Mechanical characteristics of beta sheet-forming peptide hydrogels are dependent on peptide sequence, concentration and buffer composition [PDF]
Self-assembling peptide hydrogels can be modified regarding their biodegradability, their chemical and mechanical properties and their nanofibrillar structure. Thus, self-assembling peptide hydrogels might be suitable scaffolds for regenerative therapies
Franziska Koch +9 more
doaj +3 more sources
Understanding the multifaceted nature of peptide hydrogels in biomedical research
Hydrogels are networks of three-dimensional cross-linked polymers, which possess the capacity to absorb and retain water. Hydrogels have proven to be adaptable and versatile, making them useful in various biomedical applications such as tissue
Srestha Ghosh +3 more
doaj +2 more sources
Dynamic Covalent Dextran Hydrogels as Injectable, Self-adjuvating Peptide Vaccine Depots [PDF]
Dextran-based hydrogels are promising therapeutic materials for drug delivery, tissue regeneration devices, and cell therapy vectors, due to their high biocompatibility, along with their ability to protect and release active therapeutic agents.
Bowen, Fan +4 more
core +2 more sources
In light of the increasing levels of antibiotic resistance, nanomaterials and novel biologics are urgently required to manage bacterial infections. To date, commercially available self-assembling peptide hydrogels have not been studied extensively for ...
Marina E. Afami +5 more
doaj +1 more source
Controlling the self-assembly and material properties of β-sheet peptide hydrogels by modulating intermolecular interactions [PDF]
Self-assembling peptides are a promising biomaterial with potential applications in medical de-vices and drug delivery. In the right combination of conditions, self-assembling peptides can form self-supporting hydrogels.
Steven, Maude +5 more
core +1 more source
Antimicrobial Peptide Functionalized Mesoporous Hydrogels [PDF]
Antimicrobial peptides (AMPs) are seen as a promising replacement to conventional antibiotics for the prevention of skin wound infections. However, due to the short half-life of AMPs in biological environments, such as blood, their use in clinical applications has been limited.
Saba Atefyekta +8 more
openaire +4 more sources
Covalent co-assembly between resilin-like polypeptide and peptide amphiphile into hydrogels with controlled nanostructure and improved mechanical properties [PDF]
Covalent co-assembly holds great promise for the fabrication of hydrogels with controllable nanostructure, versatile chemical composition, and enhanced mechanical properties given its relative simplicity, high efficiency, and bond stability.
Mata, Alvaro +7 more
core +4 more sources
Peptide- and Protein-Based Hydrogels [PDF]
Hydrogels are polymeric networks, capable of absorbing large amounts of water and biological fluids. They are insoluble due to the presence of chemical or physical cross-links between the constituents. Hydrogels are promising materials for use as injectable biomaterials due to their high water content, tunable viscoelasticity, and biocompatibility ...
Jonker, A.M. +3 more
openaire +1 more source
In this study, we prepared antibacterial hydrogels through the self-assembly of naphthyl anthranilamide (NaA) capped amino acid based cationic peptide mimics. These ultra-short cationic peptide mimics were rationally designed with NaA as a capping group,
Vina R. Aldilla +8 more
doaj +1 more source
Self‐Assembling Peptide‐Based Hydrogels for Wound Tissue Repair
Wound healing is a long‐term, multistage biological process that includes hemostasis, inflammation, proliferation, and tissue remodeling and requires intelligent designs to provide comprehensive and convenient treatment.
Tong Guan +3 more
doaj +1 more source

