Results 41 to 50 of about 30,187 (256)
Bottom-up assembly of hydrogels from bacteriophage and Au nanoparticles: the effect of cis- and trans-acting factors. [PDF]
PLoS ONE, 2008 Hydrogels have become a promising research focus because of their potential for biomedical application. Here we explore the long-range, electrostatic interactions by following the effect of trans-acting (pH) and cis-acting factors (peptide mutation) on ...
Glauco R Souza +8 more
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Self-Assembly of a Dentinogenic Peptide Hydrogel [PDF]
ACS Omega, 2018 Current standard of care for treating infected dental pulp, root canal therapy, retains the physical properties of the tooth to a large extent, but does not aim to rejuvenate the pulp tissue. Tissue-engineered acellular biomimetic hydrogels have great potential to facilitate the regeneration of the tissue through the recruitment of autologous stem ...
Peter K. Nguyen +7 more
openaire +3 more sources
Hydrogelation tunability of bioinspired short peptides
Soft Matter, 2022 The fragment 269–273 of nucleophosmin 1 protein, was investigated in its ability to form hydrogels in four different forms deriving from the partial, absent and complete amidation/acetylation at the extremities of the backbone.
Sara La Manna +6 more
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Peptide-Based Supramolecular Hydrogels as Drug Delivery Agents: Recent Advances
Gels, 2022 Supramolecular peptide hydrogels have many important applications in biomedicine, including drug delivery applications for the sustained release of therapeutic molecules.
Carlos B. P. Oliveira +4 more
doaj +1 more source
Peptide-directed self-assembly of hydrogels [PDF]
Acta Biomaterialia, 2009 This review focuses on the self-assembly of macromolecules mediated by the biorecognition of peptide/protein domains. Structures forming alpha-helices and beta-sheets have been used to mediate self-assembly into hydrogels of peptides, reactive copolymers and peptide motifs, block copolymers, and graft copolymers.
Jindrich, Kopecek, Jiyuan, Yang
openaire +2 more sources
Gels, 2023 Multicomponent hydrogels (HGs) based on ultrashort aromatic peptides have been exploited as biocompatible matrices for tissue engineering applications, the delivery of therapeutic and diagnostic agents, and the development of biosensors.
Sabrina Giordano +9 more
doaj +1 more source
RNA extraction from self-assembling peptide hydrogels to allow qPCR analysis of encapsulated cells.
PLoS ONE, 2018 Self-assembling peptide hydrogels offer a novel 3-dimensional platform for many applications in cell culture and tissue engineering but are not compatible with current methods of RNA isolation; owing to interactions between RNA and the biomaterial.
Kyle A Burgess +5 more
doaj +1 more source
Materials Today BioCompletely synthetic cell cultivation materials for human pluripotent stem cells (hPSCs) are important for the future clinical use of hPSC-derived cells.
Tzu-Cheng Sung +9 more
doaj +1 more source
Peptide-Based Hydrogels and Nanogels for Delivery of Doxorubicin
International Journal of Nanomedicine, 2021 The clinical use of the antitumoral drug doxorubicin (Dox) is reduced by its dose-limiting toxicity, related to cardiotoxic side effects and myelosuppression. In order to overcome these drawbacks, here we describe the synthesis, the structural characterization and the in vitro cytotoxicity assays of hydrogels (HGs) and nanogels (NGs) based on short ...
Gallo E. +5 more
openaire +6 more sources
Hydrogels from the Assembly of SAA/Elastin-Inspired Peptides Reveal Non-Canonical Nanotopologies
Molecules, 2022 Peptide-based hydrogels are of great interest in the biomedical field according to their biocompatibility, simple structure and tunable properties via sequence modification.
Alessandra Scelsi +5 more
doaj +1 more source