Results 31 to 40 of about 3,466,843 (390)

APD3: the antimicrobial peptide database as a tool for research and education

open access: yesNucleic Acids Res., 2015
The antimicrobial peptide database (APD, http://aps.unmc.edu/AP/) is an original database initially online in 2003. The APD2 (2009 version) has been regularly updated and further expanded into the APD3.
Guangshun Wang, Xia Li, Zhe Wang
semanticscholar   +1 more source

Regulated Inositol‐Requiring Protein 1‐Dependent Decay as a Mechanism of Corin RNA and Protein Deficiency in Advanced Human Systolic Heart Failure [PDF]

open access: yes, 2014
BACKGROUND: The compensatory actions of the endogenous natriuretic peptide system require adequate processing of natriuretic peptide pro‐hormones into biologically active, carboxyl‐terminal fragments.
Barton, P   +5 more
core   +1 more source

Crystal structure of methyl 1-(2-(fluorosulfonyl)ethyl)-2-oxocyclopentanecarboxylate, C9H13FO5S

open access: yesZeitschrift für Kristallographie - New Crystal Structures, 2017
C9H13FO5S, triclinic, P1̅ (no. 2), a = 5.9390(3) Å, b = 8.1581(4) Å, c = 11.3823(8) Å, α = 89.498(3)°, β = 85.314(5)°, γ = 84.916(5)°, V = 547.48(5) Å3, Z = 2, Rgt(F) = 0.0303, wRref(F2) = 0.0811, T = 293 K.
Govender Kimberleigh B.   +4 more
doaj   +1 more source

PKC-ζ mediated reduction of the extracellular vesicles-associated TGF-β1 overcomes radiotherapy resistance in breast cancer

open access: yesBreast Cancer Research, 2023
Background Radiotherapy is widely applied in breast cancer treatment, while radiotherapy resistance is inevitable. TGF-β1 has been considered to be an endogenous factor for the development of radiotherapy resistance.
Fayun Zhang   +7 more
doaj   +1 more source

The IkB kinase inhibitor nuclear factor-kB essential modulator–binding domain peptide for inhibition of balloon injury-induced neointimal formation [PDF]

open access: yes, 2009
Objective—The activation of nuclear factor-kB (NF-kB) is a crucial step in the arterial wall’s response to injury. The identification and characterization of the NF-kB essential modulator– binding domain (NBD) peptide, which can block the activation of
Carnuccio, R.   +12 more
core   +1 more source

Self-assembly of bioactive peptides, peptide conjugates, and peptide mimetic materials [PDF]

open access: yesOrganic & Biomolecular Chemistry, 2017
Self-assembling peptide and peptide conjugates have attracted great attention due to their biocompatibility, biodegradability and biofunctionality. This review covers self-assembly of amphiphilic peptides and peptide mimetic materials, as well as their potential applications.
Charlotte J. C. Edwards-Gayle   +1 more
openaire   +3 more sources

Crystal structure of (E)-2-(4-cyanophenyl)ethenesulfonyl fluoride, C9H6FNO2S

open access: yesZeitschrift für Kristallographie - New Crystal Structures, 2019
C9H6FNO2S, triclinic, P1̄ (no. 2), a = 7.2786(2) Å, b = 8.1014(3) Å, c = 16.1084(5) Å, α = 76.320(1)°, β = 87.918(1)°, γ = 80.784(1)°, V = 911.00(5) Å3, Z = 4, Rgt(F) = 0.0298, wRref(F2) = 0.0857, T = 100(2) K.
Brasil Edikarlos   +4 more
doaj   +1 more source

Discovery and characterization of prolactin neutralizing monoclonal antibodies for the treatment of female-prevalent pain disorders

open access: yesmAbs, 2023
Prolactin (PRL) has recently been demonstrated to elicit female-selective nociceptor sensitization and increase pain-like behaviors in female animals.
Stephanie Maciuba   +13 more
doaj   +1 more source

Antisense PNA accumulates in Escherichia coli and mediates a long post-antibiotic effect [PDF]

open access: yes, 2007
Antisense agents that target growth-essential genes display surprisingly potent bactericidal properties. In particular, peptide nucleic acid (PNA) and phosphorodiamidate morpholino oligomers linked to cationic carrier peptides are effective in time kill ...
Behmanesh, Mehrdad   +9 more
core   +2 more sources

MSFragger: ultrafast and comprehensive peptide identification in shotgun proteomics

open access: yesNature Methods, 2017
There is a need to better understand and handle the 'dark matter' of proteomics—the vast diversity of post-translational and chemical modifications that are unaccounted in a typical mass spectrometry–based analysis and thus remain unidentified.
Andy T. Kong   +4 more
semanticscholar   +1 more source

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