Results 61 to 70 of about 23,204,048 (210)

Presence of small resistant peptides from new in vitro digestion assays detected by liquid chromatography tandem mass spectrometry: An implication of allergenicity prediction of novel proteins?

PLoS ONE, 2020
The susceptibility of newly expressed proteins to digestion by gastrointestinal proteases (e.g., pepsin) has long been regarded as one of the important endpoints in the weight-of-evidence (WOE) approach to assess the allergenic risk of genetically ...
Rong Wang, Yanfei Wang, Thomas C Edrington, Zhenjiu Liu, Thomas C Lee, Andre Silvanovich, Hong S Moon, Zi L Liu, Bin Li   +8 more
doaj   +1 more source

A Spectrophotometric Investigation of the Pepsinogen-Pepsin Conversion

Journal of Biological Chemistry, 1972
Abstract A spectrophotometric assay of the conversion of pepsinogen into pepsin is described. This assay allows accurate investigations at early stages in the reaction which demonstrate that the conversion is more complex than a simple autocatalytic process and that a unimolecular self activation may also be involved.
openaire   +2 more sources

Detection of pepsin and IL-8 in saliva of adult asthmatic patients

Journal of Asthma and Allergy, 2019
Samuel Marshall,1 Alec J McCann,1 Tina L Samuels,1 Amy Blair,2 Valerie Bonne,2 Nikki Johnston,1,3 Jamie Koufman41Department of Otolaryngology and Communication Sciences, Medical College of Wisconsin, Milwaukee, WI, USA; 2Department of Medicine, Medical ...
Marshall S, McCann AJ, Samuels TL, Blair A, Bonne V, Johnston N, Koufman J   +6 more
doaj  

Pathogenesis of pepsin-induced gastroesophageal reflux disease with advanced diagnostic tools and therapeutic implications

Frontiers in Medicine
Gastroesophageal reflux disease (GERD) is a common gastrointestinal disorder that significantly affects populations in both developing and developed countries.
Chong Li, Xiwen Cao, Hongxia Wang
doaj   +1 more source

Comparison of Three Methods Used in the Diagnosis of Extraesophageal Reflux in Children with Chronic Otitis Media with Effusion

Gastroenterology Research and Practice, 2015
Objectives. Detection of extraesophageal reflux (EER) in children with chronic otitis media with effusion (OME) using three different diagnostic methods. Methods.
Martin Formánek, Pavel Komínek, Petr Matoušek, Radoslava Tomanova, Ondřej Urban, Karol Zeleník   +5 more
doaj   +1 more source

Diagnostic value of fasting hypopharyngeal salivary pepsin concentration test for laryngopharyngeal reflux disease

World Journal of Otorhinolaryngology-Head and Neck Surgery
Objective To investigate the diagnostic value of the fasting hypopharyngeal salivary pepsin concentration test for laryngopharyngeal reflux disease (LPRD).
Chao‐Feng Liu, Chen‐Jie Hou, Ting Chen, Liu‐Qing Chen, Jing‐Yi Zheng, Yu‐Jin Zheng, Xiao‐Wei Zheng   +6 more
doaj   +1 more source

Clinical Studies on a New Pepsin Inhibitor.

Experimental Biology and Medicine, 1943
SummaryCalcium carbonate and an aluminum hydroxide preparation caused inhibition of peptic activity and a rise in pH of the gastric juice of peptic ulcer patients. One hundred mg of sodium lauryl sulfate caused no significant changes, whereas 200 mg caused a slight rise in pH and decrease in peptic activity.
F. Steigmann, A. R. Marks
openaire   +1 more source

Effects of trypsin and pepsin detection on chronic otitis media with effusion

Heliyon
Chronic otitis media with effusion (COME) is a common cause of hearing loss in children and adults. Laryngopharyngeal reflux (LPR) is often overlooked in the clinical management of COME complicated by LPR. This study aimed to investigate the presence and
Zeqi Zhao, Zhengzhong Han, Yudi Shao, Tingting Tang, Caiji Wang, Bing Xu, Zhenlu Zhao, Xi Shi, Dan Jin, Wei Li   +9 more
doaj   +1 more source

Transformation of Peptides into Non-Peptides. Synthesis of Computer-Generated Enzyme Inhibitors

CHIMIA, 1997
With the intent of discovering novel molecular scaffolds for designing protease inhibitors, the computer program GrowMol was used to generate peptidemimetic inhibitors of aspartic proteases.
Daniel H. Richu, Regine S. Bohacek, Natalie A. Dales, Peter Glunz, Amy S. Ripka   +4 more
doaj   +2 more sources

Extraction, purification and characterization of fish pepsin: a critical review.

, 2011
Zhao Lisha, S. Budge, A. Ghaly, M. Brooks, D. Dave   +4 more
semanticscholar   +1 more source