Results 191 to 200 of about 765,071 (332)

Onion‐Mitochondria Inhibit Lipopolysaccharide‐Induced Acute Lung Injury by Shaping Lung Macrophage Mitochondrial Function

Advanced Science, EarlyView.
Proposed model of orally administered onion mitochondria (O‐Mit) uptake by lung macrophages and fuse with macrophage mitochondria (M‐Mit). This fusion reprograms the metabolism of dysfunctional M‐Mit in lipopolysaccharide‐induced murine acute lung injury by modulating dynamin‐related protein 1 (DRP1) phosphorylation and cardiolipin peroxidation ...
Qingbo Xu, Yun Teng, Yinan Huang, Jingyao Mu, Lucy Teng, Hongjia Qian, Qiming Huang, Minmin Liu, Yi Zou, Lifeng Zhang, Michael L Merchant, Xiang Zhang, Jun Yan, Huang‐Ge Zhang   +13 more
wiley   +1 more source

Forced Intercalation Peptide Nucleic Acid Probes for the Detection of an Adenosine-to-Inosine Modification. [PDF]

ACS Omega, 2023
Swenson CS, Argueta-Gonzalez HS, Sterling SA, Robichaux R, Knutson SD, Heemstra JM.   +5 more
europepmc   +1 more source

Adjusting the Structure of a Peptide Nucleic Acid (PNA) Molecular Beacon and Promoting Its DNA Detection by a Hybrid with Quencher-Modified DNA [PDF]

, 2022
Hajime Shigeto, Takamasa Kishi, Koki Ishii, Takashi Ohtsuki, Shohei Yamamura, Mizuki Kitamatsu   +5 more
openalex   +1 more source

Tetrahedral DNA Nanoparticle Vector for Intracellular Delivery of Targeted Peptide Nucleic Acid Antisense Agents to Restore Antibiotic Sensitivity in Cefotaxime-Resistant Escherichia coli

Nucleic Acid Therapeutics, 2017
J. Readman, G. Dickson, N. Coldham
semanticscholar   +1 more source

Multi‐Habitat Landscape Promotes Microbial Diversity: Insights from the Traditional Agricultural Heritage and the Global Trend

Advanced Science, EarlyView.
The 2500‐year‐old Mulberry‐dyke and Fish‐pond agricultural heritage system reveals how interconnected habitats foster microbial diversity. Multi‐habitat landscapes enhance microbial diversity through cross‐habitat dispersal and adaptive trait convergence. Globally, regions with diverse habitats support a greater diversity of soil microbiomes.
Jintao He, Jian Xiao, Xiaoqiang Shen, Kankan Zhao, Xiaoyu Lei, Huarui Zhang, Chao Sun, Huijie Lu, Yongqi Shao   +8 more
wiley   +1 more source

Targeting a KRAS i-motif forming sequence by unmodified and gamma-modified peptide nucleic acid oligomers. [PDF]

Biopolymers, 2023
Sarkar S, Colón-Roura G, Pearse A, Armitage BA.   +3 more
europepmc   +1 more source

A Viral RNA Silencing Suppressor Modulates Reactive Oxygen Species Levels to Induce the Autophagic Degradation of Dicer‐Like and Argonaute‐Like Proteins

Advanced Science, EarlyView.
Understanding the virus‐host arms race has been a fascinating topic in virology; contributing significantly to the development of treatments and control strategies for viral diseases. CHV1 employs a sophisticated counter‐defense mechanism in its fungal host by utilizing a viral silencing suppressor to inhibit fungal FMN reductase; thereby modulating ...
Shiyu Zhai, Tianxing Pang, Shiyu Peng, Shenshen Zou, Zhiping Deng, Nobuhiro Suzuki, Zhensheng Kang, Ida Bagus Andika, Liying Sun   +8 more
wiley   +1 more source

Peptide Nucleic Acids as Tools for Single-Molecule Sequence Detection and Manipulation

, 2011
Hagar Zohar, Craig L. Hetherington, Carlos Bustamante, Susan J. Muller   +3 more
openalex   +2 more sources

Nociceptive Nerve‐Derived CGRP Exacerbates Uterine Fibrogenesis in Adenomyosis by Promoting CD140b+ CD146+ Fibroblast Differentiation

Advanced Science, EarlyView.
This study investigates adenomyosis fibrosis in relation to nociceptive nerves. Nociceptive nerve‐secreted CGRP promotes RAMP1hi CD140b+ CD146+ fibroblast differentiation into myofibroblasts through ERK activation, causing severe fibrosis. Rimegepant‐induced CGRP/RAMP1 signaling blockade alleviates fibrosis and restores fertility in a mouse model. This
Zi Ye, Anning Zhao, Xia Li, Yanqing Hao, Dong Huang, Jianmin Chen, Tiantian Li, Yangyang Dai, Wenchao Sun, Lie Ma, Songying Zhang, Liaobing Xin   +11 more
wiley   +1 more source

Isoorotamide-based peptide nucleic acid nucleobases with extended linkers aimed at distal base recognition of adenosine in double helical RNA. [PDF]

Beilstein J Org Chem
Walby GD, Tessier BR, Mabee TL, Hoke JM, Bleam HM, Giglio-Tos A, Harding EE, Baskevics V, Katkevics M, Rozners E, MacKay JA.   +10 more
europepmc   +1 more source