Results 41 to 50 of about 6,263,550 (261)

Discovery of Surfactant-Like Peptides from a Phage-Displayed Peptide Library

open access: yesViruses, 2020
Peptides with specific affinities for various materials have been identified in the past three decades and utilized in materials science and engineering. A peptide’s capability to specifically interact with materials is not naturally derived but screened
Toshiki Sawada   +3 more
doaj   +1 more source

Peptide-based hydrogel for enhanced bone repair

open access: yesMaterials & Design, 2023
Peptide-based hydrogels are widely studied and applied in bone repair because of their good biocompatibility, biodegradability and designability. Peptide-based hydrogels can be endowed with different properties by introducing biologically functional ...
Yi Fan   +9 more
doaj   +1 more source

Salmonella lipopolysaccharide‐containing supported lipid bilayers as platforms to study bacteriophage interactions

open access: yesFEBS Letters, EarlyView.
We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace   +6 more
wiley   +1 more source

Esculentin 1-21: a linear antimicrobial peptide from frog skin with inhibitory effect on bovine mastitis-causing bacteria

open access: yes, 2009
Mastitis, or inflammation of the mammary gland, is the most common and expensive illness of dairy cows throughout the world. Although stress and physical injuries may give rise to inflammation of the udders, infections by bacteria or other microorganisms
Islas-Rodriguez, A.E.   +20 more
core   +1 more source

ABL kinase‐dependent phosphorylation of SH proteins promotes their direct interaction with CRK family SH2 domains

open access: yesFEBS Letters, EarlyView.
CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens   +8 more
wiley   +1 more source

β-Hairpin-Based Peptide Hydrogels: The Case of MAX1

open access: yesGels
This review explores the advancements and applications of β-hairpin peptide hydrogels, starting from the paradigmatic case of MAX1 and its highly versatile analogue MAX8.
Mariantonietta Pizzella   +6 more
doaj   +1 more source

Piezoelectric Peptide and Metabolite Materials

open access: yesResearch, 2019
Piezoelectric materials are important for many physical and electronic devices. Although many piezoelectric ceramics exhibit good piezoelectricity, they often show poor compatibility with biological systems that limits their biomedical applications ...
Hui Yuan   +5 more
doaj   +1 more source

Reconstructing enzyme evolution by protein engineering

open access: yesFEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler   +2 more
wiley   +1 more source

Adaptively evolved human oral actinomyces‐sourced defensins show therapeutic potential

open access: yesEMBO Molecular Medicine, 2021
The development of eukaryote‐derived antimicrobial peptides as systemically administered drugs has proven a challenging task. Here, we report the first human oral actinomyces‐sourced defensin—actinomycesin—that shows promise for systemic therapy ...
Shunyi Zhu   +6 more
doaj   +1 more source

Exploiting Peptide Self-Assembly for the Development of Minimalistic Viral Mimetics

open access: yesFrontiers in Chemistry, 2021
Viruses are natural supramolecular nanostructures that form spontaneously by molecular self-assembly of complex biomolecules. Peptide self-assembly is a versatile tool that allows mimicking viruses by creating their simplified versions through the design
Patrizia Janković   +4 more
doaj   +1 more source

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