Results 1 to 10 of about 24,885 (117)

Genomic Insights into the Distribution of Peptidases and Proteolytic Capacity among Prevotella and Paraprevotella Species.

open access: yesMicrobiology Spectrum, 2022
Bacterial peptidases play important roles in health and nutrient digestion in both humans and animals, especially ruminant animals. In this study, we examined and compared the various peptidases (both total and secretory) among species of Prevotella (44 ...
Zhongtang Yu, Amlan Kumar Patra
exaly   +3 more sources

The protease code of the bacterial gut microbiota: ecological regulation, barrier disruption, and rewiring host defense and signaling [PDF]

open access: yesGut Microbes
The human gastrointestinal tract is home to a dense and diverse microbial ecosystem that functions as a complex superorganism. Yet, the enzymatic machinery responsible for orchestrating this coexistence remains underexplored.
Ulrich Eckhard   +3 more
doaj   +2 more sources

An Essential Signal Peptide Peptidase Identified in an RNAi Screen of Serine Peptidases of Trypanosoma brucei

open access: yesPLoS ONE, 2015
The serine peptidases of Trypanosoma brucei have been viewed as potential drug targets. In particular, the S9 prolyl oligopeptidase subfamily is thought to be a good avenue for drug discovery.
Jeremy C. Mottram   +2 more
exaly   +2 more sources

Peptidase Regulation in Trichophyton rubrum Is Mediated by the Synergism Between Alternative Splicing and StuA-Dependent Transcriptional Mechanisms

open access: yesFrontiers in Microbiology, 2022
Trichophyton rubrum is the most common causative agent of dermatophytosis worldwide and uses keratinized substrates such as skin and nails as its main source of nutrition during infection.
Leonardo Martins-Santana   +4 more
doaj   +1 more source

Taxon-Specific Shifts in Bacterial and Archaeal Transcription of Dissolved Organic Matter Cycling Genes in a Stratified Fjord

open access: yesmSystems, 2021
A considerable fraction of organic matter derived from photosynthesis in the euphotic zone settles into the ocean’s interior and, as it progresses, is degraded by diverse microbial consortia that utilize a suite of extracellular enzymes and membrane ...
Benjamin Pontiller   +6 more
doaj   +1 more source

The identification of two M20B family peptidases required for full virulence in Staphylococcus aureus

open access: yesFrontiers in Cellular and Infection Microbiology, 2023
We have previously demonstrated that deletion of an intracellular leucine aminopeptidase results in attenuated virulence of S. aureus. Herein we explore the role of 10 other aminopeptidases in S. aureus pathogenesis. Using a human blood survival assay we
Nathanial J. Torres   +7 more
doaj   +1 more source

Peptidomics as a Tool to Assess the Cleavage of Wine Haze Proteins by Peptidases from Drosophila suzukii Larvae

open access: yesBiomolecules, 2023
Thermolabile grape berry proteins such as thaumatin-like proteins (TLPs) and chitinases (CHIs) promote haze formation in bottled wines if not properly fined.
Wendell Albuquerque   +10 more
doaj   +1 more source

In Silico Predictions of Ecological Plasticity Mediated by Protein Family Expansions in Early-Diverging Fungi

open access: yesJournal of Fungi, 2022
Early-diverging fungi (EDF) are ubiquitous and versatile. Their diversity is reflected in their genome sizes and complexity. For instance, multiple protein families have been reported to expand or disappear either in particular genomes or even whole ...
Małgorzata Orłowska, Anna Muszewska
doaj   +1 more source

Proteomic Studies to Understand the Mechanisms of Peach Tissue Degradation by Monilinia laxa

open access: yesFrontiers in Plant Science, 2020
Monilinia laxa is a necrotrophic plant pathogen able to infect and produce substantial losses on stone fruit. Three different isolates of M. laxa were characterized according to their aggressiveness on nectarines. M.
Silvia Rodríguez-Pires   +3 more
doaj   +1 more source

Lysosomal peptidases—intriguing roles in cancer progression and neurodegeneration

open access: yesFEBS Open Bio, 2022
Lysosomal peptidases are hydrolytic enzymes capable of digesting waste proteins that are targeted to lysosomes via endocytosis and autophagy. Besides intracellular protein catabolism, they play more specific roles in several other cellular processes and ...
Janko Kos   +3 more
doaj   +1 more source

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