Immunotherapy with peptides [PDF]
Specific allergen immunotherapy is clinically effective and disease modifying. It has a duration of effect that exceeds the treatment period and prevents both the progression of allergic rhinitis to asthma and the acquisition of new allergic sensitizations.
Daniel M. Moldaver, Mark Larché
openaire +3 more sources
A phage-displayed peptide recognizing porcine aminopeptidase N is a potent small molecule inhibitor of PEDV entry [PDF]
Three phage-displayed peptides designated H, S and F that recognize porcine aminopeptidase N (pAPN), the cellular receptor of porcine transmissible gastroenteritis virus (TGEV) were able to inhibit cell infection by TGEV.
Cong, Yingying+6 more
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Dimensionality of Carbon Nanomaterials Determines the Binding and Dynamics of Amyloidogenic Peptides: Multiscale Theoretical Simulations [PDF]
Experimental studies have demonstrated that nanoparticles can affect the rate of protein self-assembly, possibly interfering with the development of protein misfolding diseases such as Alzheimer's, Parkinson's and prion disease caused by aggregation and ...
A Albanese+88 more
core +7 more sources
Self-assembly of bioactive peptides, peptide conjugates, and peptide mimetic materials [PDF]
Self-assembling peptide and peptide conjugates have attracted great attention due to their biocompatibility, biodegradability and biofunctionality. This review covers self-assembly of amphiphilic peptides and peptide mimetic materials, as well as their potential applications.
Charlotte J. C. Edwards-Gayle+1 more
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Background Radiotherapy is widely applied in breast cancer treatment, while radiotherapy resistance is inevitable. TGF-β1 has been considered to be an endogenous factor for the development of radiotherapy resistance.
Fayun Zhang+7 more
doaj +1 more source
Pancreatic cancer-derived S-100A8 N-terminal peptide: a diabetes cause? [PDF]
BACKGROUND: Our aim was to identify the pancreatic cancer diabetogenic peptide. METHODS: Pancreatic tumor samples from patients with (n=15) or without (n=7) diabetes were compared with 6 non-neoplastic pancreas samples using SDS-PAGE.
BALDO G+12 more
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Peptide exchange on MHC-I by TAPBPR is driven by a negative allostery release cycle. [PDF]
Chaperones TAPBPR and tapasin associate with class I major histocompatibility complexes (MHC-I) to promote optimization (editing) of peptide cargo. Here, we use solution NMR to investigate the mechanism of peptide exchange.
A Bailey+62 more
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Crystal structure of methyl 1-(2-(fluorosulfonyl)ethyl)-2-oxocyclopentanecarboxylate, C9H13FO5S
C9H13FO5S, triclinic, P1̅ (no. 2), a = 5.9390(3) Å, b = 8.1581(4) Å, c = 11.3823(8) Å, α = 89.498(3)°, β = 85.314(5)°, γ = 84.916(5)°, V = 547.48(5) Å3, Z = 2, Rgt(F) = 0.0303, wRref(F2) = 0.0811, T = 293 K.
Govender Kimberleigh B.+4 more
doaj +1 more source
Effects of a synthetic bioactive peptide on neurite growth and nerve growth factor release in chondroitin sulfate hydrogels. [PDF]
Previous work has revealed robust dorsal root ganglia neurite growth in hydrogels of chondroitin sulfate. In the current work, it was determined whether addition of a synthetic bioactive peptide could augment neurite growth in these matrices via enhanced
Beier, Brooke L+3 more
core +1 more source
Crystal structure of (E)-2-(4-cyanophenyl)ethenesulfonyl fluoride, C9H6FNO2S
C9H6FNO2S, triclinic, P1̄ (no. 2), a = 7.2786(2) Å, b = 8.1014(3) Å, c = 16.1084(5) Å, α = 76.320(1)°, β = 87.918(1)°, γ = 80.784(1)°, V = 911.00(5) Å3, Z = 4, Rgt(F) = 0.0298, wRref(F2) = 0.0857, T = 100(2) K.
Brasil Edikarlos+4 more
doaj +1 more source