Results 151 to 160 of about 3,183,923 (247)

Detection of a Target Nucleic Acid by Ligation-Assisted Fluorescence Enhancement of a Peptide Nucleic Acid (PNA) Twin Probe via Disulfide Binding. [PDF]

Biopolymers
Ouchi Y, Ishii K, Sato Y, Imai Y, Matsui H, Ohtsuki T, Hakata Y, Shigeto H, Yamamura S, Kitamatsu M.   +9 more
europepmc   +1 more source

Fluorescent nucleic acid systems for probing the G-quadruplex-forming sequences

, 2014
1
김병현, 김기태
core  

Nrsn1–Smarcc1 Coupling Regulates Neural Stem Cell Differentiation and Chronic‐phase Recovery After Ischemic Stroke

Advanced Science, EarlyView.
In the post‐stroke brain, Foxa2 induces the transcriptional upregulation of Nrsn1 in NSCs. Nrsn1 functionally couples with Smarcc1, modulating its nuclear availability and protein abundance, thereby influencing Smarcc1‐associated regulatory programs linked to neuronal lineage commitment. Through this coupling, Nrsn1 promotes the differentiation of NSCs
Ruolin Zhang, Chang Liu, Yuneng Zhou, Kaichen Zhao, Muyang Li, Bingcheng Cai, Ying Wang, Zhiyuan Yuan, Zhaoxin Liu, Zilong Yuan, Yao Xiao, Peiyang Zhou, Ke Shui, Wendai Bao, Min Zhang, Jun Qin, Jun Chen, Xin Yang, Zhiqiang Dong   +18 more
wiley   +1 more source

Advances in peptide nucleic acid for targeting RNA and genomic DNA. [PDF]

Cell Rep Phys Sci
De A, Kumar V, Saltzman WM, Slack FJ, Vikram A, Gupta A, Bahal R.   +6 more
europepmc   +1 more source

Cooperative strand displacement by peptide nucleic acid (PNA)

, 1998
Peptide nucleic acid, DNA targeting, sequence discrimination, anti ...
Nielsen, Peter Eigil, Larsen, H. Jakob, Kurakin, A.   +2 more
core  

Ribonucleotides Amplify Mitochondrial DNA‐Driven cGAS–STING Activation via FdUMP‐ribonucleotide Hybrid Particles to Potentiate Chemoimmunotherapy

Advanced Science, EarlyView.
This work develops a metabolic sharing strategy that employs cytidine monophosphate (CMP) to competitively reprogram floxuridine (FUDR) pyrimidine metabolism in colorectal tumor cells. Elevated intracellular FdUMP induces nucleotide imbalance, drives mitochondrial DNA release and cGAS‐STING innate immune cascade activation, and potentiates robust ...
Chao Wang, Chenxuan Zhao, Yesong Yao, Zhiwen Zou, Anxin Shi, Zhuo Feng, Mingkang Yang, Yue Yu, Yang Liu, Xuehui Rui, Jinhui Wu   +10 more
wiley   +1 more source

A Programmable Toolbox for Fragment-Specific DNA Labeling by Coupling a Chimeric γ‑Peptide Nucleic Acid-Peptide Invasion Probe with T7 Endonuclease I. [PDF]

JACS Au
Mao D, Aman R, Hasan E, Alsulaiman D.
europepmc   +1 more source

Self‐Assembling Peptide‐Adjuvant Conjugate (SaPAC) Platform for Precision Cancer Immunotherapy

Advanced Science, EarlyView.
A self‐assembling peptide–adjuvant conjugate links neoantigens to TLR7 agonism, forming cationic nanoparticles that enhance lymph‐node retention, dendritic‐cell activation, and antitumor T‐cell immunity. This chemically defined platform shows how synchronized antigen and innate stimulation can be adapted across melanoma, bladder cancer, and triple ...
Yang‐Fan Wu, Jing‐Chu Hu, Ye‐Fan Hu, Wen‐Jun Li, Li Rong, Ren‐Hao Li, Yuan Yao, Lehan Hu, Xiao‐Lei Wang, Bao‐Zhong Zhang, Yicheng Lu, Shing‐Fung Chow, Canhui Su, Thomas Yau, Clive Yik‐Sham Chung, Jian‐Dong Huang   +15 more
wiley   +1 more source

Modulating backbone flexibility in hydroxamate siderophores for improved iron chelation and peptide nucleic acid delivery into bacteria. [PDF]

Biochem J
Tsylents U, Maj P, Wdowiak M, Stadnicki J, Mieczkowski A, Wojciechowska M, Trylska J.   +6 more
europepmc   +1 more source

DNA recognition and induced genome modification by a hydroxymethyl-γ tail-clamp peptide nucleic acid. [PDF]

Cell Rep Phys Sci, 2023
Oyaghire SN, Quijano E, Perera JDR, Mandl HK, Saltzman WM, Bahal R, Glazer PM.   +6 more
europepmc   +1 more source