Results 51 to 60 of about 30,187 (256)

Recent research of peptide-based hydrogel in nervous regeneration

Bioactive Materials
Neurological disorders exert significantly affect the quality of life for patients, necessitating effective strategies for nerve regeneration. Both traditional autologous nerve transplantation and emerging therapeutic approaches encounter scientific ...
Chunmei Xie, Yueyang Chen, Lang Wang, Kin Liao, Bin Xue, Yulong Han, Lan Li, Qing Jiang   +7 more
doaj   +1 more source

A peptidic hydrogel that may behave as a “Trojan Horse” [PDF]

Beilstein Journal of Organic Chemistry, 2013
A physical hydrogel prepared with the low-molecular-weight hydrogelator (LMWHG) CH2(C3H6CO-L-Phe-D-Oxd-OH)2 and water/ethanol mixture was applied as a potential “Trojan Horse” carrier into cells. By SEM and XRD analysis we could demonstrate that a fibrous structure is present in the xerogel, making a complex network. The gelator is derived from α-amino
CASTELLUCCI, NICOLA, SARTOR, GIORGIO, CALONGHI, NATALIA, PAROLIN, CAROLA ELEONORA, FALINI, GIUSEPPE, TOMASINI, CLAUDIA   +5 more
openaire   +5 more sources

GelMA‐based 3D spheroids recapitulate transcriptomic and functional hallmarks of myeloid sarcoma

FEBS Open Bio, EarlyView.
GelMA 5% hydrogels support the formation of myeloid leukemia spheroids that recapitulate MS‐specific features, including G1 arrest, apoptosis, and ECM‐driven transcriptomic reprogramming. The 3D model mimicked soft‐tissue‐like stiffness and oxygen conditions, and transcriptomic convergence with primary MS samples confirmed its utility as a preclinical ...
Nicolas Germain, Elise Buret, Le Hoang Thanh Nguyen, Marion Cocheteux, Nicolas Touya, Mélanie Dhayer, Romain Dubois, Frank Lafont, Sebastien Janel, Patrice Maboudou, Steve Lancel, Philippe Marchetti   +11 more
wiley   +1 more source

Intrinsic Photoactive Star ZnPc–Poly(glutamate) Nanoplatforms for Multimodal Glioblastoma Therapy and Brain‐Targeted Delivery

Advanced Functional Materials, EarlyView.
An intrinsic photoactive star‐shaped zinc phtalocyanine‐poly(L‐glutamic acid) (ZnPc‐PGA) nanoplatform for multimodal glioblastoma (GBM) therapy and brain‐targeted elivery. A ZnPc‐PGA‐based multifunctional theranostic nanocarrier platform enables image‐guided, multimodal GBM therapy. ZnPc‐PGA nanocarriers support the integration of fluorescence imaging,
Amina Benaicha‐Fernández, Teodora Ranđelović, Ana Armiñán, Víctor Sebastián, Manuel Fuentes, Cristián Huck‐Iriart, Esther Masiá, Paula Carrascosa‐Marco, Pablo Juanes‐Velasco, Snežana Đorđević, Clara Bayona, Ignacio Ochoa, Maria Medel, Inmaculada Conejos‐Sánchez, María J. Vicent   +14 more
wiley   +1 more source

Nanotechnology in Drug Delivery: Anatomy and Molecular Insight into the Self-Assembly of Peptide-Based Hydrogels

Molecules
The bioavailability, release, and stability of pharmaceuticals under physicochemical conditions is the major cause of drug candidates failing during their clinical trials.
Adelaide R. Mashweu, Vladimir A. Azov
doaj   +1 more source

Therapeutic potential of a pullulan polysaccharide-based hydrogel with antibacterial peptide for skin wound healing [PDF]

Iranian Journal of Basic Medical Sciences
Objective(s): Eliminating skin defects using scaffolds, especially hydrogels, has been a promising method to accelerate regeneration. The utilization of hydrogels composed of carboxymethyl chitosan and pullulan oxide, synthesized via Schiff base reaction,
Maziar Malekzadeh, Mehrdad Mousazadeh Moghaddam, Masoud Ghorbani   +2 more
doaj   +1 more source

Chemically Fueled Systems Chemistry Across Length Scales

Advanced Functional Materials, EarlyView.
Chemically fueled reaction cycles regulate processes through single and multiple catalytic sites on the molecular and assembly scale. This gives rise to unique kinetically controlled properties/functions like spatio‐temporal catalysis, oscillations, optical properties, and perform work.
Brigitte A. K. Kriebisch, Job Boekhoven
wiley   +1 more source

Advances in preparation and application of antibacterial hydrogels

Journal of Nanobiotechnology, 2023
Bacterial infections, especially those caused by drug-resistant bacteria, have seriously threatened human life and health. There is urgent to develop new antibacterial agents to reduce the problem of antibiotics.
Yixin Tang, Huiqing Xu, Xue Wang, Shuhan Dong, Lei Guo, Shichen Zhang, Xi Yang, Chang Liu, Xin Jiang, Mujie Kan, Shanli Wu, Jizhou Zhang, Caina Xu   +12 more
doaj   +1 more source

Sulfation‐Tunable Peptide‐Glycosaminoglycan Hydrogels for Hematopoietic Stem and Progenitor Cell Expansion

Advanced Functional Materials, EarlyView.
Co‐assembly of rationally designed glycosaminoglycan‐binding peptides with sulfated glycosaminoglycans yields supramolecular hydrogels with tunable mechanics and matrix‐mediated cytokine retention. The glycosaminoglycans thereby act as cofactors, driving a coil‐to‐β‐sheet transition that triggers gelation.
Shirel Veretnik, Prannoy Seth, Maximilian Fusenig, Jens Friedrichs, Nicole Fertala, Passant Atallah, Uwe Freudenberg, Ayala Lampel, Carsten Werner   +8 more
wiley   +1 more source

3D coaxial bioprinting of RADA16-I self-assembling peptide hydrogel

Materials Today Bio
Peptides that self-assemble into hydrogels provide a dynamic microenvironment for various cell types. Combining top-down extrusion 3D bioprinting with bottom-up self-assembly of peptide hydrogels offers an innovative approach to biofabrication.
M. Jergitsch, S. Perez-Amodio, L.M. Delgado, R.A. Perez, M.A. Mateos-Timoneda   +4 more
doaj   +1 more source