Progressive Insights into 3D Bioprinting for Corneal Tissue Restoration
Advanced Healthcare Materials, EarlyView.This review explores the potential of 3D bioprinting to replicate the complex structure and function of the human cornea. It highlights key advances in bioink development, printing modalities, and in vivo performance, while addressing current challenges and emerging strategies. The review emphasizes bioprinting's promise to overcome donor shortages and
Ilayda Namli +6 more
wiley +1 more source
Peptide nucleic acid (PNA): its medical and biotechnical applications and promise for the future [PDF]
, 2000 Arghya Ray, Bengt Nordén
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Identification of the prebiotic translation apparatus within the contemporary ribosome [PDF]
, 2009 A structural element that could have existed independently in the prebiotic era was identified at the active site of the contemporary ribosome. It is suggested to have functioned as a proto-ribosome catalyzing peptide bond formation and non-coded ...
Ada Yonath +3 more
core +1 more source
Advanced Healthcare Materials, EarlyView.Polymer‐based drug delivery systems can effectively overcome the limitations of free drugs in terms of solubility, stability, and plasma half‐life, yet their development has traditionally relied on time‐consuming trial‐and‐error approaches. This review highlights recent advances in applying molecular simulation to the design of polymer‐based drug ...
Ping Gao +4 more
wiley +1 more source
Peptide nucleic acids: versatile tools for gene therapy strategies [PDF]
, 2000 David A. Dean
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Antimicrobial peptide identification using multi-scale convolutional network [PDF]
, 2019 Background: Antibiotic resistance has become an increasingly serious problem in the past decades. As an alternative choice, antimicrobial peptides (AMPs) have attracted lots of attention.
Quan, Xiongwen +4 more
core +1 more source
Strategies to Improve the Lipophilicity of Hydrophilic Macromolecular Drugs
Advanced Healthcare Materials, EarlyView.Hydrophilic macromolecular drugs can be successfully lipidized by covalent attachment of lipids, by hydrophobic ion pairing with negatively or positively charged surfactants, and by dry or wet reverse micelle formation. Lipophilicity enhancement of hydrophilic macromolecules has several benefits including stability and bioavailability improvement ...
Sera Lindner +8 more
wiley +1 more source
Inhibition of telomerase activity by a cell‐penetrating peptide nucleic acid construct in human melanoma cells [PDF]
, 2000 Raffaella Villa +5 more
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DNA‑Directed Assembly of Photonic Nanomaterials for Diagnostic and Therapeutic Applications
Advanced Materials, EarlyView.DNA‐directed assembly offers a powerful strategy for constructing structured photonic nanomaterials with precise spatial control. This review provides a comprehensive overview of recent advancements in DNA‐assembled photonic nanomaterials for diagnostics and therapeutics, highlighting key design principles, functionalization strategies, and optical ...
Longjiang Ding +5 more
wiley +1 more source
Light‐Harvesting Nanomaterials Based on Dyes for Energy Transfer and Amplified Biosensing
Advanced Materials, EarlyView.Light harvesting (LH) in plants inspires researchers to develop artificial LH nanomaterials. Here, LH nanomaterials based on organic dyes are reviewed, considering fundamental challenges on aggregation‐caused quenching, excitation energy transfer, and exciton migration length.
Andrey S. Klymchenko +2 more
wiley +1 more source