Moving in for the Kill: Activation of an Endoribonuclease Toxin by a Quorum-Sensing Peptide
, 2011 Extracellular death factor is a quorum-sensing pentapeptide that relays cell density information to an intracellular toxin-antitoxin complex. In this issue of Molecular Cell, Belitsky et al. (2011) demonstrate that the peptide competes with the antitoxin
Hayes, Finbarr, Finbarr Hayes
core +1 more source
Kelvin Probe Force Microscopy in Bionanotechnology: Current Advances and Future Perspectives
Advanced Materials, EarlyView.Kelvin probe force microscopy (KPFM) enables the nanoscale mapping of electrostatic surface potentials. While widely applied in materials science, its use in biological systems remains emerging. This review presents recent advances in KPFM applied to biological samples and provides a critical perspective on current limitations and future directions for
Ehsan Rahimi +4 more
wiley +1 more source
Receptor-kinase EGFR-MAPK adaptor proteins mediate the epithelial response to Candida albicans via the cytolytic peptide toxin, candidalysin. [PDF]
J Biol Chem, 2022 Ponde NO +9 more
europepmc +1 more source
Mesoporous Silica Nanoparticles in Biomedicine: Advances and Prospects
Advanced Materials, EarlyView.Mesoporous silica nanoparticles offer unique properties like high surface area, tunable pores, and functionalization. They excel in drug delivery, tissue engineering, and stimuli‐responsive therapies, enabling targeted and controlled treatments. With roles in cancer therapy and diagnostics, their clinical translation requires addressing challenges in ...
Miguel Manzano, María Vallet‐Regí
wiley +1 more source
Eutectozymes as Soft Hybrid Materials for Advanced Biocatalysis
Advanced Materials, EarlyView.Eutectozymes are sustainable hybrid materials that embed a GOx–HRP cascade within hydrophobic eutectogels featuring a dual supramolecular–covalent network. This architecture preserves native enzyme structure and stability, enables efficient heterogeneous biocatalysis in aqueous media, and positions eutectogels as robust platforms for next‐generation ...
Manuel Eduardo Martinez Cartagena +10 more
wiley +1 more source
A peptide toxin in ant venom mimics vertebrate EGF-like hormones to cause long-lasting hypersensitivity in mammals. [PDF]
Proc Natl Acad Sci U S A, 2022 Eagles DA +13 more
europepmc +1 more source
Advanced Materials, EarlyView.Harnessing the synergistic interplay of supramolecular self‐assembly, under macromolecular crowding conditions, and enzymatic‐mediated covalent crosslinking toward a stable protein‐based G‐quadruplex‐derived supramolecular bioink. This bioinspired strategy enables the biofabrication of complex and tunable ECM‐mimetic constructs, providing a platform ...
Vera Sousa +6 more
wiley +1 more source
Mastoparan, a Peptide Toxin from Wasp Venom Conjugated Fluvastatin Nanocomplex for Suppression of Lung Cancer Cell Growth. [PDF]
Polymers (Basel), 2021 Alhakamy NA, Ahmed OAA, Md S, Fahmy UA.
europepmc +1 more source
Expanding the structural atlas of peptide toxins [PDF]
, 2019 Disulfide-rich peptides are wide spread in nature and as hormones and toxins play key biological roles for many organisms. Some families of disulfide-rich peptides are so large and diverse that they can be considered natural combinatorial libraries for drug discovery.
openaire +3 more sources
Advanced Materials, EarlyView.Controlling the protein corona formation onto carbon nanomaterials (CNMs) enhances their functionalities as platforms for cancer theranostics. Here, we reviewed the effects of the intrinsic and acquired properties of CNMs on protein corona formation, the consequent biological and toxicological outcomes, and the strategies to reshape corona formation ...
Yajuan Zou +5 more
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