Results 21 to 30 of about 31,169 (289)
Natural, engineered and synthetic inhibitors of kallikrein-related peptidases [PDF]
, 2012 There is a rapidly growing appreciation of the important physiological roles played by kallikreins and kallikrein-related peptidases (KLKs). Recent studies have revealed that these enzymes control key events in processes as diverse as inflammation and ...
Joakim E. Swedberg +5 more
core +1 more source
Immunoproteomics of peptidases from Lactobacillus helveticus
, 2009 Milk proteins beyond their high nutritional quality are a source of peptides with biological activity. These bioactive peptides would exert different activities in vivo, affecting the cardiovascular, endocrine, immune, digestive or nervous systems.
Mollé, Daniel +7 more
core +5 more sources
New families of carboxyl peptidases: serine-carboxyl peptidases and glutamic peptidases [PDF]
Journal of Biochemistry, 2011 Peptidases or proteinases are now classified into seven families based on the nature of the catalytic residues [MEROPS-the peptidase database (http://merops.sanger.ac.uk/)]. They are aspartic- (first described in 1993), cysteine- (1993), serine- (1993) metallo- (1993), threonine- (1997), glutamic- (2004) and asparagine-peptidase (2010).
openaire +2 more sources
Peptidases: promising antifungal targets of the human fungal pathogen, Cryptococcus neoformans
FACETS, 2022 Cryptococcus neoformans is a globally important fungal pathogen, primarily inflicting disease on immunocompromised individuals. The widespread use of antifungal agents in medicine and agriculture supports the development of antifungal resistance through ...
Davier Gutierrez-Gongora +1 more
doaj +1 more source
Frontiers in Pharmacology, 2022 A prodrug approach is a powerful method to temporarily change the physicochemical and thus, pharmacokinetic properties of drugs. However, in site-selective targeted prodrug delivery, tissue or cell-specific bioconverting enzyme is needed to be utilized ...
Agathe Hugele +6 more
doaj +1 more source
Frontiers in Bioengineering and Biotechnology, 2020 Basidiomycetes populate a wide range of ecological niches but unlike ascomycetes, their capabilities to decay plant polymers and their potential for biotechnological approaches receive less attention. Particularly, identification and isolation of CAZymes
Habibu Aliyu +5 more
doaj +1 more source
Pathogens, 2023 Babesia bovis and Theileria annulata are tick-borne hemoprotozoans that impact bovine health and are responsible for considerable fatalities in tropical and subtropical regions around the world. Both pathogens infect the same vertebrate host, are closely
Tomás Javier Poklepovich +4 more
doaj +1 more source
Biochimie, 2019 The distribution of all peptidase homologues across all phyla of organisms was analysed to determine within which kingdom each of the 271 families originated. No family was found to be ubiquitous and even peptidases thought to be essential for life, such as signal peptidase and methionyl aminopeptides are missing from some clades.
Neil D. Rawlings, Alex Bateman
openaire +2 more sources
Pharmaceutics, 2021 To date, there is no effective treatment for celiac disease (CD, gluten enteropathy), an autoimmune disease caused by gluten-containing food. Celiac patients are supported by a strict gluten-free diet (GFD).
Yakov E. Dunaevsky +5 more
doaj +1 more source
In Silico Survey and Characterization of Babesia microti Functional and Non-Functional Proteases
Pathogens, 2021 Human babesiosis caused by the intraerythrocytic apicomplexan Babesia microti is an expanding tick-borne zoonotic disease that may cause severe symptoms and death in elderly or immunocompromised individuals.
Monica Florin-Christensen +3 more
doaj +1 more source