Results 191 to 200 of about 15,341,682 (292)

RoseTTAFold diffusion-guided short peptide design: a case study of binders against Keap1/Nrf2. [PDF]

Comput Struct Biotechnol J
Morena F, Cencini C, Emiliani C, Martino S.   +3 more
europepmc   +1 more source

Overcoming Photodynamic Therapy Resistance: GSH‐Responsive AIE Photosensitizer‐Hydroxycamptothecin Nanoliposomes for Extrahepatic Cholangiocarcinoma

Advanced Healthcare Materials, EarlyView.
A GSH‐responsive AIE nanoplatform (TSH NPs) with RGD‐mediated tumor targeting co‐delivers a photosensitizer (TPA) and HCPT for extrahepatic cholangiocarcinoma. The system synergistically enhances PDT and chemotherapy by suppressing HIF‐1α/VEGF‐driven hypoxic adaptation, effectively overcoming PDT resistance.
Yong Qu, Tao Peng, Yating Zhang, Juanmei Cao, Birong Wang, Chuxing Chai, Zhiyuan Gao, Yiting Xu, Yifan Jin, Yuqing Wang, Zhuoxia Li, Xu Liu, Tianqi Zhao, Yufan Chen, Weimin Lv, Di Lu, Changzheng Huang, Dan Ding, Jinxiang Zhang, Min Li   +19 more
wiley   +1 more source

PepCARES: A Comprehensive Advanced Refinement and Evaluation System for Peptide Design and Affinity Screening. [PDF]

ACS Omega
Xu W, Wu Z, Zhang C, Zhu C, Duan H.
europepmc   +1 more source

Designer natriuretic peptides. [PDF]

Journal of Clinical Investigation, 1993
openaire   +1 more source

Bacteria‐Responsive Nanostructured Drug Delivery Systems for Targeted Antimicrobial Therapy

Advanced Materials, EarlyView.
Bacteria‐responsive nanocarriers are designed to release antimicrobials only in the presence of infection‐specific cues. This selective activation ensures drug release precisely at the site of infection, avoiding premature or indiscriminate release, and enhancing efficacy.
Guillermo Landa, Gracia Mendoza, Silvia Irusta, Manuel Arruebo   +3 more
wiley   +1 more source

De novo synthetic antimicrobial peptide design with a recurrent neural network. [PDF]

Protein Sci
Li C, Sutherland D, Richter A, Coombe L, Yanai A, Warren RL, Kotkoff M, Hof F, Hoang LMN, Helbing CC, Birol I.   +10 more
europepmc   +1 more source

Kelvin Probe Force Microscopy in Bionanotechnology: Current Advances and Future Perspectives

Advanced Materials, EarlyView.
Kelvin probe force microscopy (KPFM) enables the nanoscale mapping of electrostatic surface potentials. While widely applied in materials science, its use in biological systems remains emerging. This review presents recent advances in KPFM applied to biological samples and provides a critical perspective on current limitations and future directions for
Ehsan Rahimi, Mario Palacios‐Corella, Arjan Mol, Salvador Pané, Josep Puigmartí‐Luis   +4 more
wiley   +1 more source

Light-Switchable Peptides with a Hemithioindigo Unit: Peptide Design, Photochromism, and Optical Spectroscopy.

ChemPhysChem, 2016
S. Kitzig, M. Thilemann, T. Cordes, K. Rück‐Braun   +3 more
semanticscholar   +1 more source

De Novo Antimicrobial Peptide Design with Feedback Generative Adversarial Networks. [PDF]

Int J Mol Sci
Zervou MA, Doutsi E, Pantazis Y, Tsakalides P.   +3 more
europepmc   +1 more source

Mesoporous Silica Nanoparticles in Biomedicine: Advances and Prospects

Advanced Materials, EarlyView.
Mesoporous silica nanoparticles offer unique properties like high surface area, tunable pores, and functionalization. They excel in drug delivery, tissue engineering, and stimuli‐responsive therapies, enabling targeted and controlled treatments. With roles in cancer therapy and diagnostics, their clinical translation requires addressing challenges in ...
Miguel Manzano, María Vallet‐Regí
wiley   +1 more source