Results 101 to 110 of about 497,366 (249)

S. aureus colonization and clinical symptoms remain stable upon topical XZ.700 treatment: Results of a double‐blind randomized clinical trial in patients with mild to moderate atopic dermatitis

British Journal of Clinical Pharmacology, EarlyView.
Aim Recovering dysbiosis may improve atopic dermatitis (AD) symptoms. XZ.700 is a recombinant chimeric endolysin that specifically targets Staphylococcus aureus and could be a new treatment option for patients with AD. The aim of this first‐in‐human study was to evaluate the safety, tolerability and efficacy of topical XZ.700 and explore the ...
Laura W. J. van der Meulen, Menthe E. Bergmans, Salma Assil, Naomi Klarenbeek, Marieke L. de Kam, Alexa J. Tibboel, Thorsten Brach, Bjorn L. Herpers, Johan Frieling, Vincent de Jong, Benthe Freyee, Martijn B. A. van Doorn, Robert Rissmann, Tessa Niemeyer–van der Kolk   +13 more
wiley   +1 more source

Variability of expression of trypsyn peptide hydrolases in Drosophila virilis laboratory

, 2016
Проведено дослідження активності трипсиноподібних пептидгідролаз личинок, лялечок та імаго лабораторної популяції Drosophila virilis. Математично визначені кількісні показники активності ферменту: відносна та питома активність трипсиноподібних ...
Подзолкова, Юлія Юріївна
core   +1 more source

Viral Peptide Targeted Delivery of Nano-Therapeutics

, 2013
Over the past decade, an increasing number of potential drugs have been suggested for therapeutic applications. Often bio-macromolecules show a limited ability to cross the plasma membrane resulting in poor cellular access, which largely prevents them ...
GALDIERO, MASSIMILIANO, Massimiliano Galdiero, FALANGA, ANNARITA, PERILLO, EMILIANA, CANTISANI, MARCO, MORELLI, GIANCARLO, GALDIERO, STEFANIA   +6 more
core  

Peptide transport in Candida albicans and synthetic antifungal agents [PDF]

, 1986
These studies have characterized the peptide transport systems of Candida albicans, with a view to the rational design of peptide antifungal agents exploiting the 'smugglin' concept.
Shallow, David A.
core  

Virucidal Peptide-Based Drugs to Target Influenza [PDF]

SUNMI
Kordbacheh, Shadi, Olgiati, Francesca, Stellacci, Francesco   +2 more
core   +1 more source

Affinity Peptides With pH Sensitivity for the Enrichment of CD38+ Cells

Biotechnology and Bioengineering, EarlyView.
ABSTRACT The selective enrichment of cell populations based on surface markers is critical for the advancement of gene and cell therapies. Current antibody‐based cell isolation methods, such as fluorescence‐ and magnetic‐activated cell sorting (FACS and MACS), offer high specificity but are limited by scalability, cost, and potential adverse effects on
Gabrielle Rusch, Mickael Meyer, I. Mohamed Irfan, Carson Huber, Joseph Burclaff, Scott T. Magness, Stefano Menegatti, Michael Daniele   +7 more
wiley   +1 more source

Metallopeptidases of Toxoplasma gondii: in silico identification and gene expression

Parasite, 2018
Metallopeptidases are a family of proteins with domains that remain highly conserved throughout evolution. These hydrolases require divalent metal cation(s) to activate the water molecule in order to carry out their catalytic action on peptide bonds by ...
Escotte-Binet Sandie, Huguenin Antoine, Aubert Dominique, Martin Anne-Pascaline, Kaltenbach Matthieu, Florent Isabelle, Villena Isabelle   +6 more
doaj   +1 more source

Impact of Agitation Power Input on Aspergillus oryzae Metabolism: Application of Multi‐Omics on an Industrial Enzyme Fermentation

Biotechnology and Bioengineering, EarlyView.
ABSTRACT The agitation power input substantially impacts the oxygen transfer rate in aerobic fermentation processes. Furthermore, in a carbon‐limited process where the substrate feed rate is controlled by the concentration of dissolved oxygen, the power input will consequently govern the feed rate.
Mariana Albino, Jean‐Marie Mouillon, Gisela Nadal‐Rey, Carina L. Gargalo, Ulrich Krühne, Krist V. Gernaey, Mads O. Albæk   +6 more
wiley   +1 more source

Highly efficient discovery of the covalent Mpro inhibitors from crude Pu-erh tea by integrating biochemical and chemoproteomic approaches

Food Science and Human Wellness
The main proteases (Mpros) are hydrolases playing essential roles in the replication of β-coronaviruses including SARS-CoV-2. Herein, a highly efficient strategy was developed for discovering the Mpro inactivators from crude plant extract integrating ...
Guanghao Zhu, Yani Zhang, Shenglan Qi, Jianrong Xu, Yuan Xiong, Zhaoqin Zhang, Xixiang Chen, Yuanyuan Xie, Xiaoqing Guan, Weidong Zhang, Wei Liu, Guangbo Ge   +11 more
doaj   +1 more source

Peptide hydrolase activity of Klebsiella aerogenes [PDF]

Biochemical Journal, 1969
S. A. Barker, P. J. Somers, R. Epton
openaire   +2 more sources