Results 51 to 60 of about 355,998 (353)

Reactivity of anti-thyroid antibodies to thyroglobulin tryptic fragments: comparison of autoimmune and non-autoimmune thyroid diseases

open access: yesBrazilian Journal of Medical and Biological Research, 1999
Studies concerning the antigenicity of thyroglobulin fragments allow the characterization of the epitopes but do not consider the role of heavier antigenic fragments that could result in vivo from the action of endoproteases.
L.H.B. Boechat, R.L. Zollner
doaj   +1 more source

Peptide binding affinity redistributes preassembled repeat protein fragments [PDF]

open access: yes, 2019
Designed armadillo repeat proteins (dArmRPs) are modular peptide binders composed of N- and C-terminal capping repeats Y and A and a variable number of internal modules M that each specifically recognize two amino acids of the target peptide ...
Zerbe, Oliver; https://orcid.org/   +2 more
core   +1 more source

Chronological Profiling of Plasma Native Peptides after Hepatectomy in Pigs: Toward the Discovery of Human Biomarkers for Liver Regeneration. [PDF]

open access: yesPLoS ONE, 2017
Liver regeneration after partial hepatectomy (PHx) is a time-dependent process, which is tightly regulated by multiple signaling cascades. Failure of this complex process leads to posthepatectomy liver failure (PHLF), which is associated with a high rate
Kohta Iguchi   +17 more
doaj   +1 more source

The synthesis of an analogue of the locust CRF-like diuretic peptide, and the biological activities of this and some C-terminal fragments.

open access: yes, 2003
The synthesis is described of an analogue of the locust CRF-like diuretic peptide in which methionine in positions 1,3, and 13 is replaced by isosteric methyl-homoserine residues.
Simmonds, M.S.J.   +5 more
core   +1 more source

Mapping of residues of fibrinogen cleaved by protease II of Bacillus thuringiensis var. israelensis IMV B-7465 [PDF]

open access: yesThe Ukrainian Biochemical Journal, 2016
The limited proteolysis of macromolecules allows obtaining the fragments that preserve the structure and functional properties of the whole molecule and could be used in the study of proteins structure and function.
E. M. Stohniy   +8 more
doaj   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

open access: yesFEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe   +3 more
wiley   +1 more source

Immunomodulatory and neurotropic activities of synthetic peptides in a model of brain injury in rats

open access: yesМедицинская иммунология, 2023
Treatment of consequences of traumatic brain injury (TBI) remains one of the current problems of medicine. To increase the effectiveness of treatment of post-traumatic complications, various drugs are recommended, including the peptide with ...
N. B. Serebryanaya   +5 more
doaj   +1 more source

Effects of ACTH peptide fragments on memory formation [PDF]

open access: yesPharmacology Biochemistry and Behavior, 1976
The effects of peptides derived from ACTH on the formation of long-term memory have been investigated in male mice. Post-training administration of ACTH 4-10-L-Phe-7 (ACTH-L) improved retention for both passive and active avoidance tasks. Administration of ACTH 4-10-D-Phe-7 (ACTH-D) impaired retention for both tasks.
J F, Flood   +3 more
openaire   +2 more sources

Peptide fragments of BoNT/A light chain.

open access: yes, 2013
Diagram is drawn to scale to facilitate size and location comparison between peptide fragments. Peptide fragments were expressed as fusions to GST at the N-terminal. N- and C-terminal amino acids of each peptide fragment are indicated.
Miles C. Scotcher (364136)   +3 more
core   +1 more source

Signal peptide peptidases and gamma-secretase: Cousins of the same protease family? [PDF]

open access: yes, 2007
Signal peptide peptidase (SPIP) is an unusual aspartyl protease, which mediates clearance of signal peptides by proteolysis within the endoplasmic reticulum (ER).
Fluhrer, Regina, Haass, Christian
core   +1 more source

Home - About - Disclaimer - Privacy