Results 51 to 60 of about 527,353 (294)

ECD-like peptide fragmentation at atmospheric pressure [PDF]

open access: yesInternational Journal of Mass Spectrometry, 2012
Fragmentation of multiply-charged peptide ions via interaction with products of gas discharge at atmospheric pressure conditions was studied using ion mobility separation - fragmentation cell - linear ion trap mass spectrometer. The observed fragmentation spectra mainly consisted of c- type ions that are specific to electron capture dissociation ...
Vadym D, Berkout, Vladimir M, Doroshenko
openaire   +2 more sources

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

open access: yesFEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho   +3 more
wiley   +1 more source

Selected Reaction Monitoring (SRM) frente a Western Blot [PDF]

open access: yes, 2016
We propose the SRM technology as a complementary method to the Western Blot for the detection and quantification of proteins in a sample. The technique Western Blot has its own limitations: i) only a protein-of-choice is detected, ignoring any non ...
Heredia Ponce, Zaira Maria   +1 more
core  

Distinct Intracellular Compartments Involved in Invariant Chain Degradation and Antigenic Peptide Loading of Major Histocompatibility Complex (MHC) Class II Molecules [PDF]

open access: yes, 1997
Major histocompatibility complex (MHC) class II molecules are transported to intracellular MHC class II compartments via a transient association with the invariant chain (Ii).
Ferrari, G.   +3 more
core   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

open access: yesFEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe   +3 more
wiley   +1 more source

Digestion of Protein in Premature and Term Infants. [PDF]

open access: yes, 2012
Premature birth rates and premature infant morbidity remain discouragingly high. Improving nourishment for these infants is the key for accelerating their development and decreasing disease risk. Dietary protein is essential for growth and development of
Dallas, David C   +3 more
core   +2 more sources

Characterization of Trypsin-Like Protease of Lactobacillus plantarum FNCC 0270

open access: yesHayati Journal of Biosciences, 2014
Trypsin is an enzyme that has a unique mechanism of cutting peptide bonds specifically at the carboxyl side of lysine or arginine amino acids, with another amino acid.
Trismilah Margono   +3 more
doaj   +1 more source

Immunomodulatory and neurotropic activities of synthetic peptides in a model of brain injury in rats

open access: yesМедицинская иммунология, 2023
Treatment of consequences of traumatic brain injury (TBI) remains one of the current problems of medicine. To increase the effectiveness of treatment of post-traumatic complications, various drugs are recommended, including the peptide with ...
N. B. Serebryanaya   +5 more
doaj   +1 more source

Lipid-Induced β-Amyloid Peptide Assemblage Fragmentation [PDF]

open access: yesBiophysical Journal, 2006
Alzheimer's disease is the most common cause of dementia and is widely believed to be due to the accumulation of beta-amyloid peptides (Abeta) and their interaction with the cell membrane. Abetas are hydrophobic peptides derived from the amyloid precursor proteins by proteolytic cleavage.
Widenbrant, Martin J.O.   +3 more
openaire   +2 more sources

Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions

open access: yesFEBS Letters, EarlyView.
We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva   +10 more
wiley   +1 more source

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