Results 221 to 230 of about 686,761 (347)

Brain delivery of small interfering ribonucleic acid and drugs through intranasal administration with nano-sized polymer micelles

Medical Devices: Evidence and Research, 2015
Takanori Kanazawa School of Pharmacy, Tokyo University of Pharmacy and Life Sciences, Tokyo, Japan Abstract: Recently, the development of effective strategies for enhancing drug delivery to the brain has been a topic of great interest in both clinical ...
Kanazawa T
doaj  

Development of a Novel Peptide Nucleic Acid Probe for the Detection of Legionella spp. in Water Samples. [PDF]

Microorganisms, 2022
Nácher-Vázquez M, Barbosa A, Armelim I, Azevedo AS, Almeida GN, Pizarro C, Azevedo NF, Almeida C, Cerqueira L.   +8 more
europepmc   +1 more source

Peptide nucleic acid – zirconium coordination nanoparticles [PDF]

, 2022
Öztürk, Özgür
core  

Affinity Purification of DNA and RNA from Environmental Samples with Peptide Nucleic Acid Clamps

, 2000
Darrell P. Chandler, Jennie R. Stults, Sharon Cebula, Beatrice L. Schuck, Derek W. Weaver, Kevin K. Anderson, Michael D. Miller, Fred J. Brockman   +7 more
openalex   +1 more source

Application of peptide nucleic acid (PNA) for detection of transcription factors binding probes [PDF]

, 2002
Fumihiro Fujimori, Fumihiko Kitagawa, Yuko Abe, Y. Ohori, Ryohei Kiyota, Y. Nakamura, H Ikeda, Yasufumi Murakami   +7 more
openalex   +1 more source

Applications of Artificial Intelligence in Drug Repurposing

Advanced Science, Volume 12, Issue 14, April 10, 2025.
Artificial intelligence algorithms are transforming drug repurposing by revealing new therapeutic targets and mechanisms. This review highlights the integration of AI frameworks, multimodal datasets, and advanced optimization methods, accelerating the discovery of new indications for existing drugs.
Zhaoman Wan, Xinran Sun, Yi Li, Tianyao Chu, Xueyu Hao, Yang Cao, Peng Zhang   +6 more
wiley   +1 more source

Astrobiological implications of the stability and reactivity of peptide nucleic acid (PNA) in concentrated sulfuric acid. [PDF]

Sci Adv
Petkowski JJ, Seager S, Seager MD, Bains W, Marinus N, Poizat M, Plumet C, van Wiltenburg J, Visser T, Poelert M.   +9 more
europepmc   +1 more source

Characteristics and prognostic analysis of patients with detected KRAS mutations in resected lung adenocarcinomas by peptide nucleic acid-locked nucleic acid polymerase chain reaction (PNA-LNA PCR) clamp method. [PDF]

Transl Lung Cancer Res, 2023
Hashimoto T, Owada Y, Katagiri H, Yakuwa K, Tyo K, Sugai M, Fuzimura I, Utsumi Y, Akiyama M, Nagashima H, Terasaki H, Yanagawa N, Saito H, Sugai T, Maemondo M.   +14 more
europepmc   +1 more source

Affinity‐Based Isolation and One‐Pot Analysis of Extracellular Vesicles from Biofluids Using Phase Separated Zwitterionic Coacervates

Advanced Science, EarlyView.
This study presents a novel method for affinity‐based isolation and analysis of extracellular vesicles from biofluids using phase‐separated zwitterionic coacervates functionalized with a membrane‐sensing peptide. This technology minimizes nonspecific binding, enabling high‐yield isolation and direct one‐pot biomarker profiling.
Francesca Torrini, Roberto Frigerio, Jonathan Garlipp, Philippe Lenzen, Karl Normak, Carolina Paganini, Marina Cretich, Alessandro Gori, Paolo Arosio   +8 more
wiley   +1 more source

Revealing the Potential of a Chimaera: a Peptide-Peptide Nucleic Acid Molecule Designed To Interact with the SARS-CoV-2 Nucleocapsid Protein. [PDF]

Angew Chem Int Ed Engl
Tino AS, Quagliata M, Schiavina M, Pacini L, Papini AM, Felli IC, Pierattelli R.   +6 more
europepmc   +1 more source