Results 11 to 20 of about 2,268,571 (366)
Arginine-rich peptides destabilize the plasma membrane, consistent with a pore formation translocation mechanism of cell penetrating peptides [PDF]
Biophysical Journal, Volume 97, Issue 7, 7 October 2009, Pages
1917-1925, 2009 Recent molecular dynamics simulations (Herce and Garcia, PNAS, 104: 20805 (2007)) have suggested that the arginine-rich HIV Tat peptides might be able to translocate by destabilizing and inducing transient pores in phospholipid bilayers.
Enrique, N. +7 more
core +4 more sources
Marine Invertebrate Peptides: Antimicrobial Peptides [PDF]
Frontiers in Microbiology, 2021 Antimicrobial peptides are an important component of many organisms’ innate immune system, with a good inhibitory or killing effect against the invading pathogens. As a type of biological polypeptide with natural immune activities, antimicrobial peptides have a broad spectrum of antibacterial, antiviral, and antitumor activities.
Ran Wu +9 more
openaire +3 more sources
Identifying sequential residue patterns in bitter and umami peptides [PDF]
ACS Food Sci. Technol. 2022, 2, 11, 1773--1780, 2022 The primary structures of peptides, originating from food proteins, affect their taste. Connecting primary structure to taste, however, is difficult because the size of the peptide sequence space increases exponentially with increasing peptide length, while experimentally-labeled data on peptides' tastes remain scarce.
arxiv +1 more source
C-peptide is a bioactive peptide [PDF]
Diabetologia, 2007 -ATPase.Nerveconductionvelocity.RedbloodcelldeformabilityAbbreviationsBB/Wor BioBreeding/WorcestereNOS endothelial nitric oxide synthaseICAM-1 intracellular adhesion molecule 1MAPK mitogen-activated protein kinaseNCV nerve conduction velocityDuring the past decade, reports from several laboratorieshave focused on the physiological effects of C-peptide ...
John Wahren, Hans Jörnvall, K. Ekberg
openaire +3 more sources
, 2021 Peptides produced by hydrolysis of milk proteins during technological processes and storage greatly influence the functional and biological properties of dairy products. This chapter deals with the main analytical techniques for milk peptide analysis.
Recio, Isidra +3 more
openaire +2 more sources
Journal of Hematology & Oncology, 2018 Background Chimeric antigen receptors (CARs) presented on T cell surfaces enable redirection of T cell specificity, which has enormous promise in antitumor therapy.
Erhao Zhang +11 more
doaj +1 more source
Evaluation of a PACAP Peptide Analogue Labeled with (68)Ga Using Two Different Chelating Agents. [PDF]
, 2016 OBJECTIVE: The authors have conjugated chelating agents (DOTA and NODAGA) with a peptide (pituitary adenylate cyclase-activating peptide [PACAP] analogue) that has a high affinity for VPAC1 receptors expressed on cancer cells.
Chen, Chang-Po +6 more
core +2 more sources
Peptides, Antibodies, Peptide Antibodies and More [PDF]
International Journal of Molecular Sciences, 2019 The applications of peptides and antibodies to multiple targets have emerged as powerful tools in research, diagnostics, vaccine development, and therapeutics. Antibodies are unique since they, in theory, can be directed to any desired target, which illustrates their versatile nature and broad spectrum of use as illustrated by numerous applications of ...
Nicole Trier, Paul Hansen, Gunnar Houen
openaire +5 more sources
Peptide Stapling Applied to Antimicrobial Peptides
Antibiotics, 2023 Antimicrobial peptides (AMPs) are considered a promising therapeutic approach against multi-drug resistant microorganisms. Besides their advantages, there are limitations to be overcome so that these molecules can become market competitive. One of the biggest limitations is proteolytic susceptibility, which could be overcome by structural modifications
Ana Laura Pereira Lourenço +4 more
openaire +3 more sources
Introduction of d-Glutamate at a Critical Residue of Aβ42 Stabilizes a Prefibrillary Aggregate with Enhanced Toxicity. [PDF]
, 2016 The amyloid beta peptide 42 (Aβ42) is an aggregation-prone peptide that plays a pivotal role in Alzheimer's disease. We report that a subtle perturbation to the peptide through a single chirality change at glutamate 22 leads to a pronounced delay in the ...
Dutta, Subrata +3 more
core +1 more source