EPR Studies on the Mono- and Dicobalt(II)-Substituted Forms of the Aminopeptidase from \u3cem\u3eAeromonas proteolytica\u3c/em\u3e. Insight into the Catalytic Mechanism of Dinuclear Hydrolases [PDF]
, 1997 The structure and function of the prototypical dinuclear hydrolase, namely, the aminopeptidase from Aeromonas proteolytica (AAP), was probed by EPR spectroscopy of the mono- and dicobalt(II)-substituted derivatives.
Bennett, Brian, Holz, Richard C.
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P. aeruginosa CtpA protease adopts a novel activation mechanism to initiate the proteolytic process
The EMBO JournalDuring bacterial cell growth, hydrolases cleave peptide cross-links between strands of the peptidoglycan sacculus to allow new strand insertion.
Hao-Chi Hsu +4 more
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What’s the importance of peptidases in cancer? [PDF]
Einstein (São Paulo), 2009 A synonym for a successful tumor spread is a productive invasive cell migration, a process by which the extracellular matrix plays the role of substrate for cells to move and reach a secondary site.
Adriana Miti Nakahata +2 more
doaj
How shall we use the proteomics toolbox for biomarker discovery? [PDF]
, 2007 Biomarker discovery for clinical purposes is one of the major areas in which proteomics is used. However, despite considerable effort, the successes have been relatively scarce.
Hochstrasser, Denis +2 more
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Multi-omic Analyses of Extensively Decayed Pinus contorta Reveal Expression of a Diverse Array of Lignocellulose-Degrading Enzymes. [PDF]
, 2018 Fungi play a key role cycling nutrients in forest ecosystems, but the mechanisms remain uncertain. To clarify the enzymatic processes involved in wood decomposition, the metatranscriptomics and metaproteomics of extensively decayed lodgepole pine were ...
Barry, Kerrie +13 more
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Frontiers in Microbiology, 2019 The cell wall (CW) of bacteria is an intricate arrangement of macromolecules, at least constituted of peptidoglycan (PG) but also of (lipo)teichoic acids, various polysaccharides, polyglutamate and/or proteins. During bacterial growth and division, there
Aurore Vermassen +5 more
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A novel class of CoA-transferase involved in short-chain fatty acid metabolism in butyrate-producing human colonic bacteria [PDF]
, 2005 Peer reviewedPublisher ...
Altschul +48 more
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Unveiling a CAAX Protease‐Like Protein Involved in Didemnin Drug Maturation and Secretion
Advanced ScienceThe assembly line biosynthesis of the powerful anticancer‐antiviral didemnin cyclic peptides is proposed to follow a prodrug release mechanism in Tristella bacteria.
Xiaolin Zou +12 more
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Journal of Lipid Research, 2010 LDL particles that enter the arterial intima become exposed to proteolytic and lipolytic modifications. The extracellular hydrolases potentially involved in LDL modification include proteolytic enzymes, such as chymase, cathepsin S, and plasmin, and ...
Riia Plihtari +3 more
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Phage lytic proteins: Biotechnological applications beyond clinical antimicrobials [PDF]
, 2017 Most bacteriophages encode two types of cell wall lytic proteins: endolysins (lysins) and virion-associated peptidoglycan hydrolases. Both enzymes have the ability to degrade the peptidoglycan of Gram-positive bacteria resulting in cell lysis when they ...
Donovan, David M. +5 more
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