Perspectives on conformationally constrained peptide nucleic acid (PNA): insights into the structural design, properties and applications. [PDF]
RSC Chem Biol, 2022 Suparpprom C, Vilaivan T.
europepmc +1 more source
Peptide nucleic acid (PNA) and its applications in chemical biology, diagnostics, and therapeutics
, 2019 Peptide nucleic acid (PNA) stands as one of the most successful artificial oligonucleotide mimetics. Salient features include the stability of hybridization complexes (either as duplexes or triplexes), metabolic stability, and ease of chemical ...
Winssinger, Nicolas +2 more
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Molecules, 2015 Peptide nucleic acids (PNAs) are structural mimics of nucleic acids that form stable hybrids with DNA and RNA. In addition, PNAs can invade double-stranded DNA.
Takuya Akisawa +2 more
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Effectiveness of blocking primers and a peptide nucleic acid (PNA) clamp for 18S metabarcoding dietary analysis of herbivorous fish. [PDF]
PLoS One, 2022 Homma C +6 more
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Treatment of Human Glioblastoma U251 Cells with Sulforaphane and a Peptide Nucleic Acid (PNA) Targeting miR-15b-5p: Synergistic Effects on Induction of Apoptosis. [PDF]
Molecules, 2022 Gasparello J +8 more
europepmc +1 more source
Strand Invasion of Mixed-Sequence B-DNA by Acridine-Linked, γ-Peptide Nucleic Acid (γ-PNA)
, 2016 Peptide nucleic acid (PNA) is a synthetic mimic of DNA and RNA that can recognize double-stranded B-DNA through direct Watson−Crick base-pairing. Although promising, PNA recognition is presently limited to mostly purine- and pyrimidine-rich targets ...
Bruce A. Armitage (1247022) +4 more
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Peptide nucleic acid (PNA) antisense effects in Escherichia coli
, 1999 Antisense peptide nucleic acid (PNA) can be used to control cell growth, gene expression and growth phenotypes in the bacteria Escherichia coli. PNAs targeted to the RNA components of the ribosome can inhibit translation and cell growth, and PNAs ...
Nielsen, P E, Good, L
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, 2015 Stopped-flow technique is useful for studying fast reactions that have half-lives as short as a few milliseconds.(a) This technique has never been used to study the interaction between Peptide nucleic acids (PNA) and DNA strands in the formation of ...
C. Carrara +5 more
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Structural Insights on Tiny Peptide Nucleic Acid (PNA) Analogues of miRNA-34a: An in silico and Experimental Integrated Approach. [PDF]
Front Chem, 2020 Moccia M +6 more
europepmc +1 more source
Site-selective DNA hydrolysis induced by a metal-free peptide nucleic acid-cyclen conjugate
, 2011 A metal-free artificial restriction DNA cutter which is composed of cyclen and classical peptide nucleic acid (PNA) was synthesized.
Zhang, Da-Wei +10 more
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