and trypsin on laryngopharyngeal reflux diseases: physiopathology and therapeutic targets

European Archives of Oto-Rhino-Laryngology, 2021
Laryngopharyngeal reflux disease (LPRD) is a general term for the reflux of gastroduodenal contents into the laryngopharynx, oropharynx and even the nasopharynx, causing a series of symptoms and signs.
Yading Li, Gaofan Xu, Bingduo Zhou, Yishuang Tang, Xiaowen Liu, Yue Wu, Yi Wang, J. Kong, Tingting Xu, Cong He, Shengliang Zhu, Xiaosu Wang, Jian-Na Zhang   +12 more
semanticscholar   +1 more source

Immunoserologic Pepsin Detection in The Saliva as a Non-Invasive Rapid Diagnostic Test for Laryngopharyngeal Reflux

Balkan Medical Journal, 2015
Background: The most common tool for the diagnosis of laryngopharyngeal reflux (LPR) is still 24-hours esophageal pH monitoring; there is lack of non-invasive, less expensive and accurate diagnostic tools for this frequent disease.
Emre Ocak, Gözde Kubat, İrfan Yorulmaz
doaj   +1 more source

THE ESTIMATION OF PEPSIN, TRYPSIN, PAPAIN, AND CATHEPSIN WITH HEMOGLOBIN

The Journal of General Physiology, 1938
In the hemoglobin method for the estimation of proteinase, denatured hemoglobin is digested under standard conditions, the undigested hemoglobin is precipitated with trichloracetic acid, and the amount of unprecipitated protein split products, which is a
M. L. Anson
semanticscholar   +1 more source

Interactions and effects of food additive dye Allura red on pepsin structure and protease activity; experimental and computational supports

Research in Pharmaceutical Sciences, 2021
Background and purpose: Today, color additives such as Allura red (AR) are widely used in different kinds of food products. Pepsin is a globular protein that is secreted as a digestive protease from the main cells in the stomach. Because of the important
Fatemeh Balaei, Mohabbat Ansari, Negin Farhadian, Sajad Moradi, Mohsen Shahlaei   +4 more
doaj   +1 more source

Label-Free Detection of Salivary Pepsin Using Gold Nanoparticle/Polypyrrole Nanocoral Modified Screen-Printed Electrode

Sensors, 2018
Detection of salivary pepsin has been given attention as a new diagnostic tool for laryngopharyngeal reflux (LPR) disease, because saliva collection is non-invasive and relatively comfortable.
Doyeon Lee, Young Ju Lee, Young-Gyu Eun, Gi-Ja Lee   +3 more
doaj   +1 more source

Laryngopharyngeal Reflux: Symptoms, Signs, and Presence of Pepsin in Saliva - A Reliable Diagnostic Triad

International Archives of Otorhinolaryngology, 2021
Introduction Twenty-four-hour multichannel intraluminal impedance with double probe pH monitoring (MII-pH), though considered the most sensitive tool for the diagnosis of gastroesophageal reflux disease (GERD), is invasive, time consuming, not widely ...
Shilpa Divakaran, Sivaa Rajendran, Roshan Marie Thomas, Jaise Jacob, Mary Kurien   +4 more
doaj   +1 more source

Diagnostic utility of salivary pepsin in laryngopharyngeal reflux: a systematic review and meta-analysis

Brazilian Journal of Otorhinolaryngology, 2023
Objectives: Salivary pepsin has emerged as a biomarker for Laryngopharyngeal Reflux (LPR), which, however, has been questioned for its efficacy due to a lack of supporting medical data.
Wuyang Jing, Wenlong Luo, Lan Lou
doaj   +1 more source

Pepsin promotes IL-8 signaling-induced epithelial–mesenchymal transition in laryngeal carcinoma

Cancer Cell International, 2019
Background Laryngopharyngeal reflux (LPR), with its increasing morbidity, is attracting considerable attention. In recent years, the causal role between LPR and laryngeal carcinoma has been debated.
Jia-Jie Tan, Lu Wang, Ting-Ting Mo, Jie Wang, Mei-Gui Wang, Xiang-Ping Li   +5 more
doaj   +1 more source