Scientific Reports, 2017 Understanding the molecular mechanisms of bacterial antibiotic resistance will help prepare against further emergence of multi-drug resistant strains. MacQ is an enzyme responsible for the multi-drug resistance of Acidovorax sp. strain MR-S7.
Yoshiaki Yasutake +6 more
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Transmembrane and Antimicrobial Peptides. Hydrophobicity, Amphiphilicity and Propensity to Aggregation [PDF]
arXiv, 2013 Development of the new antimicrobial agents against antibiotic resistance pathogens is the nowadays challenge. Antimicrobial peptides (AMP) occur as important defence agents in many organisms and offer a viable alternative to conventional antibiotics.
arxiv
Removal of N‐acetyl groups from blocked peptides with acylpeptide hydrolase [PDF]
, 1991 T C Farries +3 more
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The role of the peptides in enzymes at the origin of live [PDF]
arXiv, 2017 The peptides in biosystems are homochiral polymers of L-amino acids, but razemisate slowly by an active isomerization kinetics. The chemical reactions in biosystems are, however, reversible and what racemisates the peptides at the water activity in the biosystems can ensure homochirality at a smaller activity.
arxiv
Identification of proteins that interact with mammalian peptide: N -glycanase and implicate this hydrolase in the proteasome-dependent pathway for protein degradation [PDF]
, 2001 Hangil Park +2 more
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Novel alternatives to antibiotics: bacteriophages, bacterial cell wall hydrolases, and antimicrobial peptides [PDF]
, 2007 Albert Parisien +4 more
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Screening and Identification of Novel Soluble Epoxide Hydrolase Inhibitors from Corn Gluten Peptides [PDF]
, 2022 Jiamin Dang +2 more
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PepDoRA: A Unified Peptide Language Model via Weight-Decomposed Low-Rank Adaptation [PDF]
arXivPeptide therapeutics, including macrocycles, peptide inhibitors, and bioactive linear peptides, play a crucial role in therapeutic development due to their unique physicochemical properties. However, predicting these properties remains challenging.
arxiv
Membrane localisation of a UDP-sugar hydrolase, inSalmonella, is by an uncleaved N-terminal signal peptide [PDF]
, 1993 Robert A. Jones +3 more
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Journal of Lipid Research, 2010 LDL particles that enter the arterial intima become exposed to proteolytic and lipolytic modifications. The extracellular hydrolases potentially involved in LDL modification include proteolytic enzymes, such as chymase, cathepsin S, and plasmin, and ...
Riia Plihtari +3 more
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