Treatment options for PNET liver metastases. a systematic review [PDF]
Pancreatic neuroendocrine tumors (PNETs) are rare pancreatic neoplasms. About 40-80% of patients with PNET are metastatic at presentation, usually involving the liver (40-93%). Liver metastasis represents the most significant prognostic factor.
Aurello, Paolo +8 more
core +1 more source
Relationships between uptake of [68Ga]Ga-DOTA-TATE and absorbed dose in [177Lu]Lu-DOTA-TATE therapy
Background Somatostatin receptor 68Ga PET imaging is standard for evaluation of a patient’s suitability for 177Lu peptide receptor radionuclide therapy of neuroendocrine tumours (NETs).
Anna Stenvall +8 more
doaj +1 more source
Background Mainly severe (CTCAE grade 3–4) haematotoxicity during peptide receptor radionuclide therapy (PRRT) is reported in literature due to major clinical impact, however moderate (CTCAE grade 2) haematotoxicity is common and could affect therapy ...
Daphne M. V. de Vries–Huizing +8 more
doaj +2 more sources
Radiolabeled CCK/gastrin peptides for imaging and therapy of CCK2 receptor-expressing tumors [PDF]
Cholecystokinin (CCK) receptors are overexpressed in numerous human cancers, like medullary thyroid carcinomas, small cell lung cancers and stromal ovarian cancers.
Susan Roosenburg +46 more
core +1 more source
177Lu-DOTATATE Peptide Receptor Radionuclide Therapy [PDF]
The peptide receptor radionuclide therapy (PRRT) 177Lu-DOTATATE binds to somatostatin receptors ([1][1]). A multidisciplinary team should be involved when treating patients with 177Lu-DOTATATE PRRT, including medical oncologists, nuclear medicine physicians and technologists, nurses ...
Amanda, Abbott, Heather, Jacene
openaire +3 more sources
A 35-year-old man presented with significant weight loss of 30 kg over the previous 6 months, with newly diagnosed diabetes. Routine laboratory tests were normal, except for markedly elevated blood glucose.
Ahmed Fathala, MD +2 more
doaj +1 more source
Simplified dosimetry for kidneys and tumors in 177Lu-labeled peptide receptor radionuclide therapy
Purpose To evaluate if satisfactory post-therapeutic image-based dosimetry can be achieved for Lu-177-DOTATATE treatments using a reduced number of image acquisitions to improve patient comfort and reduce economical costs.
Oscar Ardenfors +3 more
doaj +1 more source
The Integration of Positron Emission Tomography With Magnetic Resonance Imaging [PDF]
A number of laboratories and companies are currently exploring the development of integrated imaging systems for magnetic resonance imaging (MRI) and positron emission tomography (PET).
Cherry, Simon R. +2 more
core +1 more source
Efficacy of Peptide Receptor Radionuclide Therapy for Esthesioneuroblastoma [PDF]
Esthesioneuroblastoma is rare, with limited therapeutic options when unresectable or metastatic; however, expression of somatostatin receptors qualifies it for peptide receptor radionuclide therapy (PRRT). We report outcomes of PRRT in esthesioneuroblastoma from 2 referral centers.
Olfat Kamel, Hasan +6 more
openaire +2 more sources
[111In-DTPA]octreotide tumor uptake in GEPNET liver metastases after intra-arterial administration: An overview of preclinical and clinical observations and implications for tumor radiation dose after peptide radionuclide therapy [PDF]
Aims: With the aim to improve peptide receptor radionuclide therapy effects in patients with gastroenteropancreatic neuroendocrine tumor (GEPNET) liver metastases we explored the effect of intra-arterial (IA) administration of [111In-DTPA]octreotide ...
Breeman, W.A.P. (Woulter) +8 more
core +2 more sources

