Antimicrobial peptide identification using multi-scale convolutional network [PDF]
Background: Antibiotic resistance has become an increasingly serious problem in the past decades. As an alternative choice, antimicrobial peptides (AMPs) have attracted lots of attention.
Quan, Xiongwen +4 more
core +1 more source
Citation: 'peptide nucleic acid' in the IUPAC Compendium of Chemical Terminology, 5th ed.; International Union of Pure and Applied Chemistry; 2025. Online version 5.0.0, 2025. 10.1351/goldbook.09714 • License: The IUPAC Gold Book is licensed under Creative Commons Attribution-ShareAlike CC BY-SA 4.0 International for individual terms.
openaire +1 more source
Antibiotic resistance evolved via inactivation of a ribosomal RNA methylating enzyme. [PDF]
Modifications of the bacterial ribosome regulate the function of the ribosome and modulate its susceptibility to antibiotics. By modifying a highly conserved adenosine A2503 in 23S rRNA, methylating enzyme Cfr confers resistance to a range of ribosome ...
Fujimori, Danica Galonić +3 more
core
Nucleic acid molecules are emerging as potential therapeutic tools, as evidenced by the transfection of small interfering RNA (siRNA) molecules in therapeutic applications and messenger RNAs in immunotherapeutic vaccination.
Clémentine Ayélé Teko-Agbo +7 more
doaj +1 more source
Recent Advancements in Development and Therapeutic Applications of Genome-Targeting Triplex-Forming Oligonucleotides and Peptide Nucleic Acids. [PDF]
Mikame Y, Yamayoshi A.
europepmc +1 more source
Variation of Tetrahydrofurans in Thyclotides Enhances Oligonucleotide Binding and Cellular Uptake of Peptide Nucleic Acids. [PDF]
Zheng H +5 more
europepmc +1 more source
Pyrenebutyrate Enhances the Antibacterial Effect of Peptide-Coupled Antisense Peptide Nucleic Acids in <i>Streptococcus pyogenes</i>. [PDF]
Abt C +5 more
europepmc +1 more source
Solid-phase synthesis of negatively charged oligomeric polyamide mimetics of nucleic acids
A Boc-protocol for manual solid-phase synthesis of novel sequences of negatively charged oligomeric polyamide mimetics of nucleic acids with a regular structure of the pseudopeptide backbone based on L-glutamic acid and glycine and having various ...
M. V. Shiryaeva +5 more
doaj
Unlocking the potential of chemically modified peptide nucleic acids for RNA-based therapeutics. [PDF]
Pradeep SP, Malik S, Slack FJ, Bahal R.
europepmc +1 more source

