Results 81 to 90 of about 40,308 (299)

Peptide hydrolases in senescing ragi leaves

Biologia Plantarum, 1987
Two peptide hydrolases — one active at pH 7.0 and the other at pH 3.4 (SH-dependent) were detected in ragi (Eleusine coracana Gaertn. cv. PR 202) leaves. The absolute activities of both acid and neutral peptide hydrolases were move or less stable in attached leaves and exhibited a mild rise in excised leaves, whereas the specific activities exhibited a
K. B. Kumar, G. B. Mohanty, S. Patnaik, A. Bhuyan, P. A. Khan   +4 more
openaire   +1 more source

What’s the importance of peptidases in cancer? [PDF]

Einstein (São Paulo), 2009
A synonym for a successful tumor spread is a productive invasive cell migration, a process by which the extracellular matrix plays the role of substrate for cells to move and reach a secondary site.
Adriana Miti Nakahata, Maria Luiza Vilela Oliva, Oswaldo Keith Okamoto   +2 more
doaj  

P. aeruginosa CtpA protease adopts a novel activation mechanism to initiate the proteolytic process

The EMBO Journal
During bacterial cell growth, hydrolases cleave peptide cross-links between strands of the peptidoglycan sacculus to allow new strand insertion.
Hao-Chi Hsu, Michelle Wang, Amanda Kovach, Andrew J Darwin, Huilin Li   +4 more
doaj   +1 more source

Distribution des protéines et des activités des hydrolases peptidiques dans les parties aériennes de blé d’hiver cultivé en champ durant la saison froide [PDF]

, 1993
Winter cereals in the field are subject to low temperatures during an early stage of vegetative growth. Metabolic activities are low during this period. The quantities of enzymes involved in nitrogen assimilation, carbon assimilation and photorespiration
A. Fischer, Fischer, Andreas, U. Feller, Feller, Urs   +3 more
core   +1 more source

Cell Wall Hydrolases in Bacteria: Insight on the Diversity of Cell Wall Amidases, Glycosidases and Peptidases Toward Peptidoglycan

Frontiers in Microbiology, 2019
The cell wall (CW) of bacteria is an intricate arrangement of macromolecules, at least constituted of peptidoglycan (PG) but also of (lipo)teichoic acids, various polysaccharides, polyglutamate and/or proteins. During bacterial growth and division, there
Aurore Vermassen, Sabine Leroy, Régine Talon, Christian Provot, Magdalena Popowska, Mickaël Desvaux   +5 more
doaj   +1 more source

In Silico to In Cerebro—Development of the Orexin Receptor Antagonist “Photorexant” for Photomodulation In Vitro and in Mouse Brains

Angewandte Chemie International Edition, EarlyView.
Following a structure‐based design approach, photoswitchable derivatives of the FDA‐approved drug suvorexant were designed, docked, synthesized, and characterized pharmacologically at the orexin 1 and 2 receptors (OX1R and OX2R). Optimized “photorexant” showed up to an 11‐fold difference in IC50 between photoisomers, enabled dynamic and reversible ...
Marcus Angermann, Marie H. Deventer, Vicente Ledesma‐Martin, Nuno Martinho, Alix Flake, Silvia Mori, Angel Nuñez, Jaime Pignatelli, Rita C. Guedes, Christophe P. Stove, Michael Decker   +10 more
wiley   +1 more source

The study of a new and specific proline cleaving peptidase from bovine serum [PDF]

, 2003
Prolyl oligopeptidase is a serine peptidase characterised by oligoendopeptidase activity. Definitive evidence for the discrete biological role of prolyl oligopeptidase remains unknown, though its role in the maturation and degradation of peptide hormones
Collins, Patrick
core  

The Phanerochaete chrysosporium secretome : database predictions and initial mass spectrometry peptide identifications in cellulose-grown medium [PDF]

, 2005
The white rot basidiomycete, Phanerochaete chrysosporium, employs an array of extracellular enzymes to completely degrade the major polymers of wood: cellulose, hemicellulose and lignin.
Teeri, Tuula T.,, Gaskell, Jill, Kersten, Philip J., Vanden Wymelenberg, Amber, Martinez, Diego, Rajangam, Alex S.,, Sabat, Grzegorz, Cullen, Dan   +7 more
core   +1 more source

Enzimas proteolíticas relacionadas con la enfermedad periodontal inflamatoria

Revista Cubana de Estomatología, 1998
La enfermedad periodontal inflamatoria ocasiona la destrucción de los tejidos que protegen y soportan al diente; es por eso de gran importancia el papel que pueden desempeñar las enzimas que sean capaces de degradar la matriz del tejido conectivo, como ...
Bárbara E. García Triana, Agustín Vicedo Tomey,, José C García Piñeiro, Alberto Saldaña Bernabeu   +3 more
doaj  

Unveiling a CAAX Protease‐Like Protein Involved in Didemnin Drug Maturation and Secretion

Advanced Science
The assembly line biosynthesis of the powerful anticancer‐antiviral didemnin cyclic peptides is proposed to follow a prodrug release mechanism in Tristella bacteria.
Xiaolin Zou, Zhen Hui, Robert A. Shepherd, Shuaiqiang Zhao, Yanfei Wu, Zhuanglin Shen, Cuiping Pang, Shipeng Zhou, Zehai Yu, Jiahai Zhou, Bradley S. Moore, Laura M. Sanchez, Xiaoyu Tang   +12 more
doaj   +1 more source