Nanodiamond Quantum Sensors for Probing Free Radical Biology
Advanced Functional Materials, EarlyView.Free radicals play key roles in cellular signaling and disease but remain difficult to measure in living systems. Nanodiamonds (NDs) with nitrogen‐vacancy (NV) centers enable quantum sensing of local magnetic noise via T₁ relaxometry, providing nondestructive radical detection in living cells.
Qi Lu, Yingke Wu, Tanja Weil
wiley +1 more source
Classifier-driven generative adversarial networks for enhanced antimicrobial peptide design. [PDF]
Brief BioinformZervou MA +3 more
europepmc +1 more source
Expanding the Landscape of Amino Acid-Rich Antimicrobial Peptides: Definition, Deployment in Nature, Implications for Peptide Design and Therapeutic Potential. [PDF]
Int J Mol Sci, 2022 Decker AP, Mechesso AF, Wang G.
europepmc +1 more source
Advanced Functional Materials, EarlyView.We present a tissue‐stimulator platform for seamless electrode integration with pancreatic tissue, applying uniform electrical stimulation through optimized design with biohybrid 3D printing. Advantageous effects of electrical stimulation on β‐cell function were observed, including enhanced calcium signaling, islet morphology, and maturation.
Jihwan Kim +7 more
wiley +1 more source
A Multi-Property Optimizing Generative Adversarial Network for de novo Antimicrobial Peptide Design. [PDF]
Adv Sci (Weinh)Liu J +16 more
europepmc +1 more source
Investigating Active Learning and Meta-Learning for Iterative Peptide Design. [PDF]
J Chem Inf Model, 2021 Barrett R, White AD.
europepmc +1 more source
Multiplex Modular Nanorobotic Systems with Catalytic Activity under Magnetic Navigation
Advanced Functional Materials, EarlyView.We present modular nanorobots composed of a magnetic propulsion module and different extension modules carrying functional activities, assembled via DNA base pairing. The system integrates propulsion, optical tracking, enzymatic catalysis, and cell docking in a programmable manner.
Voichita Mihali +7 more
wiley +1 more source
Understanding Biases in Liquid-Liquid Phase Separation: Investigating Amino Acid Enrichments in Phase-Separating Proteins toward Peptide Design. [PDF]
BiomacromoleculesCalvário J +5 more
europepmc +1 more source
Synthetic pro-peptide design to enhance the secretion of heterologous proteins by Saccharomyces cerevisiae. [PDF]
Microbiologyopen, 2022 Cho JS +7 more
europepmc +1 more source
Biocompatible but Antibacterial Mechanism of Graphene Oxide for Sustainable Antibiotics
Advanced Functional Materials, EarlyView.Graphene oxide (GO) exhibits selective antibacterial activity through specific interactions between its oxygen functional groups and bacterial membrane phospholipid POPG, causing membrane destabilization while maintaining biocompatibility. Model membrane studies and infected wound models in mice and pigs demonstrate effective bacterial suppression and ...
Sujin Cha +15 more
wiley +1 more source