Results 111 to 120 of about 2,973,844 (208)

Antisense properties of peptide nucleic acid

, 1999
Peptide nucleic acid (PNA) is a nucleic acid mimic in which the deoxyribose phosphate backbone has been replaced by a pseudo-peptide polymer to which the nucleobases are linked.
Larsen, H J, Nielsen, Peter Eigil, Bentin, T, Larsen, H. Jakob, Bentin, Thomas, Nielsen, Peter E.   +5 more
core   +1 more source

Modulating gene function with peptide nucleic acids (PNA)

, 2008
A review on peptide nucleic acid (PNA) oligomers as modulators of gene expression ranging from gene silencing at the mRNAor the dsDNA (antigene) level, and redirection of mRNA splicing to gene activation through transcription bubble mimicking. PNA chem.,
Crooke, Stanley T., Nielsen, Peter E.
core   +1 more source

Development of 2'-o-methyloligoribonucleotide and peptide nucleic acid based artificial ribonucleases

, 2007
We have developed 2'-O-methyloligoribonucleotide and peptide nucleic acid (PNA) based artificial ribonucleases (OBAN's), which in presence of zinc or copper ions cleave a potential therapy target in leukemia, an M-BCR/ABL mRNA model.
Strömberg, R,, Murtola, M,
core   +1 more source

Impact upon clinical outcomes of translation of PNA FISH-generated laboratory data from the clinical microbiology bench to bedside in real time

Therapeutics and Clinical Risk Management, 2008
Tam Ly, Jyoti Gulia, Vasilios Pyrgos, Masashi Waga, Shmuel ShohamSection of Infectious Diseases, Washington Hospital Center, Washington DC, USAAbstract: Fluorescence in situ hybridization using peptide nucleic acid probes (PNA-FISH) differentiates ...
Tam Ly, Jyoti Gulia, Vasilios Pyrgos, Masashi Waga, Shmuel Shoham   +4 more
doaj  

Preparation and SPECT/CT Imaging of ¹⁷⁷Lu-Labeled Peptide Nucleic Acid (PNA) Targeting CITED1: Therapeutic Evaluation in Tumor-Bearing Nude Mice. [PDF]

Onco Targets Ther, 2020
Li J, Zhang L, Li W, Lei C, Cao Y, Wang Y, Wang Z, Pang H.   +7 more
europepmc   +1 more source

Native Chemical Ligation Directed by Photocleavable Peptide Nucleic Acid (PNA) Templates

, 2017
A novel peptide-peptide ligation strategy is introduced that has the potential to provide peptide libraries of linearly or branched coupled fragments and will be suited to introduce simultaneous protein modifications at different ligation sites. Ligation
Cornelia H. Panse, Panse, Cornelia H., Swantje Nawratil, Nawratil, Swantje, Stephen Middel, Middel, Stephen, Ulf Diederichsen, Diederichsen, Ulf   +7 more
core   +1 more source

Peptide Nucleic Acid (PNA)-Enhanced Specificity of a Dual-Target Real-Time Quantitative Polymerase Chain Reaction (RT-qPCR) Assay for the Detection and Differentiation of SARS-CoV-2 from Related Viruses. [PDF]

Diagnostics (Basel), 2020
Choi WS, Jeong JH, Nicolas HDG, Oh S, Antigua KJC, Park JH, Kim B, Yoon SW, Shin KS, Choi YK, Baek YH, Song MS.   +11 more
europepmc   +1 more source

Parallel Synthesis of PNA-Peptide Conjugate Libraries

, 2002
peptide nucleic acid, PNA libraries, parallel PNA synthesis, PNA peptide ...
Awasthi, Satish Kumar, Nielsen, Peter Eigil   +1 more
core  

A Peptide Nucleic Acid (PNA) Masking the miR-145-5p Binding Site of the 3'UTR of the Cystic Fibrosis Transmembrane Conductance Regulator (CFTR) mRNA Enhances CFTR Expression in Calu-3 Cells. [PDF]

Molecules, 2020
Sultan S, Rozzi A, Gasparello J, Manicardi A, Corradini R, Papi C, Finotti A, Lampronti I, Reali E, Cabrini G, Gambari R, Borgatti M.   +11 more
europepmc   +1 more source

Peptide nucleic acid (PNA) clamps reduce amplification of host chloroplast and mitochondria rRNA gene sequences and increase detected diversity in 16S rRNA gene profiling analysis of oak-associated microbiota. [PDF]

Environ Microbiome
Hussain U, Downie J, Ellison A, Denman S, McDonald J, McDonald J, Cambon MC.   +6 more
europepmc   +2 more sources