Results 11 to 20 of about 3,746,064 (390)

Marine Invertebrate Peptides: Antimicrobial Peptides [PDF]

open access: yesFrontiers in Microbiology, 2021
Antimicrobial peptides are an important component of many organisms’ innate immune system, with a good inhibitory or killing effect against the invading pathogens. As a type of biological polypeptide with natural immune activities, antimicrobial peptides have a broad spectrum of antibacterial, antiviral, and antitumor activities.
Ran Wu   +9 more
openaire   +3 more sources

Peptides, Antibodies, Peptide Antibodies and More [PDF]

open access: yesInternational Journal of Molecular Sciences, 2019
The applications of peptides and antibodies to multiple targets have emerged as powerful tools in research, diagnostics, vaccine development, and therapeutics. Antibodies are unique since they, in theory, can be directed to any desired target, which illustrates their versatile nature and broad spectrum of use as illustrated by numerous applications of ...
Nicole Trier, Paul Hansen, Gunnar Houen
openaire   +4 more sources

Accurate Proteome-wide Label-free Quantification by Delayed Normalization and Maximal Peptide Ratio Extraction, Termed MaxLFQ *

open access: yesMolecular & Cellular Proteomics, 2014
Protein quantification without isotopic labels has been a long-standing interest in the proteomics field. However, accurate and robust proteome-wide quantification with label-free approaches remains a challenge. We developed a new intensity determination
J. Cox   +5 more
semanticscholar   +1 more source

Cholesterol-directed nanoparticle assemblies based on single amino acid peptide mutations activate cellular uptake and decrease tumor volume. [PDF]

open access: yes, 2017
Peptide drugs have been difficult to translate into effective therapies due to their low in vivo stability. Here, we report a strategy to develop peptide-based therapeutic nanoparticles by screening a peptide library differing by single-site amino acid ...
Landry, Markita P   +4 more
core   +1 more source

CD146 Associates with Gp130 to Control a Macrophage Pro‐inflammatory Program That Regulates the Metabolic Response to Obesity

open access: yesAdvanced Science, 2022
The mechanism of obesity‐related metabolic dysfunction involves the development of systemic inflammation, largely mediated by macrophages. Switching of M1‐like adipose tissue macrophages (ATMs) to M2‐like ATMs, a population of macrophages associated with
Hongxia Duan   +10 more
doaj   +1 more source

Antisense PNA accumulates in Escherichia coli and mediates a long post-antibiotic effect [PDF]

open access: yes, 2007
Antisense agents that target growth-essential genes display surprisingly potent bactericidal properties. In particular, peptide nucleic acid (PNA) and phosphorodiamidate morpholino oligomers linked to cationic carrier peptides are effective in time kill ...
Behmanesh, Mehrdad   +9 more
core   +2 more sources

Label-free method for anti-glucopeptide antibody detection in Multiple Sclerosis

open access: yesMethodsX, 2015
Surface plasmon resonance technique is particularly interesting in immunology because it has the potential to visualize label-free antigen-antibody interactions in real-time, thus enabling antibody detection and monitoring.
Feliciana Real-Fernández   +4 more
doaj   +1 more source

Catalytically active peptide–gold nanoparticle conjugates: Prospecting for artificial enzymes [PDF]

open access: yes, 2020
The self‐assembly of peptides onto the surface of gold nanoparticles has emerged as a promising strategy towards the creation of artificial enzymes.
Berger, Allison A.   +2 more
core   +1 more source

Effects of growth factors and receptor blockade on gastrointestinal cancer [PDF]

open access: yes, 2004
The advent of recombinant peptide technology offers the potential to use one or several peptides to treat a variety of gastrointestinal conditions. However, although cell culture and animal models have shown proof of concept, we are still at a relatively
Ghosh, S, Playford, RJ, Wassan, H
core   +2 more sources

Bioactive Peptides [PDF]

open access: yesJournal of AOAC INTERNATIONAL, 2008
Abstract Peptides with biological activities, released during gastrointestinal digestion or food processing, play an important role in metabolic regulation and modulation, suggesting their potential use as nutraceuticals and functional food ingredients for health promotion and disease risk reduction.
Fereidoon, Shahidi, Ying, Zhong
openaire   +2 more sources

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