Results 101 to 110 of about 572,875 (296)

Synthesis of Human Milk Oligosaccharides: Protein Engineering Strategies for Improved Enzymatic Transglycosylation

Molecules, 2019
Human milk oligosaccharides (HMOs) signify a unique group of oligosaccharides in breast milk, which is of major importance for infant health and development.
Birgitte Zeuner, David Teze, Jan Muschiol, Anne S. Meyer   +3 more
doaj   +1 more source

Peptide Hydrolase C in Germinating Barley [PDF]

Plant Physiology, 1970
W C, Burger, N, Prentice, M, Moeller
openaire   +2 more sources

Peptide hydrolase activity of Klebsiella aerogenes [PDF]

Biochemical Journal, 1969
S. A. Barker, P. J. Somers, R. Epton
openaire   +2 more sources

Regulation of plasminogen activator production by endothelial cells : Role in fibrinolysis and local proteolysis

, 1991
Chemicals/CAS: Peptide Hydrolases, EC 3.4; Tissue Plasminogen Activator, EC 3.4.21 ...
Kooistra, T., Koolwijk, P., Emeis, J.J., Hinsbergh, V.W.M. van   +3 more
core  

Biocatalysts for Peptide Geranylation With Linear and Cyclic Prenyl Groups

Angewandte Chemie International Edition, EarlyView.
A combination of genome mining, synthetic biology, and biocatalytic assays revealed enzymes that install linear and cyclized prenyl moieties on ribosomally or chemically synthesized peptides. The promiscuity of both enzymes, while being specific for modification of C‐terminal tryptophans, enables enzymatic access to peptide terpenoid hybrids.
Sarolt Magyari, Leon F. Schwarz, Luca Schlautmann, Kai Schließmann, Christopher Slotman, Nina von Felten, Claus‐Michael Lehr, Rolf Müller, Alexander F. Kiefer, Jörn Piel, Florian Hubrich   +10 more
wiley   +1 more source

Metallopeptidases of Toxoplasma gondii: in silico identification and gene expression

Parasite, 2018
Metallopeptidases are a family of proteins with domains that remain highly conserved throughout evolution. These hydrolases require divalent metal cation(s) to activate the water molecule in order to carry out their catalytic action on peptide bonds by ...
Escotte-Binet Sandie, Huguenin Antoine, Aubert Dominique, Martin Anne-Pascaline, Kaltenbach Matthieu, Florent Isabelle, Villena Isabelle   +6 more
doaj   +1 more source

Statistical deconvolution of enthalpic energetic contributions to MHC-peptide binding affinity [PDF]

, 2006
Background: MHC Class I molecules present antigenic peptides to cytotoxic T cells, which forms an integral part of the adaptive immune response. Peptides are bound within a groove formed by the MHC heavy chain. Previous approaches to MHC Class I-peptide
Hattotuwagama, C.K., Moss, David S., Davies, M.N., David S Moss, Drew, M.G.B., Channa K Hattotuwagama, Drew, Michael G.B., Flower, Darren R., Matthew N Davies, Hattotuwagama, Channa K., Davies, Matthew N., Michael GB Drew, Darren R Flower, Flower, D.R., Moss, D.S.   +14 more
core   +1 more source

Modulation of Animal Gut Health by Milk Oligosaccharide

Animal Research and One Health, EarlyView.
This review summarizes the composition and structural characteristics of MOs across different mammalian species, and elucidates their roles and mechanisms in maintaining intestinal homeostasis by regulating gut microbiome and enhancing intestinal chemical, physical and immune barriers.
Ningtao Chen, Nana Jing, Shiyu Tao, Mingyue Fei, Wentao Lv, Hua Yang, Yingping Xiao, Haiqin Wu   +7 more
wiley   +1 more source

Highly efficient discovery of the covalent Mpro inhibitors from crude Pu-erh tea by integrating biochemical and chemoproteomic approaches

Food Science and Human Wellness
The main proteases (Mpros) are hydrolases playing essential roles in the replication of β-coronaviruses including SARS-CoV-2. Herein, a highly efficient strategy was developed for discovering the Mpro inactivators from crude plant extract integrating ...
Guanghao Zhu, Yani Zhang, Shenglan Qi, Jianrong Xu, Yuan Xiong, Zhaoqin Zhang, Xixiang Chen, Yuanyuan Xie, Xiaoqing Guan, Weidong Zhang, Wei Liu, Guangbo Ge   +11 more
doaj   +1 more source

Conjugating Catalytic Polyproline Fragments with a Self-Assembling Peptide Produces Efficient Artificial Hydrolases

, 2020
A polyproline fragment containing a catalytic dyad of His–His or Ser–His was coupled with a self-assembling peptide MAX1 to design new hydrolases (H2H5 and H2S5) for catalyzing ester hydrolysis. Circular dichroism measurements indicated that the peptides
Chi-Ching Yu, Jia-Cherng Horng, Jia-Cherng Horng (1424146), Kuei-Yen Huang (1512328), Chi-Ching Yu (4419145), Kuei-Yen Huang   +5 more
core   +1 more source