Results 11 to 20 of about 527,353 (294)

Peptide‐Guided Assembly of Repeat Protein Fragments [PDF]

Angewandte Chemie International Edition, 2018
AbstractHerein, we present the peptide‐guided assembly of complementary fragments of designed armadillo repeat proteins (dArmRPs) to create proteins that bind peptides not only with high affinity but also with good selectivity. We recently demonstrated that complementary N‐ and C‐terminal fragments of dArmRPs form high‐affinity complexes that resemble ...
Michel, Erich, Plückthun, Andreas, Zerbe, Oliver   +2 more
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Peptide Extracts from Seven Medicinal Plants Discovered to Inhibit Oomycete Phytophthora infestans, a Causative Agent of Potato Late Blight Disease

Plants, 2020
We report the inhibitory effect of peptide extracts obtained from seven medicinal plants against a causative agent of late blight disease Phytophthora infestans.
Eugene A. Rogozhin, Alexey S. Vasilchenko, Anna S. Barashkova, Alexey N. Smirnov, Sergey K. Zavriev, Vladimir P. Demushkin   +5 more
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Hit-to-Lead Short Peptides against Dengue Type 2 Envelope Protein: Computational and Experimental Investigations

Molecules, 2022
Data from the World Health Organisation show that the global incidence of dengue infection has risen drastically, with an estimated 400 million cases of dengue infection occurring annually.
Norburhanuddin Johari Zaidi, Adib Afandi Abdullah, Choon Han Heh, Chun-Hung Lin, Rozana Othman, Abdullah Al Hadi Ahmad Fuaad   +5 more
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Spatial Structure and Activity of Synthetic Fragments of Lynx1 and of Nicotinic Receptor Loop C Models

Biomolecules, 2020
Lynx1, membrane-bound protein co-localized with the nicotinic acetylcholine receptors (nAChRs) and regulates their function, is a three-finger protein (TFP) made of three β-structural loops, similarly to snake venom α-neurotoxin TFPs.
Konstantin S. Mineev, Elena V. Kryukova, Igor E. Kasheverov, Natalia S. Egorova, Maxim N. Zhmak, Igor A. Ivanov, Dmitry A. Senko, Alexey V. Feofanov, Anastasia A. Ignatova, Alexander S. Arseniev, Yuri N. Utkin, Victor I. Tsetlin   +11 more
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Fragmentation of amidinated peptide ions [PDF]

Journal of the American Society for Mass Spectrometry, 2004
The collision-induced dissociation characteristics of amidinated and unmodified tryptic peptides are compared using an ion trap mass spectrometer with both electrospray ionization and matrix-assisted laser/desorption ionization (MALDI). Several fragmentation pathways in a number of tryptic peptides of various precursor charge states are found to be ...
Beardsley, Richard L, Reilly, James P
openaire   +2 more sources

Identification of Immune-Active Peptides in Casein Hydrolysates and Its Transport Mechanism on a Caco-2 Monolayer

Foods, 2023
In this study, we investigated the transport mechanism of immune-active peptide fragments isolated from casein gastrointestinal hydrolysates via a Caco-2 monolayer.
Haiyan Xue, Jingjing Han, Jun Ma, Hongxin Song, Baoyuan He, Xiaofeng Liu, Meixia Yi, Lei Zhang   +7 more
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Isolation of recombinant phage antibodies targeting the hemagglutinin cleavage site of highly pathogenic avian influenza virus. [PDF]

PLoS ONE, 2013
Highly pathogenic avian influenza (HPAI) H5N1 viruses, which have emerged in poultry and other wildlife worldwide, contain a characteristic multi-basic cleavage site (CS) in the hemagglutinin protein (HA).
Jinhua Dong, Akira Sakurai, Namiko Nomura, Enoch Y Park, Futoshi Shibasaki, Hiroshi Ueda   +5 more
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Study on the reduction of Tartary buckwheat allergenicity during Pediococcus pentosaceus fermentation by HPLC-MS/MS analysis

Food Chemistry: X, 2023
Tartary buckwheat contains more valuable nutrients than common buckwheat, but it also contains allergenic proteins that induce allergic reactions through an IgE-mediated response.
Yiming Zhou, Siyuan Yu, Xuanming She, Xiaoli Zhou   +3 more
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Light-Induced Orthogonal Fragmentation of Crosslinked Peptides [PDF]

JACS Au, 2023
Crosslinking mass spectrometry provides pivotal information on the structure and interaction of proteins. MS-cleavable crosslinkers are regarded as a cornerstone for the analysis of complex mixtures. Yet they fragment under similar conditions as peptides, leading to mixed fragmentation spectra of the crosslinker and peptide.
Lars Kolbowski, Adam Belsom, Ana M. Pérez-López, Tony Ly, Juri Rappsilber   +4 more
openaire   +4 more sources

The N-terminal region of photocleavable peptides that bind HLA-DR1 determines the kinetics of fragment release. [PDF]

PLoS ONE, 2018
Major Histocompatibility Complex class II (MHC-II) molecules bind peptides and present them to receptors on CD4+ T cells as part of the immune system's surveillance of pathogens and malignancy.
Maria Pia Negroni, Lawrence J Stern
doaj   +1 more source