Results 221 to 230 of about 344,433 (343)

LncDARS‐AS1 Regulates ATP1A1 Stability and Enhances Na+/K+ ATPase Activity to Promote Osteosarcoma Metastasis

Advanced Science, EarlyView.
This study identifies LncDARS‐AS1 as a novel oncogenic regulator that stabilizes ATP1A1 and enhances Na⁺/K⁺ ATPase activity, promoting osteosarcoma metastasis. Targeting the LncDARS‐AS1/ATP1A1/NKA axis, including pharmacological inhibition with digoxin, offers promising opportunities for the development of new therapeutic strategies against ...
Mingxian Xu, Jiatian Wei, Xiaoyu Feng, Qinkai Zhang, Jian Chen, Xinyue Wang, Xiudan Zhan, Bing Lu, Weitang Guo, Mingzhe Cheng, Renxuan Huang, Shao Xu, Changye Zou   +12 more
wiley   +1 more source

Peptide nucleic acid-immobilised paper combined with multiplex recombinase polymerase amplification for the ultrasensitive and rapid detection of rifampicin-resistant tuberculosis. [PDF]

Sci Rep
Jirakittiwut N, Sathianpitayakul P, Santanirand P, Akeda Y, Vilaivan T, Ratthawongjirakul P.   +5 more
europepmc   +1 more source

Nanomechanical assay for ultrasensitive and rapid detection of SARS-CoV-2 based on peptide nucleic acid. [PDF]

Nano Res, 2023
Wang Y, Yan T, Mei K, Rao D, Wu W, Chen Y, Peng Y, Wang J, Wu S, Zhang Q.   +9 more
europepmc   +1 more source

Hybridization and Melting Behavior of Peptide Nucleic Acid (PNA) Oligonucleotide Chimeras Conjugated to Gold Nanoparticles [PDF]

, 2004
D.M. Murphy, Gareth Redmond, Beatriz G. de la Torre, Ramón Eritja   +3 more
openalex   +1 more source

m6A‐Modified circRAPGEF1 Interaction with IGF2BP3 Promotes Hepatocellular Carcinoma Progression via Reprogramming Aspartate Metabolism

Advanced Science, EarlyView.
In hepatocellular carcinoma (HCC), the m6A‐modified circRAPGEF1 destabilizes ASS1 mRNA via competitive binding to IGF2BP3, driving aspartate metabolic reprogramming in liver cancer stem cells (LCSCs). This cascade enhances stemness properties and reduces sorafenib sensitivity in LCSCs, thereby identifying circRAPGEF1 as a promising therapeutic target ...
Juanyi Shi, Sintim Mui, Yongcong Yan, Shaomin Liu, Kai Wen, Chuanchao He, Huoming Li, Hao Liao, Meng Tao, Jiahua Wen, Weidong Wang, Xiaoding Xu, Zhenyu Zhou, Zhiyu Xiao   +13 more
wiley   +1 more source

Novel Small Multilamellar Liposomes Containing Large Quantities of Peptide Nucleic Acid Selectively Kill Breast Cancer Cells. [PDF]

Cancers (Basel), 2022
Proshkina G, Shramova E, Ryabova A, Katrivas L, Giannini C, Malpicci D, Levi-Kalisman Y, Deyev S, Kotlyar A.   +8 more
europepmc   +1 more source

Functional Dissection of RNA Polymerase III Termination Using a Peptide Nucleic Acid as a Transcriptional Roadblock [PDF]

, 2004
Elisa Guffanti, Roberto Corradini, Simone Ottonello, Giorgio Dieci   +3 more
openalex   +1 more source

The NSP5, ORF6 and NSP13 of SARS‐CoV‐2 Cooperate to Modulate Inflammatory Cell Death Activation

Advanced Science, EarlyView.
ZBP1 is capable of initiating a large cell death complex to induce programmed cell death during SARS‐CoV‐2 infection. However, SARS‐CoV‐2 can inhibit the activation of ZBP1‐mediated cell death by targeting key components of this complex. This suppression of ZBP1‐mediated cell death may account for the increased mortality observed in patients co ...
Huan Wang, Mengdi Liang, Jing Zhang, Hua Tong, Fenfen Zhang, Ying Liu, Pui Wang, Mengmeng Chang, Fei Han, Siwen Liu, Yongping Lin, Wenjun Song, Rajendra Karki, Peihui Wang, Honglin Chen, Yang Liu, Min Zheng   +16 more
wiley   +1 more source

Electrophoretically Snagging Viral Genomes in Wormlike Micelle Networks Using Peptide Nucleic Acid Amphiphiles and dsDNA Oligomers. [PDF]

Biomacromolecules
Hui K, Yan L, Schneider JW.
europepmc   +1 more source

The peptide nucleic acids: a new way for chromosomal investigation on isolated cells? [PDF]

, 2004
Franck Pellestor
openalex   +1 more source