Results 231 to 240 of about 483,403 (312)

Leveraging Organ‐on‐Chip Models to Investigate Host–Microbiota Dynamics and Targeted Therapies for Inflammatory Bowel Disease

open access: yesAdvanced Healthcare Materials, EarlyView.
The challenges of studying inflammatory bowel disease (IBD), highlighting limitations of traditional 2D cell cultures and animal models are discussed here. It introduces human intestine organ‐on‐chip (OoC) models as a promising alternative, capable of more accurately mimicking the intestinal microenvironment.
Tim Kaden   +5 more
wiley   +1 more source

Urine‐Stable Aptamer‐Conjugated Gold Nanorods for the Early Detection of High‐Grade Bladder Cancer Residual Disease

open access: yesAdvanced Healthcare Materials, EarlyView.
Aptamer (A) conjugated gold nanorods (B) for the recognition of bladder cancer cells expressing the integrin α5β1 (C) and the visualization of the targeted GNRs@Chit‐Apt‐Itg by photoacoustic imaging at the surface of the orthotopic bladder cancer in the preclinical model (D).
Chiara Venegoni   +15 more
wiley   +1 more source

In Situ‐Gelling Antimicrobial Poly(oligoethylene glycol methacrylate)‐Based Hydrogels Integrating Bound Quaternary Ammonia Compounds and Antibiotic Functionalities for Effective Infected Wound Healing

open access: yesAdvanced Healthcare Materials, EarlyView.
In situ‐gelling poly(oligoethylene glycol methacrylate) (POEGMA)‐based hydrogels exhibit broad‐spectrum antibacterial activity against both gram‐positive and gram‐negative bacteria based on the dual covalent attachment of quaternary ammonium (QA) groups and the antibiotic ciprofloxacin (CIP) into the hydrogel networks, enabling effective in vivo burn ...
Fei Xu   +8 more
wiley   +1 more source

Viscoelastic HyA Hydrogel Promotes Recovery of Muscle Quality and Vascularization in a Murine Model of Delayed Rotator Cuff Repair

open access: yesAdvanced Healthcare Materials, EarlyView.
Rotator cuff tears, a common musculotendinous injury, often lead to permanent functional disability. A novel hyaluronic acid‐based hydrogel shows promise in promoting muscle regeneration after rotator cuff repair. The hydrogel reduces fibrosis, fatty infiltration, and muscle atrophy while supporting vascularization in a murine model.
Morgan R. Pfaff   +11 more
wiley   +1 more source

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