Results 31 to 40 of about 840,168 (263)

Peptide-based materials for cancer immunotherapy [PDF]

Theranostics, 2019
Peptide-based materials hold great promise as immunotherapeutic agents for the treatment of many malignant cancers. Extensive studies have focused on the development of peptide-based cancer vaccines and delivery systems by mimicking the functional domains of proteins with highly specific immuno-regulatory functions or tumor cells fate controls. However,
Zhang, Lu, Huang, Yanyu, Lindstrom, Aaron Raymond, Lin, Tzu-Yin, Lam, Kit S, Li, Yuanpei   +5 more
openaire   +3 more sources

Peptide-Based Nanogels for Pharmaceutical and Biotechnological Applications: From Fmoc-FF to Other Peptide Sequences

Pharmaceuticals
Peptide-based materials represent a rapidly growing field in nanotechnology, bridging bottom-up self-assembly and top-down approaches for the development of functional nanostructures.
Mariangela Rosa, Sabrina Marino, Giancarlo Morelli, Antonella Accardo, Carlo Diaferia   +4 more
doaj   +1 more source

Antimicrobial peptide-inspired antibacterial polymeric materials for biosafety

Biosafety and Health, 2022
The emergence of antimicrobial resistance attributed to the overuse and abuse of antibiotics severely endangers global biosafety. Antimicrobial peptides (AMPs) produced by various living organisms exhibit broad-spectrum antimicrobial properties with a ...
Min Lin, Jing Sun
doaj   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

FEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe, Tanmay Kumar Mohanty, Rashna Bhandari, Dorothea Fiedler   +3 more
wiley   +1 more source

Formation mechanisms of chitosan-silica hybrid materials and its performance as solid support for KR-12 peptide adsorption: Impact on KR-12 antimicrobial activity and proteolytic stability

Journal of Materials Research and Technology, 2020
Chitosan-silica materials offer a specific environment for the adsorption of biofunctional molecules, such as the antimicrobial peptide KR-12. The objective here is to rationalize the changes in the physicochemical properties of these chitosan-silica ...
Johnatan Diosa, Fanny Guzman, Claudia Bernal, Monica Mesa   +3 more
doaj   +1 more source

Self-assembling, pH-responsive nanoflowers for inhibiting PAD4 and neutrophil extracellular trap formation and improving the tumor immune microenvironment

Acta Pharmaceutica Sinica B, 2022
Self-assembling carrier-free nanodrugs are attractive agents because they accumulate at tumor by an enhanced permeability and retention (EPR) effect without introduction of inactive substances, and some nanodrugs can alter the immune environment.
Di Zhu, Yu Lu, Lin Gui, Wenjing Wang, Xi Hu, Su Chen, Yanming Wang, Yuji Wang   +7 more
doaj   +1 more source

The planar cell polarity protein Vangl2 interacts with the PDZ‐domains of Scribble but not with a unique PDZ‐like domain in Inturned

FEBS Letters, EarlyView.
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes, Jan Brysch, Carmen Gelze, Lilli Meier, Daniel Kümmel   +4 more
wiley   +1 more source

Discovery of Surfactant-Like Peptides from a Phage-Displayed Peptide Library

Viruses, 2020
Peptides with specific affinities for various materials have been identified in the past three decades and utilized in materials science and engineering. A peptide’s capability to specifically interact with materials is not naturally derived but screened
Toshiki Sawada, Rina Oyama, Michihiro Tanaka, Takeshi Serizawa   +3 more
doaj   +1 more source

Advances and Perspectives of Peptide and Polypeptide‐Based Materials for Biomedical Imaging

Advanced NanoBiomed Research, 2021
Biomedical imaging is an effective tool to reveal internal structures beneath the skin. Such tools are of great importance for disease diagnosis and treatment.
Mingchen Lv, Erik Jan Cornel, Zhen Fan, Jianzhong Du   +3 more
doaj   +1 more source

Peptide-based hydrogel for enhanced bone repair

Materials & Design, 2023
Peptide-based hydrogels are widely studied and applied in bone repair because of their good biocompatibility, biodegradability and designability. Peptide-based hydrogels can be endowed with different properties by introducing biologically functional ...
Yi Fan, Guangkai Ren, Yutao Cui, He Liu, Shaorong Li, Yuhang Tian, Gan Wang, Chuangang Peng, Yanbing Wang, Dankai Wu   +9 more
doaj   +1 more source