Epitope mapping using mRNA display and a unidirectional nested deletion library [PDF]
, 2005 In vitro selection targeting an anti-polyhistidine monoclonal antibody was performed using mRNA display with a random, unconstrained 27-mer peptide library.
Ja, William W. +2 more
core +1 more source
MethodsX, 2021 The semenogelin 1 protein is secreted in the seminal vesicles. After ejaculation it is split into small peptide fragments using internal proteases.
Aydar Bikmullin +3 more
doaj +1 more source
Nature Communications, 2022 Peptide fragments derived from the interfaces of protein-protein interactions (PPIs) provide useful templates for designing small molecule PPI inhibitors.
Xiyao Cheng +8 more
doaj +1 more source
Accurate Peptide Fragment Mass Analysis: Multiplexed Peptide Identification and Quantification [PDF]
Journal of Proteome Research, 2012 Fourier transform-all reaction monitoring (FT-ARM) is a novel approach for the identification and quantification of peptides that relies upon the selectivity of high mass accuracy data and the specificity of peptide fragmentation patterns. An FT-ARM experiment involves continuous, data-independent, high mass accuracy MS/MS acquisition spanning a ...
Chad R, Weisbrod +4 more
openaire +2 more sources
Comparative Analysis of the Major Polypeptides from Liver Gap Junctions and Lens Fiber Junctions [PDF]
, 1982 Gap junctions from rat liver and fiber junctions from bovine lens have similar septilaminar profiles when examined by thin-section electron microscopy and differ only slightly with respect to the packing of intramembrane particles in freeze-fracture ...
Anderson, David J. +3 more
core +2 more sources
NEXAFS spectroscopy and site-specific fragmentation of N -methylformamide, N,N -dimethylformamide, and N,N -dimethylacetamide [PDF]
, 2016 Near-edge X-ray absorption fine-structure (NEXAFS) spectra measured at the C, N, and O K-edges for three molecules containing the amide moiety, N-methylformamide (HCONHCH3), N,Ndimethylformamide (HCON(CH3)2), and N,N-dimethylacetamide (CH3CON(CH3)2 ...
Alagia, Michele +7 more
core +1 more source
UV-induced ligand exchange in MHC class I protein crystals [PDF]
, 2009 High-throughput structure determination of protein−ligand complexes is central in drug development and structural proteomics. To facilitate such high-throughput structure determination we designed an induced replacement strategy.
Adams P. D. +32 more
core +1 more source
Fibrillisation of hydrophobically modified amyloid peptide fragments in an organic solvent [PDF]
, 2007 The self-assembly of a hydrophobically modified fragment of the amyloid beta(A beta) peptide has been studied in methanol. The peptide FFKLVFF is based on A beta(16-20) extended at the N terminus by two phenylalanine residues.
Castelletto, Valeria +2 more
core +1 more source
Unusual fragmentation of derivatized cysteine‐containing peptides [PDF]
Rapid Communications in Mass Spectrometry, 2018 Rationale Modification of cysteines by aminoethylation results in side chains similar to those of lysine. Trypsin cleaves at this modified residue and this labeling method can facilitate the analysis of proteins, specifically antibodies.
Nick Degraan‐Weber +2 more
openaire +2 more sources
Method of treating endothelial dysfunction comprising administration of a thrombin peptide derivative [PDF]
, 2012 Endothelial dysfunction (ED) is associated with a number of diseases and disorders. Agonists of the non-proteolytically activated thrombin receptor can be used in methods to treat ED or ED-related diseases and disorders.Board of Regents, University of ...
Carney, Darrell H. +2 more
core +1 more source