Results 81 to 90 of about 611,085 (327)
Kelvin Probe Force Microscopy in Bionanotechnology: Current Advances and Future Perspectives
Advanced Materials, EarlyView.Kelvin probe force microscopy (KPFM) enables the nanoscale mapping of electrostatic surface potentials. While widely applied in materials science, its use in biological systems remains emerging. This review presents recent advances in KPFM applied to biological samples and provides a critical perspective on current limitations and future directions for
Ehsan Rahimi +4 more
wiley +1 more source
Peptide-Based Nanoassemblies in Gene Therapy and Diagnosis: Paving the Way for Clinical Application
Molecules, 2020 Nanotechnology approaches play an important role in developing novel and efficient carriers for biomedical applications. Peptides are particularly appealing to generate such nanocarriers because they can be rationally designed to serve as building blocks
Shabnam Tarvirdipour +4 more
doaj +1 more source
Synthetic Procedures for Peptide Nucleic Acids [PDF]
, 2004 A novel class of compounds, known as peptide nucleic acids, bind complementary ssDNA and RNA strands more strongly than a corresponding DNA. The peptide nucleic acids generally comprise ligands such as naturally occurring DNA bases attached to a peptide ...
Engholm, Michael +3 more
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Mesoporous Silica Nanoparticles in Biomedicine: Advances and Prospects
Advanced Materials, EarlyView.Mesoporous silica nanoparticles offer unique properties like high surface area, tunable pores, and functionalization. They excel in drug delivery, tissue engineering, and stimuli‐responsive therapies, enabling targeted and controlled treatments. With roles in cancer therapy and diagnostics, their clinical translation requires addressing challenges in ...
Miguel Manzano, María Vallet‐Regí
wiley +1 more source
Polyanionic Carboxyethyl Peptide Nucleic Acids (ce-PNAs): Synthesis and DNA Binding.
PLoS ONE, 2015 New polyanionic modifications of polyamide nucleic acid mimics were obtained. Thymine decamers were synthesized from respective chiral α- and γ-monomers, and their enantiomeric purity was assessed. Here, we present the decamer synthesis, purification and
Yuliya Kirillova +9 more
doaj +1 more source
Formulation of a Peptide Nucleic Acid Based Nucleic Acid Delivery Construct [PDF]
Bioconjugate Chemistry, 2010 Gene delivery biomaterials need to be designed to efficiently achieve nuclear delivery of plasmid DNA. Polycations have been used to package DNA and other nucleic acids within submicrometer-sized particles, offering protection from shear-induced or enzymatic degradation.
Peter G, Millili +4 more
openaire +2 more sources
Tailoring Peptide Nucleic Acids for Enhanced RNA-Targeting [PDF]
, 2023 Peptide nucleic acids (PNAs) represent nucleic acid mimics featuring a peptide backbone composed of N-(2-aminoethyl)glycine units, deviating from the conventional sugar-phosphate core.
Lenz, Agnes +3 more
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Recent Advances in Ferrite‐Based Materials for Biomedical Applications: A Comprehensive Review
Advanced Materials, EarlyView.Ferrite nanoplatforms are presented as tunable biomedical materials in which synthesis control, cation engineering, defect/morphology regulation, and surface functionalization govern structure–property–bioactivity relationships. These design strategies enable multifunctional applications including MRI contrast, magnetic hyperthermia, targeted drug ...
Pramod D. Mhase +6 more
wiley +1 more source
Peptide Nucleic Acid-Based Biosensors for Cancer Diagnosis
Molecules, 2017 The monitoring of DNA and RNA biomarkers freely circulating in the blood constitutes the basis of innovative cancer detection methods based on liquid biopsy.
Roberta D’Agata +2 more
doaj +1 more source
Histidine-Containing Peptide Nucleic Acids [PDF]
, 2000 Peptide nucleic acids containing histidine moieties are provided.
Engholm, Michael +3 more
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