Results 171 to 180 of about 60,986 (298)

Polyesterase activity and thermostability of carboxylesterases from Thermoleophilum album YS‐3

The FEBS Journal, EarlyView.
Three novel α/β‐hydrolases from thermophilic bacterium Thermoleophilum album display carboxylesterase and polyesterase activity. These enzymes hydrolyse PET, PLA and PCL both at high and moderate temperatures. TA21 shows superior activity, efficiently converting MHET to terephthalic acid. Structural features underlying substrate binding highlight their
Tatyana N. Chernikova, Anna N. Khusnutdinova, Hairong Ma, Manuel Ferrer, Olga V. Golyshina, Alexander F. Yakunin, Peter N. Golyshin   +6 more
wiley   +1 more source

Characterization of hydrolase activity in ocular tissues of humans and preclinical species. [PDF]

Drug Metab Dispos
Li M, Zhang D, Jones RS, Cheruzel L, Khojasteh SC, Chen HH, Adaligil E, Shwani T, Owen LA, Kim IK, DeAngelis MM, Ma B.   +11 more
europepmc   +1 more source

Investigating transthyretin variants H88R and I107V in amyloid priming: From destabilization to complete dissociation

The FEBS Journal, EarlyView.
Investigated mutations in transthyretin (TTR) disrupt the F87‐centered hydrophobic core that stabilizes its tetrameric structure. The mild I107V mutation weakens inter‐chain packing, while H88R fully abolishes tetramer formation, yielding a monomeric, aggregation‐prone form. Structural, biophysical, and computational analyses reveal that both mutations
István L. Bódy, Zsolt Fazekas, Nóra Wágner, Anna J. Kiss‐Szemán, Veronika Harmat, Zoltán Pozsonyi, Dóra K. Menyhárd, András Perczel   +7 more
wiley   +1 more source

Mechanism and evolutionary divergence of a novel oxidized polyvinyl alcohol hydrolase in Stenotrophomonas rhizophila QL-P4. [PDF]

Sci Rep
Zhou Y, Bold N, Feng J, Jia C, Huang K, Yao Y, Qiu L, Chen S, Huang L, Wei Y.   +9 more
europepmc   +1 more source

Proteolysis at the extracellular matrix interface: Molecular architects and regulators in health and disease

The FEBS Journal, EarlyView.
The extracellular matrix (ECM) is a dynamic scaffold that orchestrates tissue architecture and cellular communication. A critical but underexplored interplay between proteases and cluster of differentiation molecules (CD) governs ECM turnover and directs cell fate.
David Jurnečka, Matija Hrovatin, Bor Bokalj, Boris Turk   +3 more
wiley   +1 more source

The adaptive nature of the foam proteome produced by Mahanarva spectabilis (Hemiptera: Cercopidae) when infesting forage grasses with different levels of antibiosis-type resistance. [PDF]

Sci Rep
José Rinaldi A, Silva Bonjour M, Barros E, Machado Auad A, Teixeira Bhering Faria G, Almeida Oliveira MG, Josué de Oliveira Ramos H, Fernando Pereira J.   +7 more
europepmc   +1 more source

Tree growth response and adaptation to climate change and climate extremes: From canopy to stem

Journal of Integrative Plant Biology, EarlyView.
This review synthesizes the responses and adaptations of tree growth, including canopy phenology, intra‐annual wood formation dynamics, and annual stem growth, to climate change and climate extremes. It highlights key knowledge gaps for future research to support sustainable forest management and enhance forest carbon storage under ongoing climate ...
Feiyu Yang, Leyao Zhu, Jiahao Cao, Fei Yang, Borbála Codogno, Qianqian Ma, Hanxue Liang, Wenjin Wang, Jian‐Guo Huang   +8 more
wiley   +1 more source

Lysosomal dysfunction in diabetes and diabetic complications. [PDF]

Front Endocrinol (Lausanne)
Chen X, Huang L, Xiao Z, Liu L.
europepmc   +1 more source

The GmGT‐2F, a trihelix transcription factor, regulates seed oil content by directly activating GmAGAL transcription in soybean

Journal of Integrative Plant Biology, EarlyView.
In soybean, the trihelix transcription factor GmGT‐2F positively regulates the expression of the α‐galactosidase gene GmAGAL, thereby modulating seed oil content. The cyclophilin GmCYP2 interacts with GmGT‐2F and suppresses GmAGAL activation. Haplotype diversity analysis of GmGT‐2F, GmCYP2, and GmAGAL identified favorable haplotype combinations ...
Shuangzhe Li, Yifan Cui, Yang Liu, Mingliang Yang, Xiaoxia Wu, Qingshan Chen, Ying Zhao   +6 more
wiley   +1 more source

Hyaluronic acid degradation by Purpureocillium lilacinum: biochemical and transcriptomic insights. [PDF]

Appl Microbiol Biotechnol
Minguet-Lobato M, Fernández-Polo D, Cervantes FV, Plou FJ, Fernández-Lobato M.   +4 more
europepmc   +1 more source