Results 121 to 130 of about 186,549 (302)

Characterization of human cytomegalovirus peptide-specific CD8⁺ T-cell repertoire diversity following in vitro restimulation by antigen-pulsed dendritic cells

, 2002
Under conditions of impaired T-cell immunity, human cytomegalovirus (HCMV) can reactivate from lifelong latency, resulting in potentially fatal disease.
Moss, Paul; id_orcid, Karl Peggs, Moss, P, Pizzey, A, Stephanie Verfuerth, Ainsworth, Jennifer, Peggs, K, Verfuerth, S, Mackinnon, S, Ainsworth, J, Paul Moss, Stephen Mackinnon, Jenni Ainsworth, Arnold Pizzey   +13 more
core   +1 more source

Data_Sheet_13_A toxin-based approach to neuropeptide and peptide hormone discovery.DOCX

, 2023
Peptide hormones and neuropeptides form a diverse class of bioactive secreted molecules that control essential processes in animals. Despite breakthroughs in peptide discovery, many signaling peptides remain undiscovered.
Thomas Lund Koch (16748835), Helena Safavi-Hemami (365225), Joshua P. Torres (10750989), Kevin Chase (10449802), Paula Flórez Salcedo (16748829), Baldomero M. Olivera (369455), Robert P. Baskin (16910715)   +6 more
core   +1 more source

One‐Step Microfluidic Manufactured Fucose‐Decorated Sweetosomes Choose the Time and the Road for Their Intracellular Journey to Cancer Treatment

Advanced Healthcare Materials, EarlyView.
Sweetosomes, a new class of fucose‐decorated liposomes, are developed via a one‐step microfluidic process without surface chemistry. This study elucidates their main caveolae‐mediated entry and distinct endosomal trafficking. These nanostructures demonstrate superior endosomal escape, organelle acidity modulation, and prolonged plasma persistence ...
Mattia Tiboni, Mariele Montanari, Shiva Khorshid, Michele Verboni, Andrea Duranti, Simone Lucarini, Daniele Lopez, Annalisa Aluigi, Gianluca Morganti, Michele Menotta, Giovanna Panza, Daniel J. Klionsky, Barbara Canonico, Luca Casettari   +13 more
wiley   +1 more source

Peptide-Guided System with Programmable Subcellular Translocation for Targeted Therapy and Bypassing Multidrug Resistance

, 2018
Nonselectivity and drug resistance are two major obstacles for cancer treatment. Although great advances have been made toward cell targeting or discovering novel delivery pathways, it is still desirable to simultaneously overcome the two hurdles for ...
Yuanyuan Zhu (418127), Yanyan Huang, Shilang Gui, Rui Zhao, Yuanyuan Zhu, Yulong Jin, Shilang Gui (1679674), Yulong Jin (1679677), Rui Zhao (43391), Yanyan Huang (199515)   +9 more
core   +1 more source

Epidermal Patch Technologies for Integrated Healthcare and Infection Management

Advanced Healthcare Materials, EarlyView.
Epidermal patches have evolved from simple wound coverings into multifunctional, skin‐conformable platforms integrating drug delivery, biosensing, and therapeutic functionalities. This review highlights their material innovations, fabrication strategies, and intelligent designs, including hydrogels, microneedles, and flexible electronics, while ...
Yuqi Wang, Atakan Tevlek, Pawel L. Urban, Boaz Mizrahi, Onome Ejeromedoghene, Roshan Deen, Yuanjing Lin, Jagan Mohan Dodda   +7 more
wiley   +1 more source

Characterization of the ToxB Gene from Pyrenophora tritici-repentis

Molecular Plant-Microbe Interactions, 2001
The ToxB gene was cloned and characterized from a race 5 isolate of Pyrenophora tritici-repentis from North Dakota. ToxB contains a 261-bp open reading frame that encodes a 23 amino acid putative signal peptide and a 64 amino acid host-selective toxin ...
J. Patrick Martinez, Sean A. Ottum, Shaukat Ali, Leonard J. Francl, Lynda M. Ciuffetti   +4 more
doaj   +1 more source

Immunoinflammatory Mechanisms and Biocompatibility of Bioactive Dental Biomaterials: From Fundamental Insights to Clinical Translation

Advanced Healthcare Materials, EarlyView.
Surface‐host dialogue at the implant interface governs biological fate and osseointegration. Surface physicochemical properties of titanium (Ti) dental implants, including microgrooves, nanopatterns, nanotopography, roughness, and wettability, modulate the initial adsorption of proteins and the formation of a dynamic biointerface.
Daniela Moreira Cunha, Amanda Paino Santana, Marta Maria Alves Pereira, Mariana Martins Guerreiro, Jose Mauro Granjeiro, Jamil Awad Shibli, Jeroen J. J. P. van den Beucken, Anton Sculean, Rafael Scaf de Molon, Erica Dorigatti de Avila   +9 more
wiley   +1 more source

Investigation of Peptide Toxin Diversity in Ribbon Worms (Nemertea) Using a Transcriptomic Approach. [PDF]

Toxins (Basel), 2022
Vlasenko AE, Kuznetsov VG, Magarlamov TY.   +2 more
europepmc   +1 more source

Natural Biomaterials for Osteochondral Repair: From Source to Strategy

Advanced Healthcare Materials, EarlyView.
Biological origin‐guided overview of natural biomaterials and therapeutic strategies for osteochondral tissue engineering. The circular diagram categorizes representative materials and strategies into plant/algae‐derived, microbial‐derived, animal‐derived, and human‐derived sources, centered on an osteochondral defect repair model.
Hengyu Liu, Hanyang Zhang, Wenbo Yang, Hao Chen, Jincheng Wang, Fei Chang   +5 more
wiley   +1 more source

Bacteria‐Responsive Nanostructured Drug Delivery Systems for Targeted Antimicrobial Therapy

Advanced Materials, EarlyView.
Bacteria‐responsive nanocarriers are designed to release antimicrobials only in the presence of infection‐specific cues. This selective activation ensures drug release precisely at the site of infection, avoiding premature or indiscriminate release, and enhancing efficacy.
Guillermo Landa, Gracia Mendoza, Silvia Irusta, Manuel Arruebo   +3 more
wiley   +1 more source