Results 11 to 20 of about 343,994 (261)

Identification of Immune-Active Peptides in Casein Hydrolysates and Its Transport Mechanism on a Caco-2 Monolayer

open access: yesFoods, 2023
In this study, we investigated the transport mechanism of immune-active peptide fragments isolated from casein gastrointestinal hydrolysates via a Caco-2 monolayer.
Haiyan Xue   +7 more
doaj   +1 more source

Study on the reduction of Tartary buckwheat allergenicity during Pediococcus pentosaceus fermentation by HPLC-MS/MS analysis

open access: yesFood Chemistry: X, 2023
Tartary buckwheat contains more valuable nutrients than common buckwheat, but it also contains allergenic proteins that induce allergic reactions through an IgE-mediated response.
Yiming Zhou   +3 more
doaj   +1 more source

Isolation of recombinant phage antibodies targeting the hemagglutinin cleavage site of highly pathogenic avian influenza virus. [PDF]

open access: yesPLoS ONE, 2013
Highly pathogenic avian influenza (HPAI) H5N1 viruses, which have emerged in poultry and other wildlife worldwide, contain a characteristic multi-basic cleavage site (CS) in the hemagglutinin protein (HA).
Jinhua Dong   +5 more
doaj   +1 more source

The N-terminal region of photocleavable peptides that bind HLA-DR1 determines the kinetics of fragment release. [PDF]

open access: yesPLoS ONE, 2018
Major Histocompatibility Complex class II (MHC-II) molecules bind peptides and present them to receptors on CD4+ T cells as part of the immune system's surveillance of pathogens and malignancy.
Maria Pia Negroni, Lawrence J Stern
doaj   +1 more source

Peptide and peptide-inspired checkpoint inhibitors: Protein fragments to cancer immunotherapy

open access: yesMedicine in Drug Discovery, 2020
Immune system regained the attention of oncologists and has entered the mainstream for cancer therapy since the discovery of checkpoint antibodies targeting CTLA4 and PD-1 pathways.
Pottayil G. Sasikumar   +1 more
doaj   +1 more source

Fragmentation of amidinated peptide ions [PDF]

open access: yesJournal of the American Society for Mass Spectrometry, 2004
The collision-induced dissociation characteristics of amidinated and unmodified tryptic peptides are compared using an ion trap mass spectrometer with both electrospray ionization and matrix-assisted laser/desorption ionization (MALDI). Several fragmentation pathways in a number of tryptic peptides of various precursor charge states are found to be ...
Beardsley, Richard L, Reilly, James P
openaire   +2 more sources

From Synthetic Fragments of Endogenous Three-Finger Proteins to Potential Drugs

open access: yesFrontiers in Pharmacology, 2019
The proteins of the Ly6 family have a three-finger folding as snake venom α-neurotoxins, targeting nicotinic acetylcholine receptors (nAChRs), and some of them, like mammalian secreted Ly6/uPAR protein (SLURP1) and membrane-attached Ly-6/neurotoxin ...
Elena V. Kryukova   +11 more
doaj   +1 more source

The Synthetic Antimicrobial Peptide 19-2.5 Interacts with Heparanase and Heparan Sulfate in Murine and Human Sepsis.

open access: yesPLoS ONE, 2015
Heparanase is an endo-β-glucuronidase that cleaves heparan sulfate side chains from their proteoglycans. Thereby, heparanase liberates highly potent circulating heparan sulfate-fragments (HS-fragments) and triggers the fatal and excessive inflammatory ...
Lukas Martin   +8 more
doaj   +1 more source

A Novel Urinary Proteomics Classifier for Non-Invasive Evaluation of Interstitial Fibrosis and Tubular Atrophy in Chronic Kidney Disease

open access: yesProteomes, 2021
Non-invasive urinary peptide biomarkers are able to detect and predict chronic kidney disease (CKD). Moreover, specific urinary peptides enable discrimination of different CKD etiologies and offer an interesting alternative to invasive kidney biopsy ...
Lorenzo Catanese   +6 more
doaj   +1 more source

The data of heterologous expression protocol for synthesis of 15N, 13C-labeled SEM1(68-107) peptide fragment of homo sapiens semenogelin 1

open access: yesMethodsX, 2021
The semenogelin 1 protein is secreted in the seminal vesicles. After ejaculation it is split into small peptide fragments using internal proteases.
Aydar Bikmullin   +3 more
doaj   +1 more source

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