Results 171 to 180 of about 3,183,923 (247)

Modeling Peptide Nucleic Acid Binding Enthalpies Using MM-GBSA. [PDF]

J Phys Chem B, 2022
Goodman J, Attwood D, Kiely J, Coladas Mato P, Luxton R.   +4 more
europepmc   +1 more source

TP53 Loss Elevates NF‐κB‐IFN‐β‐MHC‐Ia Signaling to Promote NK Cell Resistance in Osteosarcoma

Advanced Science, EarlyView.
TP53 loss in a transforming or osteosarcoma cell promotes cytosolic DNA accumulation, activating NF‐κB‐dependent IFN‐β production. Autocrine IFN‐β signaling increases cell‐surface HLA‐Ia expression, strengthens inhibitory KIR signaling in natural killer cells, and thereby enables the affected cell to evade NK cell‐mediated cytotoxicity.
Guihui Qin, Cheung Kwan Yeung, Ye Yi, Dejin Zheng, Miaoman Ye, Chi‐Chong Chio, Jinjie Wu, Siyi Fu, Chu‐Xia Deng, Ren‐He Xu   +9 more
wiley   +1 more source

Recent Cutting-Edge Technologies for the Delivery of Peptide Nucleic Acid. [PDF]

Chemistry
Avitabile C, Cerasa MT, D'Aniello A, Saviano M, Moccia M.   +4 more
europepmc   +1 more source

Beyond Probiotics: Postbiotics for Healthy Aquaculture

Advanced Science, EarlyView.
This critical review assesses limitations of probiotics and proposes postbiotics, preparations of inanimate microorganisms and their metabolites, as a more stable, controlled, and biosafe formulation. Postbiotics offer significant advantages during industrial aquafeed production and storage. However, their practical implementation is currently hindered
Michael Leonidas Chikindas, Delin Xu, Igor V. Popov, Kayque Ordonho Carneiro, Nilufar Arashovna Elova, Gullola Amirovna Bekmurodova, Dildora Amindjanovna Amirsaidova, Astghik Pepoyan, Shakhlo Mirjamalovna Miralimova, Oleg V. Mitrokhin, Liubov S. Sichel, John Tagg, Svetoslav Dimitrov Todorov   +12 more
wiley   +1 more source

Evaluation of Peptide Nucleic Acid Encapsulation in Ferritin Nanocages for Gene Silencing Applications. [PDF]

Biomacromolecules
Falanga AP, Farina MV, Cianfoni G, Barolo L, Di Meo C, Borsatti GE, Ghirga F, Botta B, Pisano L, Borbone N, D'Errico S, Paone A, Oliviero G, Quaglio D, Baiocco P.   +14 more
europepmc   +1 more source

Nuclear IDH3A Drives Transcriptional Programs in Melanoma via the YBX1–JUN/FOS Axis

Advanced Science, EarlyView.
Genomic amplification drives aberrant nuclear localization of IDH3A in melanoma. Independent of its canonical metabolic activity, nuclear IDH3A cooperates with YBX1 to activate the c‐JUN/c‐FOS transcriptional program, while NONO facilitates its nuclear localization.
Juan Ran, Yanchun Fang, Shengming Ruan, Juling Wang, Songbai Liu, Yuan Mao, Dongsheng Hou, Yanping Wang, Zi Ye, Qiong Li, Daoxiang Zhang   +10 more
wiley   +1 more source

Peptide nucleic acid (PNA) clamps enhance root microbiome profiling in wheat and maize. [PDF]

Environ Microbiome
Mukhtar H, Easterly AC, Bachle KB, Ozorio D, Creech CF, Schachtman DP.   +5 more
europepmc   +1 more source

Forced Intercalation Peptide Nucleic Acid Probes for the Detection of an Adenosine-to-Inosine Modification. [PDF]

ACS Omega, 2023
Swenson CS, Argueta-Gonzalez HS, Sterling SA, Robichaux R, Knutson SD, Heemstra JM.   +5 more
europepmc   +1 more source

Advances in Aptamer Drug Delivery Systems for Treatment of Glioblastoma

Advanced Science, EarlyView.
Aptamers have remarkable recognition capacity which is suitable for assisting drug delivery for GB. This review demonstrates that aptamers have great potential as targeted therapeutic carriers, conjugated to various therapeutic carriers, using a range of conjugation strategies and chemistries.
Alexandra R. Paul, Alexandra Moreno Mitchell, Dean O'Neil, Yutong Luo, Khuloud T. Al‐Jamal   +4 more
wiley   +1 more source

A peptide nucleic acid-based pretargeting approach using ¹⁶¹Tb for radionuclide therapy in a murine tumor model. [PDF]

EJNMMI Res
Li H, Xiang X, Guan L, Wang J, Feng Y, Xia Z, Li W, Li J, Pang H, Wang Z.   +9 more
europepmc   +1 more source