Results 181 to 190 of about 200,834 (306)

Identification of Escherichia coli, Klebsiella pneumoniae, and Pseudomonas aeruginosa in Blood Cultures: a Multicenter Performance Evaluation of a Three-Color Peptide Nucleic Acid Fluorescence In Situ Hybridization Assay

, 2011
Phyllis Della‐Latta, Hossein Salimnia, Theresa Painter, Fann Wu, Gary W. Procop, Donald A. Wilson, Wendy Gillespie, Alayna Mender, Benjamin Crystal   +8 more
openalex   +2 more sources

Peptide Nucleic Acid (PNA) Antisense Effects inEscherichia coli [PDF]

, 1999
Liam Good, Peter Nielsen
openalex   +1 more source

RPS3‐Enriched Extracellular Vesicles Mediate Liver‐Spinal Cord Inter‐Organ Communication

Advanced Science, EarlyView.
Spinal cord injury activates the liver to send extracellular vesicles loaded with RPS3 protein to the lesion site. These vesicles are taken up by neural stem cells and astrocytes, triggering NF‐κB signaling, impairing the regeneration of neurons and myelin, and promotes harmful inflammation, ultimately hindering recovery.
Peiwen Song, Zuomeng Wu, Yixiang Dong, Yunxiong Fang, Shiyu Bian, Daokuan Wang, Huang Fang, Yunlei Liu, Wang Ying, Jun Qian, Tianyu Han, Cailiang Shen   +11 more
wiley   +1 more source

An antisense peptide-conjugated peptide nucleic acid (PPNA) for peptidoglycan recycling inhibition reduces AmpC hyperproduction and β-lactam resistance in <i>Pseudomonas aeruginosa</i>. [PDF]

Microbiol Spectr
Escobar-Salom M, Barceló IM, Sansó-Sastre J, Torrens G, Jordana-Lluch E, Moyà B, Oliver A, Juan C.   +7 more
europepmc   +1 more source

OCTN2 Activates a Non‐Canonical Carnitine Metabolic Pathway to Promote MASH‐HCC Progression and Immunotherapy Resistance

Advanced Science, EarlyView.
In non‐MASH‐HCC, L‐carnitine promotes tumor progression primarily through its classical role in enhancing fatty acid oxidation (FAO). However, in MASH‐HCC, where FAO is markedly suppressed, L‐carnitine shifts from this canonical function to serve instead as an intracellular acetyl group buffer.
Chuqi Xia, Xiao Zhang, Jinze Li, Ning Xu, Sheng Hu, Qiyu Lu, Yuxuan Li, Taifu Xiao, Xu Li, Xue Wang, Kequan Xu, Daoming Liang   +11 more
wiley   +1 more source

Revealing the Potential of a Chimaera: a Peptide-Peptide Nucleic Acid Molecule Designed To Interact with the SARS-CoV-2 Nucleocapsid Protein. [PDF]

Angew Chem Int Ed Engl
Tino AS, Quagliata M, Schiavina M, Pacini L, Papini AM, Felli IC, Pierattelli R.   +6 more
europepmc   +1 more source

Rapid extraction-free detection of the R132H isocitrate dehydrogenase mutation in glioma using colorimetric peptide nucleic acid-loop mediated isothermal amplification (CPNA-LAMP). [PDF]

PLoS One, 2023
Choate KA, Raack EJ, Line VF, Jennings MJ, Belton RJ, Winn RJ, Mann PB.   +6 more
europepmc   +1 more source

Optimization of peptide nucleic acid (PNA) oligomer synthesis using Fmoc/acyl-protected monomers

, 2000
Györgyi Kovács, Zoltán Tímár, Zoltán Kele, Lajos Kovács   +3 more
openalex   +1 more source

Non‐Targeting shRNA‐Encoded Plasmid DNA Enhances Protective Immunity Through RIDD‐RIG‐I Signaling Pathway in the Zika Virus Animal Model

Advanced Science, EarlyView.
We present a novel DNA vaccine platform featuring intrinsic, non‐targeting dsRNA that significantly enhances immune responses by activating the regulated IRE1‐dependent decay‐RIG‐I signaling pathway. This research elucidates a previously uncharacterized mechanism for dsRNA‐mediated innate immune activation.
Min‐Syuan Huang, Hung‐Chun Liao, Po Peng, Wan‐Ling Wu, Kit Man Chai, Mei‐Yu Chen, Guann‐Yi Yu, Tsung‐Hsien Chuang, Hsin‐Wei Chen, Chuang‐Rung Chang, Shih‐Jen Liu   +10 more
wiley   +1 more source

De Novo Potent Peptide Nucleic Acid Antisense Oligomer Inhibitors Targeting SARS-CoV-2 RNA-Dependent RNA Polymerase via Structure-Guided Drug Design. [PDF]

Int J Mol Sci, 2023
Shehzadi K, Yu M, Liang J.
europepmc   +1 more source