Results 11 to 20 of about 2,831,907 (343)

Marine Invertebrate Peptides: Antimicrobial Peptides [PDF]

open access: yesFrontiers in Microbiology, 2021
Antimicrobial peptides are an important component of many organisms’ innate immune system, with a good inhibitory or killing effect against the invading pathogens. As a type of biological polypeptide with natural immune activities, antimicrobial peptides have a broad spectrum of antibacterial, antiviral, and antitumor activities.
Ran Wu   +9 more
openaire   +3 more sources

Peptides, Antibodies, Peptide Antibodies and More [PDF]

open access: yesInternational Journal of Molecular Sciences, 2019
The applications of peptides and antibodies to multiple targets have emerged as powerful tools in research, diagnostics, vaccine development, and therapeutics. Antibodies are unique since they, in theory, can be directed to any desired target, which illustrates their versatile nature and broad spectrum of use as illustrated by numerous applications of ...
Nicole Trier, Paul Hansen, Gunnar Houen
openaire   +4 more sources

Accurate control of dual-receptor-engineered T cell activity through a bifunctional anti-angiogenic peptide

open access: yesJournal of Hematology & Oncology, 2018
Background Chimeric antigen receptors (CARs) presented on T cell surfaces enable redirection of T cell specificity, which has enormous promise in antitumor therapy.
Erhao Zhang   +11 more
doaj   +1 more source

Quantifying systemic molecular networks affected during high altitude de-acclimatization

open access: yesScientific Reports, 2023
High altitude acclimatization and disease have been the centerpiece of investigations concerning human health at high altitude. Almost all investigations have focused on either understanding and ameliorating high altitude disease or finding better ...
Subhojit Paul   +5 more
doaj   +1 more source

Label-free method for anti-glucopeptide antibody detection in Multiple Sclerosis

open access: yesMethodsX, 2015
Surface plasmon resonance technique is particularly interesting in immunology because it has the potential to visualize label-free antigen-antibody interactions in real-time, thus enabling antibody detection and monitoring.
Feliciana Real-Fernández   +4 more
doaj   +1 more source

CD146 Associates with Gp130 to Control a Macrophage Pro‐inflammatory Program That Regulates the Metabolic Response to Obesity

open access: yesAdvanced Science, 2022
The mechanism of obesity‐related metabolic dysfunction involves the development of systemic inflammation, largely mediated by macrophages. Switching of M1‐like adipose tissue macrophages (ATMs) to M2‐like ATMs, a population of macrophages associated with
Hongxia Duan   +10 more
doaj   +1 more source

C-peptide: a predictor of cardiovascular mortality in subjects with established atherosclerotic disease [PDF]

open access: yes, 2017
Aim: Insulin resistance and type 2 diabetes are independent risk factors for cardiovascular diseases. Levels of C-peptide are increased in these patients and its role in the atherosclerosis progression was studied in vitro and in vivo over the past ...
Ballanti, Marta   +13 more
core   +1 more source

Bioactive Peptides [PDF]

open access: yesJournal of AOAC INTERNATIONAL, 2008
Abstract Peptides with biological activities, released during gastrointestinal digestion or food processing, play an important role in metabolic regulation and modulation, suggesting their potential use as nutraceuticals and functional food ingredients for health promotion and disease risk reduction.
Fereidoon, Shahidi, Ying, Zhong
openaire   +2 more sources

Regulated Inositol‐Requiring Protein 1‐Dependent Decay as a Mechanism of Corin RNA and Protein Deficiency in Advanced Human Systolic Heart Failure [PDF]

open access: yes, 2014
BACKGROUND: The compensatory actions of the endogenous natriuretic peptide system require adequate processing of natriuretic peptide pro‐hormones into biologically active, carboxyl‐terminal fragments.
Barton, P   +5 more
core   +1 more source

Recombination of a dual-CAR-modified T lymphocyte to accurately eliminate pancreatic malignancy

open access: yesJournal of Hematology & Oncology, 2018
Background The therapeutic application of T cells endowing with chimeric antigen receptors (CARs) is faced with “on-target, off-tumor” toxicity against solid tumors, particularly in the treatment of the pancreatic cancer.
Erhao Zhang   +12 more
doaj   +1 more source

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