Results 51 to 60 of about 3,672,746 (390)
Circulating histones as clinical biomarkers in critically ill conditions
FEBS Letters, EarlyView.Circulating histones are emerging as promising biomarkers in critical illness due to their diagnostic, prognostic, and therapeutic potential. Detection methods such as ELISA and mass spectrometry provide reliable approaches for quantifying histone levels in plasma samples.
José Luis García‐Gimenez +17 more
wiley +1 more source
Zeitschrift für Kristallographie - New Crystal Structures, 2017 C68H72O10, triclinic, P1̅ (no. 2), a = 13.3619(4) Å, b = 13.9234(4) Å, c = 16.6975(5) Å, α = 96.023(2)°, β = 104.537(1)°, γ = 105.625(1)°, V = 2845.85(15) Å3, Z = 2, Rgt(F) = 0.0491, wRref(F2) = 0.1311, T = 173 K.
Samipillai Marivel +3 more
doaj +1 more source
A Comprehensive Review on Current Advances in Peptide Drug Development and Design
International Journal of Molecular Sciences, 2019 Protein–protein interactions (PPIs) execute many fundamental cellular functions and have served as prime drug targets over the last two decades. Interfering intracellular PPIs with small molecules has been extremely difficult for larger or flat binding ...
A. Lee +3 more
semanticscholar +1 more source
Foods, 2017 The increased consumer awareness of the health promoting effects of functional foods and nutraceuticals is the driving force of the functional food and nutraceutical market. Bioactive peptides are known for their high tissue affinity, specificity and efficiency in promoting health.
Eric Daliri, Deog Oh, Byong Lee
openaire +3 more sources
FEBS Letters, EarlyView.Extracellular vesicles (EVs) mediate intercellular communication in tumor immune microenvironments. However, their role in B‐cell malignancies remains poorly defined, owing to biological complexity and technical challenges in EV isolation and analysis.
Daniel Bachurski, Michael Hallek
wiley +1 more source
Regulation of the ER stress response by a mitochondrial microprotein
Nature Communications, 2019 Cells trigger an unfolded protein response (UPR) in the endoplasmic reticulum, but its regulation by mitochondria is unclear. Here, the authors report a 54-residue microprotein PIGBOS that participates in inter-organelle contact between the endoplasmic ...
Qian Chu +12 more
doaj +1 more source
Signal Transduction and Targeted Therapy, 2021 Natural killer (NK) cells have been suggested to be associated with type 2 diabetes by regulating systemic inflammation. However, the mechanism by which NK cells regulate insulin sensitivity remains unknown. This study shows that NK-derived exosomes from
Ying Wang +8 more
doaj +1 more source
Cells, 2022 Protein phosphorylation is an essential post-translational modification that regulates multiple cellular processes. Due to their low stoichiometry and ionization efficiency, it is critical to efficiently enrich phosphopeptides for phosphoproteomics ...
Jiaran Li +8 more
doaj +1 more source
Journal of Peptide Science, 2019 The protein universe as we know is composed of folded structures and intrinsic disordered regions. The latter may adopt structures upon interaction with binding partners. In addition, some proteins contain C‐terminal extensions which act as independent functional units in the context of the protein.
Benedikt Weber +2 more
openaire +4 more sources
Alloreactive cytotoxic T lymphocytes generated in the presence of viral- derived peptides show exquisite peptide and MHC specificity [PDF]
, 1993 The nature of alloreactivity to MHC molecules has been enigmatic, primarily because of the observation that allogeneic responses are considerably stronger than syngeneic responses. To better determine the specificity potential of allogeneic responses, we
Alexander-Miller, M. A. +4 more
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