Isolation of active genes containing CAG repeats by DNA strand invasion by a peptide nucleic acid. [PDF]
L.C. Boffa+2 more
openalex +1 more source
Progress in genome research led to new perspectives in diagnostic applications and to new promising therapies. On account of their specificity and sensitivity, nucleic acids (DNA/RNA) increasingly are in the focus of the scientific interest.
Manfred Wiessler, Waldemar Waldeck, Ruediger Pipkorn, Christian Kliem, Peter Lorenz, Heinz Fleischhacker, Manuel Hafner, Klaus Braun
doaj
Information transfer from peptide nucleic acids to RNA by template- directed syntheses [PDF]
Jürgen Schmidt
openalex +1 more source
Peptide nucleic acid (PNA): its medical and biotechnical applications and promise for the future [PDF]
Arghya Ray, Bengt Nordén
openalex +1 more source
Peptide nucleic acids: versatile tools for gene therapy strategies [PDF]
David A. Dean
openalex +1 more source
Inhibition of telomerase activity by a cell‐penetrating peptide nucleic acid construct in human melanoma cells [PDF]
Raffaella Villa+5 more
openalex +1 more source
Enhanced Sampling Algorithms [PDF]
In biomolecular systems (especially all-atom models) with many degrees of freedom such as proteins and nucleic acids, there exist an astronomically large number of local-minimum-energy states. Conventional simulations in the canonical ensemble are of little use, because they tend to get trapped in states of these energy local minima.
arxiv
Applications of Enhanced Sampling Methods to Biomolecular Self-Assembly: A Review [PDF]
This review article discusses some common enhanced sampling methods in relation to the process of self-assembly of biomolecules. An introduction to self-assembly and its challenges is covered followed by a brief overview of the methods and analysis for replica-exchange molecular dynamics, umbrella sampling, metadynamics, and machine learning based ...
arxiv
Peptide Nucleic Acids: Methods and Protocols
P. Nielsen
semanticscholar +1 more source
Pyrenebutyrate Enhances the Antibacterial Effect of Peptide-Coupled Antisense Peptide Nucleic Acids in Streptococcus pyogenes. [PDF]
Abt C+5 more
europepmc +1 more source